| Full name: lipocalin 8 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 9q34.3 | ||
| Entrez ID: 138307 | HGNC ID: HGNC:27038 | Ensembl Gene: ENSG00000204001 | OMIM ID: 612902 |
| Drug and gene relationship at DGIdb | |||
Expression of LCN8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LCN8 | 138307 | 239369_at | -0.2746 | 0.2966 | |
| GSE26886 | LCN8 | 138307 | 239369_at | -0.2600 | 0.0477 | |
| GSE45670 | LCN8 | 138307 | 239369_at | -0.2792 | 0.0336 | |
| GSE53622 | LCN8 | 138307 | 30034 | 0.4437 | 0.0000 | |
| GSE53624 | LCN8 | 138307 | 30034 | 0.7518 | 0.0000 | |
| GSE63941 | LCN8 | 138307 | 1569614_s_at | -0.1145 | 0.4799 | |
| GSE77861 | LCN8 | 138307 | 239369_at | -0.2976 | 0.0213 | |
| GSE97050 | LCN8 | 138307 | A_33_P3272849 | -0.2130 | 0.3485 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LCN8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LCN8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LCN8 | 138307 | 5 | 7 | 18 | |
| GSE20123 | LCN8 | 138307 | 5 | 7 | 18 | |
| GSE43470 | LCN8 | 138307 | 3 | 7 | 33 | |
| GSE46452 | LCN8 | 138307 | 6 | 13 | 40 | |
| GSE47630 | LCN8 | 138307 | 6 | 15 | 19 | |
| GSE54993 | LCN8 | 138307 | 3 | 3 | 64 | |
| GSE54994 | LCN8 | 138307 | 12 | 8 | 33 | |
| GSE60625 | LCN8 | 138307 | 0 | 0 | 11 | |
| GSE74703 | LCN8 | 138307 | 3 | 5 | 28 | |
| GSE74704 | LCN8 | 138307 | 3 | 5 | 12 | |
| TCGA | LCN8 | 138307 | 29 | 23 | 44 |
Total number of gains: 75; Total number of losses: 93; Total Number of normals: 320.
Somatic mutations of LCN8:
Generating mutation plots.
Highly correlated genes for LCN8:
Showing top 20/297 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LCN8 | C1orf61 | 0.805204 | 3 | 0 | 3 |
| LCN8 | CNTFR | 0.775722 | 3 | 0 | 3 |
| LCN8 | GALR3 | 0.771601 | 4 | 0 | 4 |
| LCN8 | KCNJ13 | 0.766615 | 4 | 0 | 3 |
| LCN8 | CTSE | 0.766146 | 3 | 0 | 3 |
| LCN8 | PSPN | 0.750802 | 3 | 0 | 3 |
| LCN8 | NOBOX | 0.737417 | 3 | 0 | 3 |
| LCN8 | ANKRD33 | 0.737225 | 4 | 0 | 3 |
| LCN8 | IQCF3 | 0.733268 | 3 | 0 | 3 |
| LCN8 | FTHL17 | 0.732497 | 3 | 0 | 3 |
| LCN8 | KLK3 | 0.731131 | 3 | 0 | 3 |
| LCN8 | F2 | 0.730545 | 3 | 0 | 3 |
| LCN8 | VGLL2 | 0.725915 | 3 | 0 | 3 |
| LCN8 | SP6 | 0.722962 | 3 | 0 | 3 |
| LCN8 | MYL4 | 0.72203 | 4 | 0 | 4 |
| LCN8 | BEST4 | 0.721184 | 3 | 0 | 3 |
| LCN8 | OPRD1 | 0.719888 | 3 | 0 | 3 |
| LCN8 | GFRA2 | 0.715841 | 4 | 0 | 3 |
| LCN8 | FRMD1 | 0.715109 | 3 | 0 | 3 |
| LCN8 | CNPY1 | 0.712571 | 3 | 0 | 3 |
For details and further investigation, click here
