| Full name: zinc finger protein 253 | Alias Symbol: BMZF-1|FLJ90391 | ||
| Type: protein-coding gene | Cytoband: 19p13.11 | ||
| Entrez ID: 56242 | HGNC ID: HGNC:13497 | Ensembl Gene: ENSG00000256771 | OMIM ID: 606954 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF253:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF253 | 56242 | 206900_x_at | -0.2716 | 0.6438 | |
| GSE20347 | ZNF253 | 56242 | 206900_x_at | -0.1257 | 0.1270 | |
| GSE23400 | ZNF253 | 56242 | 206900_x_at | -0.0153 | 0.7532 | |
| GSE26886 | ZNF253 | 56242 | 206900_x_at | -0.1618 | 0.2000 | |
| GSE29001 | ZNF253 | 56242 | 206900_x_at | -0.2749 | 0.1778 | |
| GSE38129 | ZNF253 | 56242 | 206900_x_at | -0.1665 | 0.1950 | |
| GSE45670 | ZNF253 | 56242 | 206900_x_at | -0.1646 | 0.3359 | |
| GSE53622 | ZNF253 | 56242 | 69281 | -0.0899 | 0.4923 | |
| GSE53624 | ZNF253 | 56242 | 19858 | -0.6808 | 0.0000 | |
| GSE63941 | ZNF253 | 56242 | 206900_x_at | 0.2718 | 0.6446 | |
| GSE77861 | ZNF253 | 56242 | 206900_x_at | -0.3151 | 0.0493 | |
| GSE97050 | ZNF253 | A_21_P0000650 | -0.0855 | 0.8429 | ||
| SRP007169 | ZNF253 | 56242 | RNAseq | -0.4145 | 0.4630 | |
| SRP008496 | ZNF253 | 56242 | RNAseq | -0.2771 | 0.4214 | |
| SRP064894 | ZNF253 | 56242 | RNAseq | -0.4035 | 0.1382 | |
| SRP133303 | ZNF253 | 56242 | RNAseq | -0.1774 | 0.3900 | |
| SRP159526 | ZNF253 | 56242 | RNAseq | -0.2082 | 0.6290 | |
| SRP193095 | ZNF253 | 56242 | RNAseq | -0.3502 | 0.0980 | |
| SRP219564 | ZNF253 | 56242 | RNAseq | -0.2575 | 0.7017 | |
| TCGA | ZNF253 | 56242 | RNAseq | -0.4957 | 0.0125 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNF253 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF253:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF253 | 56242 | 3 | 5 | 22 | |
| GSE20123 | ZNF253 | 56242 | 3 | 3 | 24 | |
| GSE43470 | ZNF253 | 56242 | 2 | 6 | 35 | |
| GSE46452 | ZNF253 | 56242 | 47 | 1 | 11 | |
| GSE47630 | ZNF253 | 56242 | 5 | 8 | 27 | |
| GSE54993 | ZNF253 | 56242 | 17 | 3 | 50 | |
| GSE54994 | ZNF253 | 56242 | 6 | 13 | 34 | |
| GSE60625 | ZNF253 | 56242 | 9 | 0 | 2 | |
| GSE74703 | ZNF253 | 56242 | 2 | 4 | 30 | |
| GSE74704 | ZNF253 | 56242 | 0 | 3 | 17 | |
| TCGA | ZNF253 | 56242 | 16 | 12 | 68 |
Total number of gains: 110; Total number of losses: 58; Total Number of normals: 320.
Somatic mutations of ZNF253:
Generating mutation plots.
Highly correlated genes for ZNF253:
Showing top 20/204 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF253 | NIPSNAP3A | 0.742157 | 3 | 0 | 3 |
| ZNF253 | APPL1 | 0.731135 | 3 | 0 | 3 |
| ZNF253 | TOP2B | 0.715127 | 4 | 0 | 4 |
| ZNF253 | ZNF93 | 0.705622 | 10 | 0 | 9 |
| ZNF253 | ZNF738 | 0.68626 | 6 | 0 | 5 |
| ZNF253 | ZNF85 | 0.680393 | 11 | 0 | 9 |
| ZNF253 | ZNF43 | 0.672046 | 8 | 0 | 6 |
| ZNF253 | ZNF479 | 0.668129 | 3 | 0 | 3 |
| ZNF253 | ZNF709 | 0.658457 | 3 | 0 | 3 |
| ZNF253 | ZDHHC20 | 0.650064 | 4 | 0 | 4 |
| ZNF253 | WNK1 | 0.649459 | 3 | 0 | 3 |
| ZNF253 | PDIK1L | 0.645989 | 3 | 0 | 3 |
| ZNF253 | ZNF708 | 0.634259 | 4 | 0 | 3 |
| ZNF253 | CUL4B | 0.62927 | 4 | 0 | 3 |
| ZNF253 | ZNF844 | 0.627369 | 5 | 0 | 5 |
| ZNF253 | STT3B | 0.625607 | 4 | 0 | 3 |
| ZNF253 | ZNF823 | 0.625449 | 5 | 0 | 5 |
| ZNF253 | ZNF682 | 0.623146 | 8 | 0 | 6 |
| ZNF253 | BTN1A1 | 0.61852 | 3 | 0 | 3 |
| ZNF253 | ZNF254 | 0.617916 | 10 | 0 | 8 |
For details and further investigation, click here
