| Full name: methyltransferase like 25 | Alias Symbol: FLJ22789 | ||
| Type: protein-coding gene | Cytoband: 12q21.31 | ||
| Entrez ID: 84190 | HGNC ID: HGNC:26228 | Ensembl Gene: ENSG00000127720 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of METTL25:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | METTL25 | 84190 | 229018_at | -0.6050 | 0.1807 | |
| GSE26886 | METTL25 | 84190 | 229018_at | -0.4561 | 0.1594 | |
| GSE45670 | METTL25 | 84190 | 229018_at | -0.3474 | 0.0473 | |
| GSE53622 | METTL25 | 84190 | 63907 | -0.5341 | 0.0000 | |
| GSE53624 | METTL25 | 84190 | 63907 | -0.7124 | 0.0000 | |
| GSE63941 | METTL25 | 84190 | 229018_at | -0.9601 | 0.1359 | |
| GSE77861 | METTL25 | 84190 | 229018_at | -0.3380 | 0.0292 | |
| SRP007169 | METTL25 | 84190 | RNAseq | -1.1320 | 0.0134 | |
| SRP008496 | METTL25 | 84190 | RNAseq | -1.2535 | 0.0001 | |
| SRP064894 | METTL25 | 84190 | RNAseq | -0.4068 | 0.0146 | |
| SRP133303 | METTL25 | 84190 | RNAseq | -0.5104 | 0.0050 | |
| SRP159526 | METTL25 | 84190 | RNAseq | -0.7612 | 0.0212 | |
| SRP193095 | METTL25 | 84190 | RNAseq | -0.9717 | 0.0000 | |
| SRP219564 | METTL25 | 84190 | RNAseq | -0.1009 | 0.7742 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by METTL25 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of METTL25:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | METTL25 | 84190 | 2 | 4 | 24 | |
| GSE20123 | METTL25 | 84190 | 2 | 4 | 24 | |
| GSE43470 | METTL25 | 84190 | 3 | 1 | 39 | |
| GSE46452 | METTL25 | 84190 | 9 | 1 | 49 | |
| GSE47630 | METTL25 | 84190 | 10 | 1 | 29 | |
| GSE54993 | METTL25 | 84190 | 0 | 5 | 65 | |
| GSE54994 | METTL25 | 84190 | 7 | 1 | 45 | |
| GSE60625 | METTL25 | 84190 | 0 | 0 | 11 | |
| GSE74703 | METTL25 | 84190 | 3 | 1 | 32 | |
| GSE74704 | METTL25 | 84190 | 1 | 3 | 16 | |
| TCGA | METTL25 | 84190 | 19 | 10 | 67 |
Total number of gains: 56; Total number of losses: 31; Total Number of normals: 401.
Somatic mutations of METTL25:
Generating mutation plots.
Highly correlated genes for METTL25:
Showing top 20/523 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| METTL25 | ZNF85 | 0.703839 | 3 | 0 | 3 |
| METTL25 | ZNF43 | 0.679109 | 3 | 0 | 3 |
| METTL25 | KDM4B | 0.673698 | 3 | 0 | 3 |
| METTL25 | C12orf29 | 0.673239 | 4 | 0 | 3 |
| METTL25 | ZNF44 | 0.669611 | 3 | 0 | 3 |
| METTL25 | ATP6V1F | 0.668372 | 3 | 0 | 3 |
| METTL25 | MSRA | 0.665812 | 5 | 0 | 5 |
| METTL25 | TMTC2 | 0.665748 | 4 | 0 | 4 |
| METTL25 | ZFAND2B | 0.662819 | 4 | 0 | 4 |
| METTL25 | FAM149B1 | 0.661716 | 4 | 0 | 4 |
| METTL25 | MRPL54 | 0.655925 | 5 | 0 | 3 |
| METTL25 | FAM120C | 0.651985 | 3 | 0 | 3 |
| METTL25 | TMBIM4 | 0.651119 | 5 | 0 | 4 |
| METTL25 | PPOX | 0.649721 | 3 | 0 | 3 |
| METTL25 | GSTK1 | 0.647255 | 4 | 0 | 3 |
| METTL25 | NAAA | 0.646544 | 5 | 0 | 4 |
| METTL25 | AKR1A1 | 0.645729 | 6 | 0 | 5 |
| METTL25 | KDM4C | 0.644792 | 5 | 0 | 4 |
| METTL25 | MKRN2 | 0.642737 | 4 | 0 | 3 |
| METTL25 | SRSF8 | 0.64177 | 3 | 0 | 3 |
For details and further investigation, click here
