ZNF85

 

Full name: zinc finger protein 85 Alias Symbol: HPF4|HTF1
Type: protein-coding gene Cytoband: 19p12
Entrez ID: 7639 HGNC ID: HGNC:13160 Ensembl Gene: ENSG00000105750 OMIM ID: 603899
Drug and gene relationship at DGIdb

 

Expression of ZNF85:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ZNF85 7639 206572_x_at -0.4924 0.3496
GSE20347 ZNF85 7639 206572_x_at -0.4317 0.0278
GSE23400 ZNF85 7639 206572_x_at -0.1715 0.0000
GSE26886 ZNF85 7639 206572_x_at -0.3966 0.0677
GSE29001 ZNF85 7639 206572_x_at -0.5143 0.0590
GSE38129 ZNF85 7639 206572_x_at -0.6157 0.0004
GSE45670 ZNF85 7639 206572_x_at -0.8153 0.0003
GSE53622 ZNF85 7639 18699 -0.2577 0.0008
GSE53624 ZNF85 7639 18699 -0.2484 0.0004
GSE63941 ZNF85 7639 1554445_at -1.6993 0.0183
GSE77861 ZNF85 7639 206572_x_at -0.5885 0.1711
GSE97050 ZNF85 7639 A_23_P67702 -0.1922 0.6046
SRP007169 ZNF85 7639 RNAseq -1.2775 0.0157
SRP008496 ZNF85 7639 RNAseq -1.1305 0.0038
SRP064894 ZNF85 7639 RNAseq -0.2141 0.4929
SRP133303 ZNF85 7639 RNAseq -0.5939 0.0270
SRP159526 ZNF85 7639 RNAseq -0.7731 0.1504
SRP193095 ZNF85 7639 RNAseq -0.9552 0.0000
SRP219564 ZNF85 7639 RNAseq -0.7808 0.1642
TCGA ZNF85 7639 RNAseq -0.8334 0.0006

Upregulated datasets: 0; Downregulated datasets: 3.  


 

Survival by ZNF85 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ZNF85:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ZNF85 7639 3 5 22
GSE20123 ZNF85 7639 3 3 24
GSE43470 ZNF85 7639 2 6 35
GSE46452 ZNF85 7639 47 1 11
GSE47630 ZNF85 7639 7 7 26
GSE54993 ZNF85 7639 17 3 50
GSE54994 ZNF85 7639 6 13 34
GSE60625 ZNF85 7639 9 0 2
GSE74703 ZNF85 7639 2 4 30
GSE74704 ZNF85 7639 0 3 17
TCGA ZNF85 7639 16 12 68

Total number of gains: 112; Total number of losses: 57; Total Number of normals: 319.  


 

Somatic mutations of ZNF85:

 

Generating mutation plots.

 

Highly correlated genes for ZNF85:

 

Showing top 20/368 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ZNF85ZNF7290.850257303
ZNF85NIPSNAP3A0.777838303
ZNF85ZNF430.7566341009
ZNF85ZNF7280.754491303
ZNF85ZNF4790.750005303
ZNF85METTL250.703839303
ZNF85RNF1250.697974404
ZNF85ZNF6750.693012908
ZNF85ZNF930.6896881009
ZNF85ZNF8230.689526404
ZNF85ZNF4860.681755504
ZNF85ZNF2530.6803931109
ZNF85TRAPPC80.679144707
ZNF85FAM221A0.677128504
ZNF85A2ML10.667499303
ZNF85SPCS10.666201303
ZNF85ZNF6650.665646807
ZNF85GNL30.664039303
ZNF85ZNF990.662692403
ZNF85ZNF7380.659295705

For details and further investigation, click here