| Full name: cAMP-dependent protein kinase inhibitor gamma | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 20q13.12 | ||
| Entrez ID: 11142 | HGNC ID: HGNC:9019 | Ensembl Gene: ENSG00000168734 | OMIM ID: 604932 |
| Drug and gene relationship at DGIdb | |||
Expression of PKIG:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PKIG | 11142 | 202732_at | -0.5342 | 0.6166 | |
| GSE20347 | PKIG | 11142 | 202732_at | 0.1872 | 0.6069 | |
| GSE23400 | PKIG | 11142 | 202732_at | -0.3291 | 0.0279 | |
| GSE26886 | PKIG | 11142 | 202732_at | 2.5665 | 0.0000 | |
| GSE29001 | PKIG | 11142 | 202732_at | 0.0260 | 0.9657 | |
| GSE38129 | PKIG | 11142 | 202732_at | -0.2718 | 0.5855 | |
| GSE45670 | PKIG | 11142 | 202732_at | -1.4416 | 0.0001 | |
| GSE53622 | PKIG | 11142 | 92394 | -0.6366 | 0.0000 | |
| GSE53624 | PKIG | 11142 | 92394 | -0.5756 | 0.0000 | |
| GSE63941 | PKIG | 11142 | 202732_at | -2.3796 | 0.0135 | |
| GSE77861 | PKIG | 11142 | 202732_at | 1.3463 | 0.0055 | |
| GSE97050 | PKIG | 11142 | A_23_P91221 | -0.4369 | 0.2230 | |
| SRP007169 | PKIG | 11142 | RNAseq | 1.0638 | 0.0663 | |
| SRP008496 | PKIG | 11142 | RNAseq | 1.6405 | 0.0002 | |
| SRP064894 | PKIG | 11142 | RNAseq | -0.0692 | 0.8449 | |
| SRP133303 | PKIG | 11142 | RNAseq | 0.0361 | 0.9197 | |
| SRP159526 | PKIG | 11142 | RNAseq | -0.0051 | 0.9910 | |
| SRP193095 | PKIG | 11142 | RNAseq | 0.8558 | 0.0001 | |
| SRP219564 | PKIG | 11142 | RNAseq | -1.0513 | 0.2746 | |
| TCGA | PKIG | 11142 | RNAseq | -0.2279 | 0.0205 |
Upregulated datasets: 3; Downregulated datasets: 2.
Survival by PKIG expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PKIG:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PKIG | 11142 | 13 | 1 | 16 | |
| GSE20123 | PKIG | 11142 | 13 | 1 | 16 | |
| GSE43470 | PKIG | 11142 | 12 | 2 | 29 | |
| GSE46452 | PKIG | 11142 | 29 | 0 | 30 | |
| GSE47630 | PKIG | 11142 | 24 | 1 | 15 | |
| GSE54993 | PKIG | 11142 | 0 | 17 | 53 | |
| GSE54994 | PKIG | 11142 | 25 | 0 | 28 | |
| GSE60625 | PKIG | 11142 | 0 | 0 | 11 | |
| GSE74703 | PKIG | 11142 | 10 | 2 | 24 | |
| GSE74704 | PKIG | 11142 | 9 | 0 | 11 | |
| TCGA | PKIG | 11142 | 46 | 3 | 47 |
Total number of gains: 181; Total number of losses: 27; Total Number of normals: 280.
Somatic mutations of PKIG:
Generating mutation plots.
Highly correlated genes for PKIG:
Showing top 20/1500 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PKIG | TP53I13 | 0.837617 | 3 | 0 | 3 |
| PKIG | SLC25A32 | 0.836614 | 3 | 0 | 3 |
| PKIG | TMED8 | 0.8348 | 3 | 0 | 3 |
| PKIG | TCEAL6 | 0.829466 | 3 | 0 | 3 |
| PKIG | NCOR2 | 0.81792 | 4 | 0 | 4 |
| PKIG | ZEB1 | 0.815987 | 3 | 0 | 3 |
| PKIG | WDR81 | 0.814337 | 3 | 0 | 3 |
| PKIG | MAPKAPK5 | 0.81373 | 3 | 0 | 3 |
| PKIG | LNP1 | 0.81251 | 3 | 0 | 3 |
| PKIG | KHSRP | 0.810495 | 3 | 0 | 3 |
| PKIG | ZBED1 | 0.80922 | 3 | 0 | 3 |
| PKIG | CBLB | 0.805829 | 3 | 0 | 3 |
| PKIG | PTK2 | 0.798438 | 3 | 0 | 3 |
| PKIG | BAZ1B | 0.797353 | 3 | 0 | 3 |
| PKIG | ZCCHC3 | 0.796516 | 3 | 0 | 3 |
| PKIG | MCAM | 0.792731 | 9 | 0 | 9 |
| PKIG | DNM1L | 0.79036 | 3 | 0 | 3 |
| PKIG | TGFB1I1 | 0.78858 | 11 | 0 | 11 |
| PKIG | ANXA6 | 0.788422 | 12 | 0 | 11 |
| PKIG | HIP1 | 0.782771 | 4 | 0 | 4 |
For details and further investigation, click here
