| Full name: keratin associated protein 21-2 | Alias Symbol: KAP21.2 | ||
| Type: protein-coding gene | Cytoband: 21q22.11 | ||
| Entrez ID: 337978 | HGNC ID: HGNC:18946 | Ensembl Gene: ENSG00000187026 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of KRTAP21-2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | KRTAP21-2 | 337978 | 92462 | -0.2063 | 0.0458 | |
| GSE53624 | KRTAP21-2 | 337978 | 92462 | -0.3825 | 0.0223 | |
| GSE97050 | KRTAP21-2 | 337978 | A_33_P3388061 | -0.0519 | 0.8285 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KRTAP21-2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRTAP21-2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRTAP21-2 | 337978 | 2 | 9 | 19 | |
| GSE20123 | KRTAP21-2 | 337978 | 2 | 9 | 19 | |
| GSE43470 | KRTAP21-2 | 337978 | 2 | 9 | 32 | |
| GSE46452 | KRTAP21-2 | 337978 | 1 | 21 | 37 | |
| GSE47630 | KRTAP21-2 | 337978 | 6 | 17 | 17 | |
| GSE54993 | KRTAP21-2 | 337978 | 9 | 1 | 60 | |
| GSE54994 | KRTAP21-2 | 337978 | 1 | 9 | 43 | |
| GSE60625 | KRTAP21-2 | 337978 | 0 | 0 | 11 | |
| GSE74703 | KRTAP21-2 | 337978 | 2 | 6 | 28 | |
| GSE74704 | KRTAP21-2 | 337978 | 2 | 6 | 12 |
Total number of gains: 27; Total number of losses: 87; Total Number of normals: 278.
Somatic mutations of KRTAP21-2:
Generating mutation plots.
Highly correlated genes for KRTAP21-2:
Showing top 20/51 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRTAP21-2 | PRSS36 | 0.801538 | 3 | 0 | 3 |
| KRTAP21-2 | SFTPA2 | 0.8013 | 3 | 0 | 3 |
| KRTAP21-2 | SPSB4 | 0.780124 | 3 | 0 | 3 |
| KRTAP21-2 | KRTAP19-2 | 0.75033 | 3 | 0 | 3 |
| KRTAP21-2 | ELFN1 | 0.741138 | 3 | 0 | 3 |
| KRTAP21-2 | ZNF461 | 0.734837 | 3 | 0 | 3 |
| KRTAP21-2 | SLC38A7 | 0.734656 | 3 | 0 | 3 |
| KRTAP21-2 | ZNF416 | 0.728199 | 3 | 0 | 3 |
| KRTAP21-2 | SMPD1 | 0.726436 | 3 | 0 | 3 |
| KRTAP21-2 | WWOX | 0.7256 | 3 | 0 | 3 |
| KRTAP21-2 | TMEM53 | 0.720488 | 3 | 0 | 3 |
| KRTAP21-2 | DEFB132 | 0.718782 | 3 | 0 | 3 |
| KRTAP21-2 | CCIN | 0.714524 | 3 | 0 | 3 |
| KRTAP21-2 | TMEM150A | 0.706697 | 3 | 0 | 3 |
| KRTAP21-2 | ZNF878 | 0.704655 | 3 | 0 | 3 |
| KRTAP21-2 | ZNF547 | 0.701036 | 3 | 0 | 3 |
| KRTAP21-2 | SLC11A1 | 0.700349 | 3 | 0 | 3 |
| KRTAP21-2 | APOBEC2 | 0.698847 | 3 | 0 | 3 |
| KRTAP21-2 | KRTAP9-6 | 0.690263 | 3 | 0 | 3 |
| KRTAP21-2 | KRT81 | 0.688869 | 3 | 0 | 3 |
For details and further investigation, click here
