| Full name: ring finger and CCCH-type domains 1 | Alias Symbol: KIAA2025|roquin|RP5-1198E17.5|RNF198 | ||
| Type: protein-coding gene | Cytoband: 1q25.1 | ||
| Entrez ID: 149041 | HGNC ID: HGNC:29434 | Ensembl Gene: ENSG00000135870 | OMIM ID: 609424 |
| Drug and gene relationship at DGIdb | |||
Expression of RC3H1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RC3H1 | 149041 | 225893_at | -0.1754 | 0.3617 | |
| GSE20347 | RC3H1 | 149041 | 215109_at | -0.1157 | 0.3358 | |
| GSE23400 | RC3H1 | 149041 | 215109_at | -0.0971 | 0.0008 | |
| GSE26886 | RC3H1 | 149041 | 225893_at | -0.4124 | 0.0474 | |
| GSE29001 | RC3H1 | 149041 | 215109_at | -0.0606 | 0.8191 | |
| GSE38129 | RC3H1 | 149041 | 215109_at | -0.0986 | 0.4023 | |
| GSE45670 | RC3H1 | 149041 | 225893_at | -0.1178 | 0.3205 | |
| GSE53622 | RC3H1 | 149041 | 15978 | -0.4533 | 0.0000 | |
| GSE53624 | RC3H1 | 149041 | 15978 | -0.5159 | 0.0000 | |
| GSE63941 | RC3H1 | 149041 | 225893_at | -1.1238 | 0.0050 | |
| GSE77861 | RC3H1 | 149041 | 225893_at | 0.2363 | 0.2923 | |
| GSE97050 | RC3H1 | 149041 | A_33_P3288774 | -0.3799 | 0.1872 | |
| SRP007169 | RC3H1 | 149041 | RNAseq | -0.6245 | 0.0410 | |
| SRP008496 | RC3H1 | 149041 | RNAseq | -0.4718 | 0.0008 | |
| SRP064894 | RC3H1 | 149041 | RNAseq | -0.8920 | 0.0000 | |
| SRP133303 | RC3H1 | 149041 | RNAseq | -0.2889 | 0.0026 | |
| SRP159526 | RC3H1 | 149041 | RNAseq | -0.5033 | 0.0213 | |
| SRP193095 | RC3H1 | 149041 | RNAseq | -0.4960 | 0.0000 | |
| SRP219564 | RC3H1 | 149041 | RNAseq | -0.4587 | 0.0093 | |
| TCGA | RC3H1 | 149041 | RNAseq | -0.1174 | 0.0105 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by RC3H1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RC3H1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RC3H1 | 149041 | 12 | 0 | 18 | |
| GSE20123 | RC3H1 | 149041 | 12 | 0 | 18 | |
| GSE43470 | RC3H1 | 149041 | 7 | 2 | 34 | |
| GSE46452 | RC3H1 | 149041 | 3 | 1 | 55 | |
| GSE47630 | RC3H1 | 149041 | 14 | 0 | 26 | |
| GSE54993 | RC3H1 | 149041 | 0 | 6 | 64 | |
| GSE54994 | RC3H1 | 149041 | 15 | 0 | 38 | |
| GSE60625 | RC3H1 | 149041 | 0 | 0 | 11 | |
| GSE74703 | RC3H1 | 149041 | 7 | 2 | 27 | |
| GSE74704 | RC3H1 | 149041 | 5 | 0 | 15 | |
| TCGA | RC3H1 | 149041 | 42 | 3 | 51 |
Total number of gains: 117; Total number of losses: 14; Total Number of normals: 357.
Somatic mutations of RC3H1:
Generating mutation plots.
Highly correlated genes for RC3H1:
Showing top 20/479 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RC3H1 | ALKBH7 | 0.790074 | 3 | 0 | 3 |
| RC3H1 | PINK1 | 0.77422 | 4 | 0 | 4 |
| RC3H1 | IK | 0.737504 | 3 | 0 | 3 |
| RC3H1 | ZNF461 | 0.735808 | 3 | 0 | 3 |
| RC3H1 | CCNYL1 | 0.724315 | 3 | 0 | 3 |
| RC3H1 | NCOA4 | 0.719719 | 4 | 0 | 4 |
| RC3H1 | KLHDC8B | 0.717427 | 3 | 0 | 3 |
| RC3H1 | ESYT2 | 0.714881 | 4 | 0 | 4 |
| RC3H1 | ZMAT3 | 0.714379 | 3 | 0 | 3 |
| RC3H1 | PRADC1 | 0.713771 | 4 | 0 | 3 |
| RC3H1 | STK40 | 0.709054 | 3 | 0 | 3 |
| RC3H1 | TRIM8 | 0.706458 | 3 | 0 | 3 |
| RC3H1 | SIKE1 | 0.703405 | 3 | 0 | 3 |
| RC3H1 | TMEM50A | 0.700307 | 3 | 0 | 3 |
| RC3H1 | PPM1L | 0.698882 | 4 | 0 | 4 |
| RC3H1 | BACH1 | 0.696373 | 4 | 0 | 4 |
| RC3H1 | ZNF776 | 0.69256 | 3 | 0 | 3 |
| RC3H1 | CNOT4 | 0.691365 | 5 | 0 | 5 |
| RC3H1 | RHBDD1 | 0.691334 | 4 | 0 | 4 |
| RC3H1 | PRDM15 | 0.691131 | 3 | 0 | 3 |
For details and further investigation, click here
