| Full name: cytochrome P450 family 11 subfamily B member 1 | Alias Symbol: P450C11|FHI|CPN1 | ||
| Type: protein-coding gene | Cytoband: 8q24.3 | ||
| Entrez ID: 1584 | HGNC ID: HGNC:2591 | Ensembl Gene: ENSG00000160882 | OMIM ID: 610613 |
| Drug and gene relationship at DGIdb | |||
Expression of CYP11B1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CYP11B1 | 1584 | 1552493_s_at | 0.0212 | 0.9529 | |
| GSE20347 | CYP11B1 | 1584 | 214610_at | 0.0318 | 0.6405 | |
| GSE23400 | CYP11B1 | 1584 | 214610_at | -0.1163 | 0.0001 | |
| GSE26886 | CYP11B1 | 1584 | 1552493_s_at | 0.2783 | 0.0034 | |
| GSE29001 | CYP11B1 | 1584 | 214610_at | -0.1161 | 0.4798 | |
| GSE38129 | CYP11B1 | 1584 | 214610_at | -0.0505 | 0.3830 | |
| GSE45670 | CYP11B1 | 1584 | 1552493_s_at | 0.0285 | 0.7540 | |
| GSE53622 | CYP11B1 | 1584 | 110877 | 0.7139 | 0.0000 | |
| GSE53624 | CYP11B1 | 1584 | 110877 | 0.4202 | 0.0000 | |
| GSE63941 | CYP11B1 | 1584 | 1552493_s_at | 0.2225 | 0.1142 | |
| GSE77861 | CYP11B1 | 1584 | 1552493_s_at | -0.0664 | 0.5317 | |
| GSE97050 | CYP11B1 | 1584 | A_24_P329424 | 0.1950 | 0.3037 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CYP11B1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CYP11B1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CYP11B1 | 1584 | 16 | 1 | 13 | |
| GSE20123 | CYP11B1 | 1584 | 17 | 1 | 12 | |
| GSE43470 | CYP11B1 | 1584 | 17 | 2 | 24 | |
| GSE46452 | CYP11B1 | 1584 | 27 | 0 | 32 | |
| GSE47630 | CYP11B1 | 1584 | 23 | 1 | 16 | |
| GSE54993 | CYP11B1 | 1584 | 0 | 25 | 45 | |
| GSE54994 | CYP11B1 | 1584 | 39 | 1 | 13 | |
| GSE60625 | CYP11B1 | 1584 | 3 | 4 | 4 | |
| GSE74703 | CYP11B1 | 1584 | 15 | 1 | 20 | |
| GSE74704 | CYP11B1 | 1584 | 10 | 0 | 10 | |
| TCGA | CYP11B1 | 1584 | 64 | 2 | 30 |
Total number of gains: 231; Total number of losses: 38; Total Number of normals: 219.
Somatic mutations of CYP11B1:
Generating mutation plots.
Highly correlated genes for CYP11B1:
Showing top 20/1070 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CYP11B1 | STK11 | 0.784708 | 3 | 0 | 3 |
| CYP11B1 | ZGLP1 | 0.773523 | 3 | 0 | 3 |
| CYP11B1 | BSND | 0.767282 | 4 | 0 | 4 |
| CYP11B1 | HSD17B14 | 0.753885 | 3 | 0 | 3 |
| CYP11B1 | PFN3 | 0.745428 | 3 | 0 | 3 |
| CYP11B1 | TEKT2 | 0.738702 | 4 | 0 | 4 |
| CYP11B1 | SPATA2L | 0.738448 | 3 | 0 | 3 |
| CYP11B1 | GPD1 | 0.732635 | 5 | 0 | 5 |
| CYP11B1 | C1QTNF6 | 0.732361 | 3 | 0 | 3 |
| CYP11B1 | ACRV1 | 0.732089 | 5 | 0 | 5 |
| CYP11B1 | SULT1C3 | 0.732076 | 3 | 0 | 3 |
| CYP11B1 | MS4A18 | 0.723796 | 3 | 0 | 3 |
| CYP11B1 | KLHDC4 | 0.721715 | 3 | 0 | 3 |
| CYP11B1 | HECW1 | 0.72045 | 7 | 0 | 6 |
| CYP11B1 | ITGA10 | 0.715679 | 6 | 0 | 5 |
| CYP11B1 | FSCN3 | 0.715444 | 6 | 0 | 6 |
| CYP11B1 | LRRC10 | 0.712686 | 3 | 0 | 3 |
| CYP11B1 | ASTN2 | 0.709571 | 3 | 0 | 3 |
| CYP11B1 | IFT122 | 0.708856 | 3 | 0 | 3 |
| CYP11B1 | ARHGEF38 | 0.708023 | 5 | 0 | 5 |
For details and further investigation, click here
