| Full name: killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2 | Alias Symbol: cl-49|nkat5|183ActI|CD158J | ||
| Type: protein-coding gene | Cytoband: 19q13.4 alternate reference locus | ||
| Entrez ID: 100132285 | HGNC ID: HGNC:6334 | Ensembl Gene: | OMIM ID: 604953 |
| Drug and gene relationship at DGIdb | |||
KIR2DS2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04612 | Antigen processing and presentation | |
| hsa04650 | Natural killer cell mediated cytotoxicity |
Expression of KIR2DS2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KIR2DS2 | 100132285 | 211532_x_at | 0.0088 | 0.9813 | |
| GSE20347 | KIR2DS2 | 100132285 | 211532_x_at | -0.1101 | 0.3194 | |
| GSE23400 | KIR2DS2 | 100132285 | 211532_x_at | -0.1140 | 0.0115 | |
| GSE26886 | KIR2DS2 | 100132285 | 211532_x_at | 0.1225 | 0.2359 | |
| GSE29001 | KIR2DS2 | 100132285 | 211532_x_at | -0.3118 | 0.0835 | |
| GSE38129 | KIR2DS2 | 100132285 | 211532_x_at | -0.1615 | 0.0987 | |
| GSE45670 | KIR2DS2 | 100132285 | 211532_x_at | -0.1065 | 0.1463 | |
| GSE63941 | KIR2DS2 | 100132285 | 211532_x_at | 0.0852 | 0.6825 | |
| GSE77861 | KIR2DS2 | 100132285 | 211532_x_at | -0.0761 | 0.6178 | |
| GSE97050 | KIR2DS2 | 100132285 | A_23_P130815 | 0.2315 | 0.6500 |
Upregulated datasets: 0; Downregulated datasets: 0.
Copy number change of KIR2DS2:
No record found for this gene.
Somatic mutations of KIR2DS2:
Generating mutation plots.
Highly correlated genes for KIR2DS2:
Showing top 20/1080 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KIR2DS2 | MYH8 | 0.759248 | 3 | 0 | 3 |
| KIR2DS2 | LALBA | 0.759246 | 4 | 0 | 4 |
| KIR2DS2 | IFNA17 | 0.752901 | 4 | 0 | 4 |
| KIR2DS2 | CPNE6 | 0.752626 | 3 | 0 | 3 |
| KIR2DS2 | FOLH1 | 0.745896 | 5 | 0 | 5 |
| KIR2DS2 | SLC5A7 | 0.74182 | 4 | 0 | 4 |
| KIR2DS2 | IL1RAPL2 | 0.740548 | 6 | 0 | 5 |
| KIR2DS2 | CRHR2 | 0.730043 | 6 | 0 | 6 |
| KIR2DS2 | CGA | 0.725225 | 6 | 0 | 6 |
| KIR2DS2 | CHRM2 | 0.721786 | 5 | 0 | 5 |
| KIR2DS2 | HRC | 0.719678 | 4 | 0 | 4 |
| KIR2DS2 | ACRV1 | 0.719332 | 5 | 0 | 5 |
| KIR2DS2 | BMP15 | 0.719169 | 6 | 0 | 6 |
| KIR2DS2 | OR6A2 | 0.717138 | 6 | 0 | 6 |
| KIR2DS2 | PHF7 | 0.715884 | 5 | 0 | 4 |
| KIR2DS2 | TSHB | 0.715694 | 4 | 0 | 4 |
| KIR2DS2 | SULT2A1 | 0.71527 | 3 | 0 | 3 |
| KIR2DS2 | SLC5A5 | 0.714017 | 5 | 0 | 5 |
| KIR2DS2 | SLC6A5 | 0.712966 | 4 | 0 | 4 |
| KIR2DS2 | RNF17 | 0.710335 | 4 | 0 | 4 |
For details and further investigation, click here
