| Full name: adenosine deaminase domain containing 1 | Alias Symbol: Tenr | ||
| Type: protein-coding gene | Cytoband: 4q27 | ||
| Entrez ID: 132612 | HGNC ID: HGNC:30713 | Ensembl Gene: ENSG00000164113 | OMIM ID: 614130 |
| Drug and gene relationship at DGIdb | |||
Expression of ADAD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ADAD1 | 132612 | 231448_at | 0.0929 | 0.7360 | |
| GSE26886 | ADAD1 | 132612 | 231448_at | -0.2522 | 0.0569 | |
| GSE45670 | ADAD1 | 132612 | 231448_at | -0.1931 | 0.0990 | |
| GSE53622 | ADAD1 | 132612 | 12271 | -0.0476 | 0.6751 | |
| GSE53624 | ADAD1 | 132612 | 12271 | -0.5642 | 0.0000 | |
| GSE63941 | ADAD1 | 132612 | 231448_at | 0.1939 | 0.0830 | |
| GSE77861 | ADAD1 | 132612 | 231448_at | -0.0575 | 0.6553 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ADAD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ADAD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ADAD1 | 132612 | 1 | 13 | 16 | |
| GSE20123 | ADAD1 | 132612 | 1 | 13 | 16 | |
| GSE43470 | ADAD1 | 132612 | 0 | 13 | 30 | |
| GSE46452 | ADAD1 | 132612 | 1 | 36 | 22 | |
| GSE47630 | ADAD1 | 132612 | 0 | 22 | 18 | |
| GSE54993 | ADAD1 | 132612 | 9 | 0 | 61 | |
| GSE54994 | ADAD1 | 132612 | 1 | 10 | 42 | |
| GSE60625 | ADAD1 | 132612 | 0 | 1 | 10 | |
| GSE74703 | ADAD1 | 132612 | 0 | 11 | 25 | |
| GSE74704 | ADAD1 | 132612 | 0 | 7 | 13 | |
| TCGA | ADAD1 | 132612 | 8 | 35 | 53 |
Total number of gains: 21; Total number of losses: 161; Total Number of normals: 306.
Somatic mutations of ADAD1:
Generating mutation plots.
Highly correlated genes for ADAD1:
Showing top 20/41 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ADAD1 | MORF4L2-AS1 | 0.716482 | 3 | 0 | 3 |
| ADAD1 | KLLN | 0.674238 | 4 | 0 | 4 |
| ADAD1 | KCNA4 | 0.661313 | 3 | 0 | 3 |
| ADAD1 | ANHX | 0.640777 | 4 | 0 | 4 |
| ADAD1 | ABCA4 | 0.637618 | 4 | 0 | 3 |
| ADAD1 | ASB12 | 0.637106 | 4 | 0 | 3 |
| ADAD1 | SLC4A1 | 0.635271 | 3 | 0 | 3 |
| ADAD1 | RBP5 | 0.632951 | 3 | 0 | 3 |
| ADAD1 | UNC79 | 0.629688 | 5 | 0 | 4 |
| ADAD1 | IL17RC | 0.627707 | 3 | 0 | 3 |
| ADAD1 | CD300LG | 0.614009 | 3 | 0 | 3 |
| ADAD1 | DGCR12 | 0.609137 | 3 | 0 | 3 |
| ADAD1 | CCDC116 | 0.604271 | 3 | 0 | 3 |
| ADAD1 | GAB4 | 0.602693 | 4 | 0 | 3 |
| ADAD1 | CACNA1G | 0.600481 | 4 | 0 | 4 |
| ADAD1 | VWA3A | 0.597339 | 5 | 0 | 4 |
| ADAD1 | LINC00092 | 0.595913 | 3 | 0 | 3 |
| ADAD1 | GBP6 | 0.59195 | 3 | 0 | 3 |
| ADAD1 | CLRN1 | 0.589872 | 4 | 0 | 3 |
| ADAD1 | DGKK | 0.580375 | 3 | 0 | 3 |
For details and further investigation, click here
