| Full name: interleukin 17 receptor C | Alias Symbol: IL17-RL | ||
| Type: protein-coding gene | Cytoband: 3p25.3 | ||
| Entrez ID: 84818 | HGNC ID: HGNC:18358 | Ensembl Gene: ENSG00000163702 | OMIM ID: 610925 |
| Drug and gene relationship at DGIdb | |||
Expression of IL17RC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IL17RC | 84818 | 64440_at | -0.4911 | 0.0643 | |
| GSE20347 | IL17RC | 84818 | 64440_at | -0.5105 | 0.0000 | |
| GSE23400 | IL17RC | 84818 | 64440_at | -0.5221 | 0.0000 | |
| GSE26886 | IL17RC | 84818 | 64440_at | -0.7456 | 0.0001 | |
| GSE29001 | IL17RC | 84818 | 64440_at | -0.2991 | 0.0702 | |
| GSE38129 | IL17RC | 84818 | 64440_at | -0.6065 | 0.0000 | |
| GSE45670 | IL17RC | 84818 | 64440_at | -0.1949 | 0.0976 | |
| GSE53622 | IL17RC | 84818 | 16619 | -1.1630 | 0.0000 | |
| GSE53624 | IL17RC | 84818 | 158160 | -0.3615 | 0.0000 | |
| GSE63941 | IL17RC | 84818 | 64440_at | 0.8175 | 0.0018 | |
| GSE77861 | IL17RC | 84818 | 64440_at | -0.3660 | 0.0035 | |
| GSE97050 | IL17RC | 84818 | A_23_P166775 | -0.0890 | 0.7192 | |
| SRP007169 | IL17RC | 84818 | RNAseq | -2.3887 | 0.0001 | |
| SRP008496 | IL17RC | 84818 | RNAseq | -2.3474 | 0.0000 | |
| SRP064894 | IL17RC | 84818 | RNAseq | -0.8872 | 0.0005 | |
| SRP133303 | IL17RC | 84818 | RNAseq | -1.2800 | 0.0000 | |
| SRP159526 | IL17RC | 84818 | RNAseq | -1.1672 | 0.0001 | |
| SRP193095 | IL17RC | 84818 | RNAseq | -1.1604 | 0.0000 | |
| SRP219564 | IL17RC | 84818 | RNAseq | -0.6617 | 0.1086 | |
| TCGA | IL17RC | 84818 | RNAseq | -0.2642 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by IL17RC expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IL17RC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IL17RC | 84818 | 1 | 18 | 11 | |
| GSE20123 | IL17RC | 84818 | 1 | 18 | 11 | |
| GSE43470 | IL17RC | 84818 | 1 | 20 | 22 | |
| GSE46452 | IL17RC | 84818 | 2 | 17 | 40 | |
| GSE47630 | IL17RC | 84818 | 2 | 23 | 15 | |
| GSE54993 | IL17RC | 84818 | 6 | 1 | 63 | |
| GSE54994 | IL17RC | 84818 | 3 | 31 | 19 | |
| GSE60625 | IL17RC | 84818 | 5 | 0 | 6 | |
| GSE74703 | IL17RC | 84818 | 1 | 16 | 19 | |
| GSE74704 | IL17RC | 84818 | 1 | 11 | 8 | |
| TCGA | IL17RC | 84818 | 5 | 65 | 26 |
Total number of gains: 28; Total number of losses: 220; Total Number of normals: 240.
Somatic mutations of IL17RC:
Generating mutation plots.
Highly correlated genes for IL17RC:
Showing top 20/1346 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IL17RC | MAPK3 | 0.827985 | 9 | 0 | 9 |
| IL17RC | MFSD2B | 0.798926 | 3 | 0 | 3 |
| IL17RC | KBTBD13 | 0.785029 | 3 | 0 | 3 |
| IL17RC | PADI1 | 0.781081 | 9 | 0 | 9 |
| IL17RC | OR51T1 | 0.778217 | 3 | 0 | 3 |
| IL17RC | OR10G3 | 0.768768 | 3 | 0 | 3 |
| IL17RC | C10orf90 | 0.763891 | 3 | 0 | 3 |
| IL17RC | SNORA68 | 0.756199 | 4 | 0 | 4 |
| IL17RC | FNDC9 | 0.755362 | 3 | 0 | 3 |
| IL17RC | SLC13A4 | 0.752289 | 11 | 0 | 11 |
| IL17RC | CST11 | 0.752223 | 4 | 0 | 4 |
| IL17RC | KRTAP20-1 | 0.748046 | 3 | 0 | 3 |
| IL17RC | PRSS3 | 0.74641 | 9 | 0 | 9 |
| IL17RC | GALR3 | 0.745894 | 11 | 0 | 10 |
| IL17RC | OR2Z1 | 0.745768 | 3 | 0 | 3 |
| IL17RC | TPRX1 | 0.745458 | 3 | 0 | 3 |
| IL17RC | BBOX1 | 0.743807 | 9 | 0 | 9 |
| IL17RC | FAM163B | 0.742324 | 3 | 0 | 3 |
| IL17RC | GPR78 | 0.737947 | 3 | 0 | 3 |
| IL17RC | RARG | 0.737394 | 11 | 0 | 10 |
For details and further investigation, click here
