| Full name: coiled-coil domain containing 116 | Alias Symbol: FLJ36046 | ||
| Type: protein-coding gene | Cytoband: 22q11.21 | ||
| Entrez ID: 164592 | HGNC ID: HGNC:26688 | Ensembl Gene: ENSG00000161180 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC116:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC116 | 164592 | 1555792_a_at | -0.1382 | 0.6309 | |
| GSE26886 | CCDC116 | 164592 | 1555792_a_at | -0.2329 | 0.1057 | |
| GSE45670 | CCDC116 | 164592 | 1555792_a_at | -0.0354 | 0.7899 | |
| GSE53622 | CCDC116 | 164592 | 78003 | -0.5234 | 0.0000 | |
| GSE53624 | CCDC116 | 164592 | 78003 | -0.4627 | 0.0001 | |
| GSE63941 | CCDC116 | 164592 | 1555792_a_at | 0.1392 | 0.2241 | |
| GSE77861 | CCDC116 | 164592 | 1555792_a_at | -0.2437 | 0.0487 | |
| TCGA | CCDC116 | 164592 | RNAseq | -0.0301 | 0.9197 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CCDC116 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC116:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC116 | 164592 | 5 | 7 | 18 | |
| GSE20123 | CCDC116 | 164592 | 5 | 7 | 18 | |
| GSE43470 | CCDC116 | 164592 | 3 | 7 | 33 | |
| GSE46452 | CCDC116 | 164592 | 33 | 1 | 25 | |
| GSE47630 | CCDC116 | 164592 | 8 | 5 | 27 | |
| GSE54993 | CCDC116 | 164592 | 3 | 6 | 61 | |
| GSE54994 | CCDC116 | 164592 | 11 | 7 | 35 | |
| GSE60625 | CCDC116 | 164592 | 5 | 0 | 6 | |
| GSE74703 | CCDC116 | 164592 | 3 | 5 | 28 | |
| GSE74704 | CCDC116 | 164592 | 2 | 4 | 14 | |
| TCGA | CCDC116 | 164592 | 27 | 17 | 52 |
Total number of gains: 105; Total number of losses: 66; Total Number of normals: 317.
Somatic mutations of CCDC116:
Generating mutation plots.
Highly correlated genes for CCDC116:
Showing top 20/238 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC116 | GJD2 | 0.700266 | 3 | 0 | 3 |
| CCDC116 | LINC00868 | 0.676323 | 4 | 0 | 4 |
| CCDC116 | OPRD1 | 0.671602 | 3 | 0 | 3 |
| CCDC116 | TXNDC2 | 0.670459 | 3 | 0 | 3 |
| CCDC116 | ARHGEF25 | 0.669657 | 3 | 0 | 3 |
| CCDC116 | THRSP | 0.668888 | 4 | 0 | 4 |
| CCDC116 | SPATA3-AS1 | 0.66528 | 3 | 0 | 3 |
| CCDC116 | SPTBN2 | 0.664649 | 3 | 0 | 3 |
| CCDC116 | F11 | 0.663993 | 3 | 0 | 3 |
| CCDC116 | FGF21 | 0.663942 | 3 | 0 | 3 |
| CCDC116 | NKD1 | 0.663378 | 4 | 0 | 4 |
| CCDC116 | EXOC3L2 | 0.650791 | 3 | 0 | 3 |
| CCDC116 | TMEM114 | 0.649692 | 4 | 0 | 3 |
| CCDC116 | CKM | 0.642166 | 3 | 0 | 3 |
| CCDC116 | RS1 | 0.642116 | 3 | 0 | 3 |
| CCDC116 | DNAH7 | 0.634418 | 3 | 0 | 3 |
| CCDC116 | LAMA5-AS1 | 0.63276 | 3 | 0 | 3 |
| CCDC116 | MIR4755 | 0.632712 | 5 | 0 | 5 |
| CCDC116 | LINC00293 | 0.632502 | 3 | 0 | 3 |
| CCDC116 | PITRM1-AS1 | 0.628733 | 3 | 0 | 3 |
For details and further investigation, click here
