| Full name: solute carrier family 4 member 1 (Diego blood group) | Alias Symbol: RTA1A|CD233|FR|SW|WR | ||
| Type: protein-coding gene | Cytoband: 17q21.31 | ||
| Entrez ID: 6521 | HGNC ID: HGNC:11027 | Ensembl Gene: ENSG00000004939 | OMIM ID: 109270 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC4A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC4A1 | 6521 | 205592_at | -0.0097 | 0.9772 | |
| GSE20347 | SLC4A1 | 6521 | 205592_at | 0.0795 | 0.4430 | |
| GSE23400 | SLC4A1 | 6521 | 205592_at | -0.0824 | 0.0128 | |
| GSE26886 | SLC4A1 | 6521 | 205592_at | -0.0517 | 0.8162 | |
| GSE29001 | SLC4A1 | 6521 | 205592_at | -0.0605 | 0.7599 | |
| GSE38129 | SLC4A1 | 6521 | 205592_at | -0.1548 | 0.1507 | |
| GSE45670 | SLC4A1 | 6521 | 205592_at | 0.0938 | 0.2164 | |
| GSE53622 | SLC4A1 | 6521 | 81861 | 0.3421 | 0.0000 | |
| GSE53624 | SLC4A1 | 6521 | 81861 | 0.0500 | 0.6425 | |
| GSE63941 | SLC4A1 | 6521 | 205592_at | 0.3545 | 0.0467 | |
| GSE77861 | SLC4A1 | 6521 | 205592_at | 0.0319 | 0.7265 | |
| GSE97050 | SLC4A1 | 6521 | A_33_P3400217 | 0.2449 | 0.2395 | |
| SRP133303 | SLC4A1 | 6521 | RNAseq | -0.0518 | 0.8249 | |
| SRP193095 | SLC4A1 | 6521 | RNAseq | -0.1589 | 0.3736 | |
| TCGA | SLC4A1 | 6521 | RNAseq | -1.6934 | 0.0792 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SLC4A1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC4A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC4A1 | 6521 | 5 | 2 | 23 | |
| GSE20123 | SLC4A1 | 6521 | 5 | 2 | 23 | |
| GSE43470 | SLC4A1 | 6521 | 1 | 2 | 40 | |
| GSE46452 | SLC4A1 | 6521 | 32 | 0 | 27 | |
| GSE47630 | SLC4A1 | 6521 | 9 | 0 | 31 | |
| GSE54993 | SLC4A1 | 6521 | 3 | 4 | 63 | |
| GSE54994 | SLC4A1 | 6521 | 8 | 5 | 40 | |
| GSE60625 | SLC4A1 | 6521 | 4 | 0 | 7 | |
| GSE74703 | SLC4A1 | 6521 | 1 | 1 | 34 | |
| GSE74704 | SLC4A1 | 6521 | 3 | 1 | 16 | |
| TCGA | SLC4A1 | 6521 | 23 | 7 | 66 |
Total number of gains: 94; Total number of losses: 24; Total Number of normals: 370.
Somatic mutations of SLC4A1:
Generating mutation plots.
Highly correlated genes for SLC4A1:
Showing top 20/1000 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC4A1 | CHMP6 | 0.765282 | 3 | 0 | 3 |
| SLC4A1 | GGT1 | 0.761394 | 3 | 0 | 3 |
| SLC4A1 | SNORA71A | 0.746767 | 3 | 0 | 3 |
| SLC4A1 | STRC | 0.738647 | 3 | 0 | 3 |
| SLC4A1 | GPR152 | 0.735833 | 3 | 0 | 3 |
| SLC4A1 | TMEM221 | 0.732293 | 3 | 0 | 3 |
| SLC4A1 | CRYAA | 0.728282 | 4 | 0 | 4 |
| SLC4A1 | CSH2 | 0.727154 | 3 | 0 | 3 |
| SLC4A1 | SCUBE1 | 0.720448 | 3 | 0 | 3 |
| SLC4A1 | KCTD19 | 0.714119 | 3 | 0 | 3 |
| SLC4A1 | DCD | 0.710037 | 4 | 0 | 3 |
| SLC4A1 | RNF17 | 0.708633 | 4 | 0 | 4 |
| SLC4A1 | PALM3 | 0.708477 | 4 | 0 | 4 |
| SLC4A1 | CHIT1 | 0.708184 | 3 | 0 | 3 |
| SLC4A1 | PRKAR1B | 0.70714 | 6 | 0 | 6 |
| SLC4A1 | PHOSPHO1 | 0.705658 | 4 | 0 | 4 |
| SLC4A1 | FFAR1 | 0.702506 | 4 | 0 | 4 |
| SLC4A1 | TMEM235 | 0.700527 | 4 | 0 | 4 |
| SLC4A1 | CD300LB | 0.699821 | 3 | 0 | 3 |
| SLC4A1 | MLXIPL | 0.697288 | 5 | 0 | 5 |
For details and further investigation, click here
