| Full name: killin, p53 regulated DNA replication inhibitor | Alias Symbol: killin | ||
| Type: protein-coding gene | Cytoband: 10q23 | ||
| Entrez ID: 100144748 | HGNC ID: HGNC:37212 | Ensembl Gene: ENSG00000227268 | OMIM ID: 612105 |
| Drug and gene relationship at DGIdb | |||
Expression of KLLN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KLLN | 100144748 | 244431_at | 0.0488 | 0.8664 | |
| GSE26886 | KLLN | 100144748 | 244431_at | -0.3448 | 0.0485 | |
| GSE45670 | KLLN | 100144748 | 244431_at | -0.0808 | 0.5550 | |
| GSE53622 | KLLN | 100144748 | 33766 | -0.2121 | 0.1506 | |
| GSE53624 | KLLN | 100144748 | 33766 | 0.0119 | 0.9375 | |
| GSE63941 | KLLN | 100144748 | 244431_at | 0.2406 | 0.0918 | |
| GSE77861 | KLLN | 100144748 | 244431_at | -0.1515 | 0.2843 | |
| SRP007169 | KLLN | 100144748 | RNAseq | -0.5816 | 0.3424 | |
| SRP064894 | KLLN | 100144748 | RNAseq | 0.4512 | 0.1107 | |
| SRP133303 | KLLN | 100144748 | RNAseq | 0.1985 | 0.1388 | |
| SRP159526 | KLLN | 100144748 | RNAseq | 0.8482 | 0.0281 | |
| SRP193095 | KLLN | 100144748 | RNAseq | 0.1323 | 0.3211 | |
| SRP219564 | KLLN | 100144748 | RNAseq | 0.3007 | 0.4387 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KLLN expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of KLLN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KLLN | 100144748 | 2 | 7 | 21 | |
| GSE20123 | KLLN | 100144748 | 2 | 6 | 22 | |
| GSE43470 | KLLN | 100144748 | 0 | 9 | 34 | |
| GSE46452 | KLLN | 100144748 | 0 | 11 | 48 | |
| GSE47630 | KLLN | 100144748 | 2 | 14 | 24 | |
| GSE54993 | KLLN | 100144748 | 7 | 0 | 63 | |
| GSE54994 | KLLN | 100144748 | 1 | 11 | 41 | |
| GSE60625 | KLLN | 100144748 | 0 | 0 | 11 | |
| GSE74703 | KLLN | 100144748 | 0 | 7 | 29 | |
| GSE74704 | KLLN | 100144748 | 1 | 4 | 15 | |
| TCGA | KLLN | 100144748 | 6 | 29 | 61 |
Total number of gains: 21; Total number of losses: 98; Total Number of normals: 369.
Somatic mutations of KLLN:
Generating mutation plots.
Highly correlated genes for KLLN:
Showing top 20/119 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KLLN | COL9A2 | 0.69334 | 3 | 0 | 3 |
| KLLN | SPRR4 | 0.692837 | 3 | 0 | 3 |
| KLLN | ADAD1 | 0.674238 | 4 | 0 | 4 |
| KLLN | SLC25A35 | 0.66604 | 3 | 0 | 3 |
| KLLN | NMUR2 | 0.660773 | 4 | 0 | 3 |
| KLLN | GPR21 | 0.654478 | 3 | 0 | 3 |
| KLLN | KLK4 | 0.651047 | 4 | 0 | 3 |
| KLLN | SCN10A | 0.64695 | 4 | 0 | 3 |
| KLLN | CD33 | 0.645472 | 3 | 0 | 3 |
| KLLN | ADARB2-AS1 | 0.633958 | 4 | 0 | 4 |
| KLLN | TNP2 | 0.629343 | 4 | 0 | 3 |
| KLLN | UBXN11 | 0.625917 | 3 | 0 | 3 |
| KLLN | CA1 | 0.625863 | 4 | 0 | 3 |
| KLLN | PRB1 | 0.623473 | 5 | 0 | 4 |
| KLLN | FMN1 | 0.623279 | 3 | 0 | 3 |
| KLLN | LINC01119 | 0.618675 | 4 | 0 | 3 |
| KLLN | CACNG4 | 0.618128 | 5 | 0 | 4 |
| KLLN | MORF4L2-AS1 | 0.61779 | 4 | 0 | 3 |
| KLLN | MMD2 | 0.614855 | 4 | 0 | 4 |
| KLLN | UNC79 | 0.614472 | 5 | 0 | 3 |
For details and further investigation, click here
