| Full name: afamin | Alias Symbol: ALB2|ALBA | ||
| Type: protein-coding gene | Cytoband: 4q13.3 | ||
| Entrez ID: 173 | HGNC ID: HGNC:316 | Ensembl Gene: ENSG00000079557 | OMIM ID: 104145 |
| Drug and gene relationship at DGIdb | |||
Expression of AFM:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AFM | 173 | 206840_at | -0.0237 | 0.9394 | |
| GSE20347 | AFM | 173 | 206840_at | -0.0162 | 0.7919 | |
| GSE23400 | AFM | 173 | 206840_at | -0.0599 | 0.0374 | |
| GSE26886 | AFM | 173 | 206840_at | 0.0711 | 0.2918 | |
| GSE29001 | AFM | 173 | 206840_at | -0.0566 | 0.7009 | |
| GSE38129 | AFM | 173 | 206840_at | -0.0291 | 0.6574 | |
| GSE45670 | AFM | 173 | 206840_at | 0.1690 | 0.0375 | |
| GSE53622 | AFM | 173 | 41321 | 0.1144 | 0.5575 | |
| GSE53624 | AFM | 173 | 2808 | 0.0823 | 0.5276 | |
| GSE63941 | AFM | 173 | 206840_at | -0.0403 | 0.7754 | |
| GSE77861 | AFM | 173 | 206840_at | 0.0600 | 0.5720 | |
| TCGA | AFM | 173 | RNAseq | -5.2699 | 0.0462 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by AFM expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AFM:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AFM | 173 | 2 | 9 | 19 | |
| GSE20123 | AFM | 173 | 2 | 9 | 19 | |
| GSE43470 | AFM | 173 | 0 | 13 | 30 | |
| GSE46452 | AFM | 173 | 3 | 34 | 22 | |
| GSE47630 | AFM | 173 | 1 | 19 | 20 | |
| GSE54993 | AFM | 173 | 7 | 0 | 63 | |
| GSE54994 | AFM | 173 | 1 | 9 | 43 | |
| GSE60625 | AFM | 173 | 0 | 0 | 11 | |
| GSE74703 | AFM | 173 | 0 | 11 | 25 | |
| GSE74704 | AFM | 173 | 2 | 5 | 13 | |
| TCGA | AFM | 173 | 19 | 27 | 50 |
Total number of gains: 37; Total number of losses: 136; Total Number of normals: 315.
Somatic mutations of AFM:
Generating mutation plots.
Highly correlated genes for AFM:
Showing top 20/101 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AFM | KHDRBS2 | 0.720377 | 3 | 0 | 3 |
| AFM | PSG9 | 0.680322 | 3 | 0 | 3 |
| AFM | ZNF460 | 0.661532 | 4 | 0 | 3 |
| AFM | TAS2R9 | 0.651075 | 4 | 0 | 3 |
| AFM | ARMC4 | 0.648177 | 3 | 0 | 3 |
| AFM | GUCY1A2 | 0.645077 | 3 | 0 | 3 |
| AFM | SYN1 | 0.643476 | 3 | 0 | 3 |
| AFM | SPTA1 | 0.626611 | 5 | 0 | 4 |
| AFM | CPA2 | 0.625075 | 4 | 0 | 3 |
| AFM | OR2J2 | 0.622127 | 3 | 0 | 3 |
| AFM | COLEC10 | 0.617029 | 3 | 0 | 3 |
| AFM | CNR2 | 0.616728 | 4 | 0 | 3 |
| AFM | MAGEA8 | 0.616035 | 3 | 0 | 3 |
| AFM | KCNE2 | 0.60926 | 3 | 0 | 3 |
| AFM | PTPRJ | 0.609003 | 4 | 0 | 3 |
| AFM | TAS2R16 | 0.607592 | 4 | 0 | 4 |
| AFM | RFX6 | 0.605824 | 3 | 0 | 3 |
| AFM | DDN | 0.600952 | 3 | 0 | 3 |
| AFM | RNF185-AS1 | 0.598467 | 4 | 0 | 4 |
| AFM | CISH | 0.59805 | 4 | 0 | 3 |
For details and further investigation, click here
