| Full name: dendrin | Alias Symbol: KIAA0749 | ||
| Type: protein-coding gene | Cytoband: 12q13.12 | ||
| Entrez ID: 23109 | HGNC ID: HGNC:24458 | Ensembl Gene: ENSG00000181418 | OMIM ID: 610588 |
| Drug and gene relationship at DGIdb | |||
Expression of DDN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DDN | 23109 | 214788_x_at | 0.1909 | 0.3639 | |
| GSE20347 | DDN | 23109 | 214788_x_at | 0.0533 | 0.5404 | |
| GSE23400 | DDN | 23109 | 214788_x_at | -0.0843 | 0.0488 | |
| GSE26886 | DDN | 23109 | 214788_x_at | 0.4079 | 0.0041 | |
| GSE29001 | DDN | 23109 | 214788_x_at | -0.0035 | 0.9841 | |
| GSE38129 | DDN | 23109 | 214788_x_at | 0.0898 | 0.2708 | |
| GSE45670 | DDN | 23109 | 214788_x_at | 0.2075 | 0.0587 | |
| GSE53622 | DDN | 23109 | 21234 | 1.2764 | 0.0000 | |
| GSE53624 | DDN | 23109 | 21234 | 1.6564 | 0.0000 | |
| GSE63941 | DDN | 23109 | 214788_x_at | 0.4273 | 0.0795 | |
| GSE77861 | DDN | 23109 | 214788_x_at | 0.0501 | 0.6962 | |
| GSE97050 | DDN | 23109 | A_23_P2317 | -0.2722 | 0.4062 | |
| SRP133303 | DDN | 23109 | RNAseq | 0.6897 | 0.0142 | |
| SRP159526 | DDN | 23109 | RNAseq | 1.7226 | 0.0047 | |
| TCGA | DDN | 23109 | RNAseq | 0.5522 | 0.0364 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by DDN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DDN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DDN | 23109 | 6 | 1 | 23 | |
| GSE20123 | DDN | 23109 | 6 | 1 | 23 | |
| GSE43470 | DDN | 23109 | 4 | 1 | 38 | |
| GSE46452 | DDN | 23109 | 8 | 1 | 50 | |
| GSE47630 | DDN | 23109 | 11 | 2 | 27 | |
| GSE54993 | DDN | 23109 | 0 | 5 | 65 | |
| GSE54994 | DDN | 23109 | 4 | 1 | 48 | |
| GSE60625 | DDN | 23109 | 0 | 0 | 11 | |
| GSE74703 | DDN | 23109 | 4 | 1 | 31 | |
| GSE74704 | DDN | 23109 | 4 | 1 | 15 | |
| TCGA | DDN | 23109 | 16 | 15 | 65 |
Total number of gains: 63; Total number of losses: 29; Total Number of normals: 396.
Somatic mutations of DDN:
Generating mutation plots.
Highly correlated genes for DDN:
Showing top 20/540 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DDN | FZR1 | 0.698911 | 3 | 0 | 3 |
| DDN | RILP | 0.69342 | 3 | 0 | 3 |
| DDN | GALNT8 | 0.682435 | 4 | 0 | 4 |
| DDN | PDE6B | 0.681286 | 3 | 0 | 3 |
| DDN | WDR62 | 0.655444 | 4 | 0 | 4 |
| DDN | FOXD2-AS1 | 0.654748 | 5 | 0 | 5 |
| DDN | KIF7 | 0.653119 | 3 | 0 | 3 |
| DDN | CHST8 | 0.650162 | 4 | 0 | 4 |
| DDN | ZNF593 | 0.648735 | 3 | 0 | 3 |
| DDN | IFNA1 | 0.637167 | 4 | 0 | 3 |
| DDN | OR10H3 | 0.635525 | 5 | 0 | 4 |
| DDN | DNAH11 | 0.634146 | 3 | 0 | 3 |
| DDN | FABP7 | 0.632895 | 4 | 0 | 3 |
| DDN | KLK14 | 0.631633 | 6 | 0 | 4 |
| DDN | PPP2R5B | 0.626521 | 6 | 0 | 5 |
| DDN | GLI3 | 0.626498 | 3 | 0 | 3 |
| DDN | KCNA4 | 0.626159 | 3 | 0 | 3 |
| DDN | CLDN18 | 0.622861 | 4 | 0 | 4 |
| DDN | NOXO1 | 0.61968 | 3 | 0 | 3 |
| DDN | PSG9 | 0.616989 | 5 | 0 | 4 |
For details and further investigation, click here
