| Full name: protein tyrosine phosphatase receptor type J | Alias Symbol: DEP1|HPTPeta|CD148 | ||
| Type: protein-coding gene | Cytoband: 11p11.2 | ||
| Entrez ID: 5795 | HGNC ID: HGNC:9673 | Ensembl Gene: ENSG00000149177 | OMIM ID: 600925 |
| Drug and gene relationship at DGIdb | |||
PTPRJ involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04520 | Adherens junction |
Expression of PTPRJ:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PTPRJ | 5795 | 227396_at | 0.5382 | 0.4457 | |
| GSE20347 | PTPRJ | 5795 | 214137_at | 0.0016 | 0.9874 | |
| GSE23400 | PTPRJ | 5795 | 214137_at | -0.1181 | 0.0001 | |
| GSE26886 | PTPRJ | 5795 | 227396_at | -0.3634 | 0.3609 | |
| GSE29001 | PTPRJ | 5795 | 214137_at | -0.0945 | 0.6245 | |
| GSE38129 | PTPRJ | 5795 | 214137_at | -0.0367 | 0.6376 | |
| GSE45670 | PTPRJ | 5795 | 227396_at | 0.3044 | 0.2446 | |
| GSE53622 | PTPRJ | 5795 | 125540 | 0.4322 | 0.0025 | |
| GSE53624 | PTPRJ | 5795 | 125540 | 0.4973 | 0.0096 | |
| GSE63941 | PTPRJ | 5795 | 227396_at | -1.5121 | 0.1179 | |
| GSE77861 | PTPRJ | 5795 | 227396_at | 0.4894 | 0.0423 | |
| GSE97050 | PTPRJ | 5795 | A_24_P921321 | 0.1271 | 0.5900 | |
| SRP007169 | PTPRJ | 5795 | RNAseq | 2.1821 | 0.0036 | |
| SRP008496 | PTPRJ | 5795 | RNAseq | 2.3783 | 0.0000 | |
| SRP064894 | PTPRJ | 5795 | RNAseq | 0.6148 | 0.0111 | |
| SRP133303 | PTPRJ | 5795 | RNAseq | 0.4929 | 0.0008 | |
| SRP159526 | PTPRJ | 5795 | RNAseq | 1.0840 | 0.0359 | |
| SRP193095 | PTPRJ | 5795 | RNAseq | 0.3419 | 0.1862 | |
| SRP219564 | PTPRJ | 5795 | RNAseq | 0.9521 | 0.0096 | |
| TCGA | PTPRJ | 5795 | RNAseq | -0.5603 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by PTPRJ expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PTPRJ:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PTPRJ | 5795 | 3 | 8 | 19 | |
| GSE20123 | PTPRJ | 5795 | 3 | 7 | 20 | |
| GSE43470 | PTPRJ | 5795 | 1 | 4 | 38 | |
| GSE46452 | PTPRJ | 5795 | 9 | 5 | 45 | |
| GSE47630 | PTPRJ | 5795 | 3 | 9 | 28 | |
| GSE54993 | PTPRJ | 5795 | 3 | 0 | 67 | |
| GSE54994 | PTPRJ | 5795 | 1 | 11 | 41 | |
| GSE60625 | PTPRJ | 5795 | 0 | 0 | 11 | |
| GSE74703 | PTPRJ | 5795 | 1 | 2 | 33 | |
| GSE74704 | PTPRJ | 5795 | 2 | 5 | 13 | |
| TCGA | PTPRJ | 5795 | 11 | 20 | 65 |
Total number of gains: 37; Total number of losses: 71; Total Number of normals: 380.
Somatic mutations of PTPRJ:
Generating mutation plots.
Highly correlated genes for PTPRJ:
Showing top 20/557 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PTPRJ | GLE1 | 0.809701 | 3 | 0 | 3 |
| PTPRJ | RAB11FIP5 | 0.754574 | 3 | 0 | 3 |
| PTPRJ | ODF1 | 0.742243 | 4 | 0 | 4 |
| PTPRJ | ZNF18 | 0.732739 | 3 | 0 | 3 |
| PTPRJ | EXOC8 | 0.722181 | 3 | 0 | 3 |
| PTPRJ | KCNV1 | 0.719778 | 3 | 0 | 3 |
| PTPRJ | LALBA | 0.716583 | 4 | 0 | 4 |
| PTPRJ | TCL1B | 0.713173 | 5 | 0 | 5 |
| PTPRJ | TAF1 | 0.712525 | 3 | 0 | 3 |
| PTPRJ | POU4F2 | 0.711781 | 3 | 0 | 3 |
| PTPRJ | HPS3 | 0.711212 | 4 | 0 | 3 |
| PTPRJ | GP1BA | 0.707199 | 4 | 0 | 4 |
| PTPRJ | TLR2 | 0.705549 | 5 | 0 | 5 |
| PTPRJ | FZR1 | 0.704861 | 3 | 0 | 3 |
| PTPRJ | SCN11A | 0.702446 | 4 | 0 | 4 |
| PTPRJ | SIDT2 | 0.701985 | 4 | 0 | 4 |
| PTPRJ | FPR3 | 0.70083 | 6 | 0 | 6 |
| PTPRJ | ITGAM | 0.698881 | 5 | 0 | 4 |
| PTPRJ | CERKL | 0.698324 | 3 | 0 | 3 |
| PTPRJ | PRLR | 0.698123 | 5 | 0 | 5 |
For details and further investigation, click here
