| Full name: regulatory factor X6 | Alias Symbol: MGC33442|dJ955L16.1 | ||
| Type: protein-coding gene | Cytoband: 6q22.1 | ||
| Entrez ID: 222546 | HGNC ID: HGNC:21478 | Ensembl Gene: ENSG00000185002 | OMIM ID: 612659 |
| Drug and gene relationship at DGIdb | |||
Expression of RFX6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RFX6 | 222546 | 1552673_at | 0.0221 | 0.9455 | |
| GSE26886 | RFX6 | 222546 | 1552673_at | 0.2198 | 0.1821 | |
| GSE45670 | RFX6 | 222546 | 1552673_at | 0.1116 | 0.1449 | |
| GSE53622 | RFX6 | 222546 | 46541 | -0.1840 | 0.4428 | |
| GSE53624 | RFX6 | 222546 | 46541 | -0.3374 | 0.0364 | |
| GSE63941 | RFX6 | 222546 | 1552673_at | 0.1925 | 0.7866 | |
| GSE77861 | RFX6 | 222546 | 1552673_at | 0.0231 | 0.7970 | |
| TCGA | RFX6 | 222546 | RNAseq | -5.3197 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by RFX6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RFX6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RFX6 | 222546 | 1 | 4 | 25 | |
| GSE20123 | RFX6 | 222546 | 1 | 3 | 26 | |
| GSE43470 | RFX6 | 222546 | 3 | 1 | 39 | |
| GSE46452 | RFX6 | 222546 | 2 | 11 | 46 | |
| GSE47630 | RFX6 | 222546 | 9 | 4 | 27 | |
| GSE54993 | RFX6 | 222546 | 3 | 2 | 65 | |
| GSE54994 | RFX6 | 222546 | 8 | 8 | 37 | |
| GSE60625 | RFX6 | 222546 | 0 | 1 | 10 | |
| GSE74703 | RFX6 | 222546 | 2 | 1 | 33 | |
| GSE74704 | RFX6 | 222546 | 0 | 1 | 19 | |
| TCGA | RFX6 | 222546 | 7 | 22 | 67 |
Total number of gains: 36; Total number of losses: 58; Total Number of normals: 394.
Somatic mutations of RFX6:
Generating mutation plots.
Highly correlated genes for RFX6:
Showing all 16 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RFX6 | REG3G | 0.695632 | 3 | 0 | 3 |
| RFX6 | TTR | 0.683456 | 3 | 0 | 3 |
| RFX6 | SYT4 | 0.668831 | 3 | 0 | 3 |
| RFX6 | TREM1 | 0.666068 | 3 | 0 | 3 |
| RFX6 | ETNPPL | 0.65495 | 4 | 0 | 3 |
| RFX6 | RASD2 | 0.630351 | 3 | 0 | 3 |
| RFX6 | AFM | 0.605824 | 3 | 0 | 3 |
| RFX6 | SNAP91 | 0.598502 | 4 | 0 | 3 |
| RFX6 | ATP4B | 0.571747 | 3 | 0 | 3 |
| RFX6 | TES | 0.565329 | 3 | 0 | 3 |
| RFX6 | FAM186A | 0.557696 | 4 | 0 | 3 |
| RFX6 | MUC19 | 0.556883 | 4 | 0 | 3 |
| RFX6 | RGCC | 0.555258 | 3 | 0 | 3 |
| RFX6 | ESRRG | 0.544209 | 5 | 0 | 3 |
| RFX6 | LINC01146 | 0.538421 | 3 | 0 | 3 |
| RFX6 | SMIM6 | 0.535486 | 4 | 0 | 3 |
For details and further investigation, click here
