| Full name: agouti related neuropeptide | Alias Symbol: Agrt|ART|ASIP2 | ||
| Type: protein-coding gene | Cytoband: 16q22.1 | ||
| Entrez ID: 181 | HGNC ID: HGNC:330 | Ensembl Gene: ENSG00000159723 | OMIM ID: 602311 |
| Drug and gene relationship at DGIdb | |||
AGRP involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04920 | Adipocytokine signaling pathway |
Expression of AGRP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AGRP | 181 | 207193_at | -0.0859 | 0.7558 | |
| GSE20347 | AGRP | 181 | 207193_at | -0.0012 | 0.9912 | |
| GSE23400 | AGRP | 181 | 207193_at | -0.1852 | 0.0000 | |
| GSE26886 | AGRP | 181 | 207193_at | 0.2575 | 0.0110 | |
| GSE29001 | AGRP | 181 | 207193_at | 0.0430 | 0.8251 | |
| GSE38129 | AGRP | 181 | 207193_at | -0.1052 | 0.0923 | |
| GSE45670 | AGRP | 181 | 207193_at | 0.2040 | 0.0043 | |
| GSE53622 | AGRP | 181 | 13177 | 0.1552 | 0.0633 | |
| GSE53624 | AGRP | 181 | 13177 | 0.1570 | 0.0659 | |
| GSE63941 | AGRP | 181 | 207193_at | -0.0739 | 0.5860 | |
| GSE77861 | AGRP | 181 | 207193_at | -0.1016 | 0.3309 | |
| GSE97050 | AGRP | 181 | A_33_P3279470 | 0.1627 | 0.4079 | |
| TCGA | AGRP | 181 | RNAseq | -0.5725 | 0.4574 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by AGRP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AGRP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AGRP | 181 | 9 | 2 | 19 | |
| GSE20123 | AGRP | 181 | 9 | 2 | 19 | |
| GSE43470 | AGRP | 181 | 1 | 9 | 33 | |
| GSE46452 | AGRP | 181 | 38 | 1 | 20 | |
| GSE47630 | AGRP | 181 | 10 | 8 | 22 | |
| GSE54993 | AGRP | 181 | 2 | 4 | 64 | |
| GSE54994 | AGRP | 181 | 8 | 10 | 35 | |
| GSE60625 | AGRP | 181 | 4 | 0 | 7 | |
| GSE74703 | AGRP | 181 | 1 | 6 | 29 | |
| GSE74704 | AGRP | 181 | 5 | 1 | 14 | |
| TCGA | AGRP | 181 | 29 | 12 | 55 |
Total number of gains: 116; Total number of losses: 55; Total Number of normals: 317.
Somatic mutations of AGRP:
Generating mutation plots.
Highly correlated genes for AGRP:
Showing top 20/1104 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AGRP | STRC | 0.866903 | 3 | 0 | 3 |
| AGRP | DCDC1 | 0.83345 | 3 | 0 | 3 |
| AGRP | CD72 | 0.828607 | 3 | 0 | 3 |
| AGRP | ZNF527 | 0.816583 | 3 | 0 | 3 |
| AGRP | YY2 | 0.8023 | 3 | 0 | 3 |
| AGRP | LHB | 0.802226 | 3 | 0 | 3 |
| AGRP | PLA2G2C | 0.800538 | 3 | 0 | 3 |
| AGRP | PRSS38 | 0.78787 | 3 | 0 | 3 |
| AGRP | C9orf153 | 0.786377 | 3 | 0 | 3 |
| AGRP | CHMP6 | 0.781772 | 3 | 0 | 3 |
| AGRP | C1QL2 | 0.780262 | 3 | 0 | 3 |
| AGRP | BAHCC1 | 0.779434 | 3 | 0 | 3 |
| AGRP | IL1F10 | 0.775442 | 3 | 0 | 3 |
| AGRP | SLC9A7 | 0.771296 | 3 | 0 | 3 |
| AGRP | SLC22A31 | 0.77084 | 4 | 0 | 4 |
| AGRP | OR2A5 | 0.767072 | 3 | 0 | 3 |
| AGRP | BSX | 0.76512 | 3 | 0 | 3 |
| AGRP | OR2T27 | 0.76299 | 3 | 0 | 3 |
| AGRP | PABPN1L | 0.761874 | 3 | 0 | 3 |
| AGRP | OR2T1 | 0.760829 | 3 | 0 | 3 |
For details and further investigation, click here
