| Full name: serine protease 38 | Alias Symbol: MPN2 | ||
| Type: protein-coding gene | Cytoband: 1q42.13 | ||
| Entrez ID: 339501 | HGNC ID: HGNC:29625 | Ensembl Gene: ENSG00000185888 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of PRSS38:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | PRSS38 | 339501 | 126376 | 0.0151 | 0.8741 | |
| GSE53624 | PRSS38 | 339501 | 126376 | -0.0740 | 0.4458 | |
| GSE97050 | PRSS38 | 339501 | A_33_P3332166 | -0.0705 | 0.7984 | |
| TCGA | PRSS38 | 339501 | RNAseq | 1.0949 | 0.5061 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PRSS38 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRSS38:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRSS38 | 339501 | 11 | 0 | 19 | |
| GSE20123 | PRSS38 | 339501 | 11 | 0 | 19 | |
| GSE43470 | PRSS38 | 339501 | 7 | 1 | 35 | |
| GSE46452 | PRSS38 | 339501 | 3 | 1 | 55 | |
| GSE47630 | PRSS38 | 339501 | 15 | 0 | 25 | |
| GSE54993 | PRSS38 | 339501 | 0 | 6 | 64 | |
| GSE54994 | PRSS38 | 339501 | 17 | 0 | 36 | |
| GSE60625 | PRSS38 | 339501 | 0 | 0 | 11 | |
| GSE74703 | PRSS38 | 339501 | 7 | 1 | 28 | |
| GSE74704 | PRSS38 | 339501 | 5 | 0 | 15 | |
| TCGA | PRSS38 | 339501 | 45 | 2 | 49 |
Total number of gains: 121; Total number of losses: 11; Total Number of normals: 356.
Somatic mutations of PRSS38:
Generating mutation plots.
Highly correlated genes for PRSS38:
Showing top 20/285 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRSS38 | TXNDC2 | 0.889715 | 3 | 0 | 3 |
| PRSS38 | TRPM8 | 0.882762 | 3 | 0 | 3 |
| PRSS38 | YY2 | 0.881715 | 3 | 0 | 3 |
| PRSS38 | RBM43 | 0.870875 | 3 | 0 | 3 |
| PRSS38 | TTLL9 | 0.866581 | 3 | 0 | 3 |
| PRSS38 | FFAR1 | 0.864572 | 3 | 0 | 3 |
| PRSS38 | OR2B11 | 0.858573 | 3 | 0 | 3 |
| PRSS38 | GJD4 | 0.852166 | 3 | 0 | 3 |
| PRSS38 | CLEC1B | 0.849796 | 3 | 0 | 3 |
| PRSS38 | INSC | 0.848624 | 3 | 0 | 3 |
| PRSS38 | CPLX2 | 0.847634 | 3 | 0 | 3 |
| PRSS38 | SPRED3 | 0.846888 | 3 | 0 | 3 |
| PRSS38 | OR1F1 | 0.845531 | 3 | 0 | 3 |
| PRSS38 | RNF180 | 0.842895 | 3 | 0 | 3 |
| PRSS38 | TFE3 | 0.841541 | 3 | 0 | 3 |
| PRSS38 | KCNJ13 | 0.840969 | 3 | 0 | 3 |
| PRSS38 | PAX6 | 0.840429 | 3 | 0 | 3 |
| PRSS38 | C1QL2 | 0.84014 | 3 | 0 | 3 |
| PRSS38 | SLC22A12 | 0.840052 | 3 | 0 | 3 |
| PRSS38 | KCNQ4 | 0.838901 | 3 | 0 | 3 |
For details and further investigation, click here
