| Full name: CD72 molecule | Alias Symbol: LYB2|CD72b | ||
| Type: protein-coding gene | Cytoband: 9p13.3 | ||
| Entrez ID: 971 | HGNC ID: HGNC:1696 | Ensembl Gene: ENSG00000137101 | OMIM ID: 107272 |
| Drug and gene relationship at DGIdb | |||
CD72 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04662 | B cell receptor signaling pathway |
Expression of CD72:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CD72 | 971 | 215925_s_at | 0.4567 | 0.6244 | |
| GSE20347 | CD72 | 971 | 215925_s_at | 0.0096 | 0.9095 | |
| GSE23400 | CD72 | 971 | 215925_s_at | 0.0022 | 0.9513 | |
| GSE26886 | CD72 | 971 | 215925_s_at | 0.0530 | 0.6339 | |
| GSE29001 | CD72 | 971 | 215925_s_at | 0.2357 | 0.2388 | |
| GSE38129 | CD72 | 971 | 215925_s_at | -0.0161 | 0.9413 | |
| GSE45670 | CD72 | 971 | 215925_s_at | 0.1537 | 0.5849 | |
| GSE53622 | CD72 | 971 | 75052 | 0.0314 | 0.6318 | |
| GSE53624 | CD72 | 971 | 75052 | -0.0007 | 0.9943 | |
| GSE63941 | CD72 | 971 | 215925_s_at | -0.5818 | 0.0001 | |
| GSE77861 | CD72 | 971 | 215925_s_at | -0.0679 | 0.6421 | |
| GSE97050 | CD72 | 971 | A_33_P3417222 | 0.4299 | 0.1491 | |
| SRP064894 | CD72 | 971 | RNAseq | 2.1769 | 0.0000 | |
| SRP133303 | CD72 | 971 | RNAseq | 0.2915 | 0.3995 | |
| SRP159526 | CD72 | 971 | RNAseq | -0.5980 | 0.3732 | |
| SRP219564 | CD72 | 971 | RNAseq | 1.3127 | 0.0269 | |
| TCGA | CD72 | 971 | RNAseq | 0.2182 | 0.3595 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by CD72 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CD72:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CD72 | 971 | 3 | 12 | 15 | |
| GSE20123 | CD72 | 971 | 3 | 12 | 15 | |
| GSE43470 | CD72 | 971 | 3 | 10 | 30 | |
| GSE46452 | CD72 | 971 | 6 | 15 | 38 | |
| GSE47630 | CD72 | 971 | 1 | 20 | 19 | |
| GSE54993 | CD72 | 971 | 6 | 0 | 64 | |
| GSE54994 | CD72 | 971 | 6 | 12 | 35 | |
| GSE60625 | CD72 | 971 | 0 | 0 | 11 | |
| GSE74703 | CD72 | 971 | 2 | 7 | 27 | |
| GSE74704 | CD72 | 971 | 0 | 10 | 10 | |
| TCGA | CD72 | 971 | 17 | 44 | 35 |
Total number of gains: 47; Total number of losses: 142; Total Number of normals: 299.
Somatic mutations of CD72:
Generating mutation plots.
Highly correlated genes for CD72:
Showing top 20/323 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CD72 | FBRSL1 | 0.839931 | 3 | 0 | 3 |
| CD72 | STRC | 0.838 | 3 | 0 | 3 |
| CD72 | C10orf91 | 0.8378 | 3 | 0 | 3 |
| CD72 | AGRP | 0.828607 | 3 | 0 | 3 |
| CD72 | GRIK4 | 0.818121 | 3 | 0 | 3 |
| CD72 | KCTD19 | 0.800307 | 3 | 0 | 3 |
| CD72 | CLTCL1 | 0.797767 | 3 | 0 | 3 |
| CD72 | YY2 | 0.797151 | 3 | 0 | 3 |
| CD72 | SLC22A31 | 0.794081 | 4 | 0 | 4 |
| CD72 | SLC6A3 | 0.792746 | 3 | 0 | 3 |
| CD72 | DCDC1 | 0.788536 | 3 | 0 | 3 |
| CD72 | GPR152 | 0.780727 | 3 | 0 | 3 |
| CD72 | RNF180 | 0.778541 | 3 | 0 | 3 |
| CD72 | C9orf153 | 0.777512 | 3 | 0 | 3 |
| CD72 | FOXE3 | 0.775441 | 3 | 0 | 3 |
| CD72 | CPLX2 | 0.773473 | 3 | 0 | 3 |
| CD72 | MIRLET7BHG | 0.772 | 3 | 0 | 3 |
| CD72 | NPPB | 0.771936 | 3 | 0 | 3 |
| CD72 | SLC22A7 | 0.771899 | 3 | 0 | 3 |
| CD72 | C1QL2 | 0.76395 | 3 | 0 | 3 |
For details and further investigation, click here
