| Full name: olfactory receptor family 2 subfamily A member 5 | Alias Symbol: OR7-138|OR7-141 | ||
| Type: protein-coding gene | Cytoband: 7q35 | ||
| Entrez ID: 393046 | HGNC ID: HGNC:8232 | Ensembl Gene: ENSG00000221836 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
OR2A5 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04740 | Olfactory transduction |
Expression of OR2A5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | OR2A5 | 393046 | 62772 | 0.2604 | 0.0001 | |
| GSE53624 | OR2A5 | 393046 | 62772 | 0.3722 | 0.0002 | |
| GSE97050 | OR2A5 | 393046 | A_33_P3379680 | -0.1861 | 0.3452 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by OR2A5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OR2A5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OR2A5 | 393046 | 3 | 2 | 25 | |
| GSE20123 | OR2A5 | 393046 | 3 | 2 | 25 | |
| GSE43470 | OR2A5 | 393046 | 3 | 4 | 36 | |
| GSE46452 | OR2A5 | 393046 | 7 | 2 | 50 | |
| GSE47630 | OR2A5 | 393046 | 6 | 8 | 26 | |
| GSE54993 | OR2A5 | 393046 | 3 | 4 | 63 | |
| GSE54994 | OR2A5 | 393046 | 5 | 8 | 40 | |
| GSE60625 | OR2A5 | 393046 | 0 | 0 | 11 | |
| GSE74703 | OR2A5 | 393046 | 2 | 4 | 30 | |
| GSE74704 | OR2A5 | 393046 | 1 | 2 | 17 | |
| TCGA | OR2A5 | 393046 | 28 | 26 | 42 |
Total number of gains: 61; Total number of losses: 62; Total Number of normals: 365.
Somatic mutations of OR2A5:
Generating mutation plots.
Highly correlated genes for OR2A5:
Showing top 20/284 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OR2A5 | DEFB121 | 0.869307 | 3 | 0 | 3 |
| OR2A5 | CIB3 | 0.867355 | 3 | 0 | 3 |
| OR2A5 | SERPINA10 | 0.845712 | 3 | 0 | 3 |
| OR2A5 | OR2T1 | 0.832745 | 3 | 0 | 3 |
| OR2A5 | TMEM105 | 0.831981 | 3 | 0 | 3 |
| OR2A5 | GCM2 | 0.828942 | 3 | 0 | 3 |
| OR2A5 | TTLL9 | 0.827529 | 3 | 0 | 3 |
| OR2A5 | SLC26A1 | 0.826567 | 3 | 0 | 3 |
| OR2A5 | ST8SIA3 | 0.824704 | 3 | 0 | 3 |
| OR2A5 | PLA2G2D | 0.822948 | 3 | 0 | 3 |
| OR2A5 | DCDC1 | 0.821816 | 3 | 0 | 3 |
| OR2A5 | SIM1 | 0.819854 | 3 | 0 | 3 |
| OR2A5 | SLC22A25 | 0.818374 | 3 | 0 | 3 |
| OR2A5 | ZNF236 | 0.816731 | 3 | 0 | 3 |
| OR2A5 | KCNH3 | 0.816091 | 3 | 0 | 3 |
| OR2A5 | WDR87 | 0.814991 | 3 | 0 | 3 |
| OR2A5 | CLTCL1 | 0.81436 | 3 | 0 | 3 |
| OR2A5 | FOXE3 | 0.81237 | 3 | 0 | 3 |
| OR2A5 | GPR182 | 0.81121 | 3 | 0 | 3 |
| OR2A5 | GYPE | 0.811072 | 3 | 0 | 3 |
For details and further investigation, click here
