OR2T1

 

Full name: olfactory receptor family 2 subfamily T member 1 Alias Symbol: OR1-25
Type: protein-coding gene Cytoband: 1q44
Entrez ID: 26696 HGNC ID: HGNC:8277 Ensembl Gene: ENSG00000175143 OMIM ID: 
Drug and gene relationship at DGIdb

 

OR2T1 involved pathways:

KEGG pathway Description View
hsa04740Olfactory transduction

 

Expression of OR2T1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 OR2T1 26696 21825 0.1942 0.0007
GSE53624 OR2T1 26696 21825 0.1423 0.0793
GSE97050 OR2T1 26696 A_33_P3246523 -0.0900 0.6585

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by OR2T1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of OR2T1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 OR2T1 26696 8 1 21
GSE20123 OR2T1 26696 7 1 22
GSE43470 OR2T1 26696 4 3 36
GSE46452 OR2T1 26696 4 2 53
GSE47630 OR2T1 26696 15 1 24
GSE54993 OR2T1 26696 0 6 64
GSE54994 OR2T1 26696 18 0 35
GSE60625 OR2T1 26696 0 0 11
GSE74703 OR2T1 26696 4 1 31
GSE74704 OR2T1 26696 2 0 18
TCGA OR2T1 26696 45 4 47

Total number of gains: 107; Total number of losses: 19; Total Number of normals: 362.  


 

Somatic mutations of OR2T1:

 

Generating mutation plots.

 

Highly correlated genes for OR2T1:

 

Showing top 20/298 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
OR2T1INSC0.862612303
OR2T1PNMA30.861655303
OR2T1KCNQ40.852517303
OR2T1DEFB1210.849932303
OR2T1CIB30.844026303
OR2T1FFAR10.839744303
OR2T1RASL10B0.838497303
OR2T1OR2A50.832745303
OR2T1ST8SIA10.832435303
OR2T1CLDN90.832069303
OR2T1SLC26A10.831082303
OR2T1ZNF2360.830948303
OR2T1SERPINA100.829497303
OR2T1SIM10.827411303
OR2T1GPR1820.826541303
OR2T1PLA2G2D0.824964303
OR2T1TXNDC20.823056303
OR2T1DCDC10.822257303
OR2T1AANAT0.820547303
OR2T1CHST100.819951303

For details and further investigation, click here