| Full name: aspartate beta-hydroxylase domain containing 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 16p11.2 | ||
| Entrez ID: 253982 | HGNC ID: HGNC:27380 | Ensembl Gene: ENSG00000174939 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ASPHD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ASPHD1 | 253982 | 1553997_a_at | 0.5712 | 0.1652 | |
| GSE20347 | ASPHD1 | 253982 | 214993_at | 0.1780 | 0.0363 | |
| GSE23400 | ASPHD1 | 253982 | 214993_at | -0.0248 | 0.5418 | |
| GSE26886 | ASPHD1 | 253982 | 214993_at | 0.8181 | 0.0001 | |
| GSE29001 | ASPHD1 | 253982 | 214993_at | 0.2419 | 0.0319 | |
| GSE38129 | ASPHD1 | 253982 | 214993_at | 0.3452 | 0.0012 | |
| GSE45670 | ASPHD1 | 253982 | 1553997_a_at | 0.4482 | 0.0170 | |
| GSE53622 | ASPHD1 | 253982 | 93520 | 0.4467 | 0.0000 | |
| GSE53624 | ASPHD1 | 253982 | 93520 | 0.7445 | 0.0000 | |
| GSE63941 | ASPHD1 | 253982 | 1553997_a_at | -0.4114 | 0.6125 | |
| GSE77861 | ASPHD1 | 253982 | 1553997_a_at | -0.0024 | 0.9823 | |
| GSE97050 | ASPHD1 | 253982 | A_33_P3314276 | 0.1938 | 0.5316 | |
| SRP064894 | ASPHD1 | 253982 | RNAseq | 2.6919 | 0.0000 | |
| SRP133303 | ASPHD1 | 253982 | RNAseq | 1.7796 | 0.0000 | |
| SRP219564 | ASPHD1 | 253982 | RNAseq | 3.3922 | 0.0000 | |
| TCGA | ASPHD1 | 253982 | RNAseq | -0.8878 | 0.0016 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by ASPHD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ASPHD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ASPHD1 | 253982 | 5 | 5 | 20 | |
| GSE20123 | ASPHD1 | 253982 | 5 | 4 | 21 | |
| GSE43470 | ASPHD1 | 253982 | 3 | 3 | 37 | |
| GSE46452 | ASPHD1 | 253982 | 38 | 1 | 20 | |
| GSE47630 | ASPHD1 | 253982 | 11 | 7 | 22 | |
| GSE54993 | ASPHD1 | 253982 | 3 | 5 | 62 | |
| GSE54994 | ASPHD1 | 253982 | 5 | 9 | 39 | |
| GSE60625 | ASPHD1 | 253982 | 4 | 0 | 7 | |
| GSE74703 | ASPHD1 | 253982 | 3 | 2 | 31 | |
| GSE74704 | ASPHD1 | 253982 | 3 | 2 | 15 | |
| TCGA | ASPHD1 | 253982 | 20 | 11 | 65 |
Total number of gains: 100; Total number of losses: 49; Total Number of normals: 339.
Somatic mutations of ASPHD1:
Generating mutation plots.
Highly correlated genes for ASPHD1:
Showing top 20/443 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ASPHD1 | GPR150 | 0.851094 | 3 | 0 | 3 |
| ASPHD1 | MEGF10 | 0.769792 | 3 | 0 | 3 |
| ASPHD1 | AIRE | 0.763273 | 3 | 0 | 3 |
| ASPHD1 | NAT8B | 0.747614 | 3 | 0 | 3 |
| ASPHD1 | SPATA45 | 0.745218 | 3 | 0 | 3 |
| ASPHD1 | BCL6B | 0.74437 | 3 | 0 | 3 |
| ASPHD1 | TEKT2 | 0.737968 | 3 | 0 | 3 |
| ASPHD1 | NPW | 0.733305 | 4 | 0 | 4 |
| ASPHD1 | EMID1 | 0.732548 | 3 | 0 | 3 |
| ASPHD1 | MAG | 0.725451 | 3 | 0 | 3 |
| ASPHD1 | NID2 | 0.714435 | 4 | 0 | 3 |
| ASPHD1 | CACNA1I | 0.712498 | 3 | 0 | 3 |
| ASPHD1 | OR7A17 | 0.710083 | 5 | 0 | 4 |
| ASPHD1 | CDHR5 | 0.708057 | 3 | 0 | 3 |
| ASPHD1 | ARL9 | 0.705829 | 3 | 0 | 3 |
| ASPHD1 | ZNF697 | 0.705192 | 4 | 0 | 3 |
| ASPHD1 | WDR90 | 0.701967 | 4 | 0 | 4 |
| ASPHD1 | ZNF777 | 0.698071 | 3 | 0 | 3 |
| ASPHD1 | OR56A5 | 0.690127 | 3 | 0 | 3 |
| ASPHD1 | MS4A18 | 0.683655 | 3 | 0 | 3 |
For details and further investigation, click here
