| Full name: tektin 2 | Alias Symbol: TEKTB1 | ||
| Type: protein-coding gene | Cytoband: 1p34.3 | ||
| Entrez ID: 27285 | HGNC ID: HGNC:11725 | Ensembl Gene: ENSG00000092850 | OMIM ID: 608953 |
| Drug and gene relationship at DGIdb | |||
Expression of TEKT2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TEKT2 | 27285 | 210323_at | -0.0295 | 0.9348 | |
| GSE20347 | TEKT2 | 27285 | 210323_at | -0.0401 | 0.6258 | |
| GSE23400 | TEKT2 | 27285 | 210323_at | -0.1476 | 0.0000 | |
| GSE26886 | TEKT2 | 27285 | 210323_at | 0.1811 | 0.2190 | |
| GSE29001 | TEKT2 | 27285 | 210323_at | -0.0603 | 0.5485 | |
| GSE38129 | TEKT2 | 27285 | 210323_at | -0.0526 | 0.5295 | |
| GSE45670 | TEKT2 | 27285 | 210323_at | 0.0279 | 0.7771 | |
| GSE53622 | TEKT2 | 27285 | 69220 | 0.0275 | 0.7515 | |
| GSE53624 | TEKT2 | 27285 | 69220 | 0.0758 | 0.4246 | |
| GSE63941 | TEKT2 | 27285 | 210323_at | 0.0237 | 0.9072 | |
| GSE77861 | TEKT2 | 27285 | 210323_at | -0.0554 | 0.6910 | |
| GSE97050 | TEKT2 | 27285 | A_23_P45955 | 0.0023 | 0.9924 | |
| SRP159526 | TEKT2 | 27285 | RNAseq | 1.3717 | 0.0881 | |
| TCGA | TEKT2 | 27285 | RNAseq | 0.7878 | 0.3050 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TEKT2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TEKT2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TEKT2 | 27285 | 3 | 5 | 22 | |
| GSE20123 | TEKT2 | 27285 | 2 | 4 | 24 | |
| GSE43470 | TEKT2 | 27285 | 7 | 2 | 34 | |
| GSE46452 | TEKT2 | 27285 | 4 | 1 | 54 | |
| GSE47630 | TEKT2 | 27285 | 8 | 3 | 29 | |
| GSE54993 | TEKT2 | 27285 | 1 | 1 | 68 | |
| GSE54994 | TEKT2 | 27285 | 11 | 2 | 40 | |
| GSE60625 | TEKT2 | 27285 | 0 | 0 | 11 | |
| GSE74703 | TEKT2 | 27285 | 6 | 1 | 29 | |
| GSE74704 | TEKT2 | 27285 | 1 | 0 | 19 | |
| TCGA | TEKT2 | 27285 | 11 | 19 | 66 |
Total number of gains: 54; Total number of losses: 38; Total Number of normals: 396.
Somatic mutations of TEKT2:
Generating mutation plots.
Highly correlated genes for TEKT2:
Showing top 20/388 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TEKT2 | C10orf91 | 0.798306 | 3 | 0 | 3 |
| TEKT2 | NPBWR1 | 0.758965 | 3 | 0 | 3 |
| TEKT2 | PALM3 | 0.752281 | 3 | 0 | 3 |
| TEKT2 | PPM1J | 0.752264 | 3 | 0 | 3 |
| TEKT2 | ATP2B3 | 0.746641 | 5 | 0 | 5 |
| TEKT2 | GH1 | 0.739447 | 3 | 0 | 3 |
| TEKT2 | CYP11B1 | 0.738702 | 4 | 0 | 4 |
| TEKT2 | ASPHD1 | 0.737968 | 3 | 0 | 3 |
| TEKT2 | SLC22A12 | 0.721827 | 3 | 0 | 3 |
| TEKT2 | TNFSF11 | 0.715126 | 4 | 0 | 3 |
| TEKT2 | OBSL1 | 0.7149 | 4 | 0 | 4 |
| TEKT2 | LELP1 | 0.713371 | 3 | 0 | 3 |
| TEKT2 | HTR1A | 0.707834 | 3 | 0 | 3 |
| TEKT2 | DAO | 0.699997 | 4 | 0 | 4 |
| TEKT2 | DOK7 | 0.69969 | 3 | 0 | 3 |
| TEKT2 | GPHB5 | 0.698748 | 3 | 0 | 3 |
| TEKT2 | ANKFN1 | 0.698339 | 3 | 0 | 3 |
| TEKT2 | CDH22 | 0.697372 | 3 | 0 | 3 |
| TEKT2 | SEC14L4 | 0.692276 | 3 | 0 | 3 |
| TEKT2 | KCNJ11 | 0.690855 | 3 | 0 | 3 |
For details and further investigation, click here
