| Full name: neuropeptide W | Alias Symbol: PPL8 | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 283869 | HGNC ID: HGNC:30509 | Ensembl Gene: ENSG00000183971 | OMIM ID: 607997 |
| Drug and gene relationship at DGIdb | |||
Expression of NPW:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NPW | 283869 | 243110_x_at | 1.8206 | 0.1613 | |
| GSE26886 | NPW | 283869 | 243110_x_at | 0.7630 | 0.0000 | |
| GSE45670 | NPW | 283869 | 243110_x_at | 0.6684 | 0.0382 | |
| GSE53622 | NPW | 283869 | 68661 | 0.1283 | 0.0126 | |
| GSE53624 | NPW | 283869 | 68661 | 0.2526 | 0.0000 | |
| GSE63941 | NPW | 283869 | 243110_x_at | 0.7611 | 0.3627 | |
| GSE77861 | NPW | 283869 | 243110_x_at | 0.2909 | 0.1012 | |
| GSE97050 | NPW | 283869 | A_23_P352799 | 0.3334 | 0.2827 | |
| SRP133303 | NPW | 283869 | RNAseq | 2.7371 | 0.0000 | |
| SRP159526 | NPW | 283869 | RNAseq | 2.9640 | 0.0002 | |
| SRP219564 | NPW | 283869 | RNAseq | 4.1482 | 0.0000 | |
| TCGA | NPW | 283869 | RNAseq | 0.6785 | 0.0156 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by NPW expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NPW:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NPW | 283869 | 5 | 5 | 20 | |
| GSE20123 | NPW | 283869 | 5 | 4 | 21 | |
| GSE43470 | NPW | 283869 | 4 | 7 | 32 | |
| GSE46452 | NPW | 283869 | 38 | 1 | 20 | |
| GSE47630 | NPW | 283869 | 13 | 6 | 21 | |
| GSE54993 | NPW | 283869 | 3 | 5 | 62 | |
| GSE54994 | NPW | 283869 | 5 | 9 | 39 | |
| GSE60625 | NPW | 283869 | 4 | 0 | 7 | |
| GSE74703 | NPW | 283869 | 4 | 5 | 27 | |
| GSE74704 | NPW | 283869 | 3 | 2 | 15 | |
| TCGA | NPW | 283869 | 19 | 14 | 63 |
Total number of gains: 103; Total number of losses: 58; Total Number of normals: 327.
Somatic mutations of NPW:
Generating mutation plots.
Highly correlated genes for NPW:
Showing top 20/335 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NPW | ASTN2 | 0.807256 | 3 | 0 | 3 |
| NPW | TUBAL3 | 0.798314 | 3 | 0 | 3 |
| NPW | NPL | 0.783002 | 3 | 0 | 3 |
| NPW | METTL4 | 0.779894 | 3 | 0 | 3 |
| NPW | TIGD5 | 0.777022 | 3 | 0 | 3 |
| NPW | WDR90 | 0.770432 | 3 | 0 | 3 |
| NPW | POLD1 | 0.765913 | 3 | 0 | 3 |
| NPW | DUSP9 | 0.764108 | 5 | 0 | 5 |
| NPW | PROC | 0.763896 | 4 | 0 | 3 |
| NPW | KIF26B | 0.760921 | 3 | 0 | 3 |
| NPW | ARHGAP22 | 0.756031 | 3 | 0 | 3 |
| NPW | SIRPA | 0.755653 | 3 | 0 | 3 |
| NPW | SPATA2L | 0.75146 | 4 | 0 | 3 |
| NPW | MARVELD3 | 0.751198 | 4 | 0 | 4 |
| NPW | AMPD2 | 0.750516 | 3 | 0 | 3 |
| NPW | TTC32 | 0.740829 | 3 | 0 | 3 |
| NPW | NR2E1 | 0.738485 | 3 | 0 | 3 |
| NPW | NUDT1 | 0.736611 | 4 | 0 | 4 |
| NPW | HOXA11 | 0.736236 | 4 | 0 | 4 |
| NPW | ASPHD1 | 0.733305 | 4 | 0 | 4 |
For details and further investigation, click here
