| Full name: myelin associated glycoprotein | Alias Symbol: SIGLEC4A|SIGLEC-4A|S-MAG | ||
| Type: protein-coding gene | Cytoband: 19q13.1 | ||
| Entrez ID: 4099 | HGNC ID: HGNC:6783 | Ensembl Gene: ENSG00000105695 | OMIM ID: 159460 |
| Drug and gene relationship at DGIdb | |||
Expression of MAG:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MAG | 4099 | 217447_at | -0.0081 | 0.9816 | |
| GSE20347 | MAG | 4099 | 216617_s_at | -0.0795 | 0.1882 | |
| GSE23400 | MAG | 4099 | 217447_at | -0.0513 | 0.0673 | |
| GSE26886 | MAG | 4099 | 216617_s_at | 0.3611 | 0.0384 | |
| GSE29001 | MAG | 4099 | 217447_at | -0.0501 | 0.7310 | |
| GSE38129 | MAG | 4099 | 216617_s_at | -0.1651 | 0.0209 | |
| GSE45670 | MAG | 4099 | 217447_at | 0.0605 | 0.4640 | |
| GSE53622 | MAG | 4099 | 31007 | 0.0273 | 0.7044 | |
| GSE53624 | MAG | 4099 | 31007 | -0.1639 | 0.0715 | |
| GSE63941 | MAG | 4099 | 216617_s_at | -0.1263 | 0.3657 | |
| GSE77861 | MAG | 4099 | 216617_s_at | -0.1291 | 0.5320 | |
| GSE97050 | MAG | 4099 | A_33_P3272823 | 0.1116 | 0.6072 | |
| TCGA | MAG | 4099 | RNAseq | -0.2048 | 0.8892 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MAG expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MAG:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MAG | 4099 | 6 | 4 | 20 | |
| GSE20123 | MAG | 4099 | 6 | 3 | 21 | |
| GSE43470 | MAG | 4099 | 3 | 7 | 33 | |
| GSE46452 | MAG | 4099 | 48 | 1 | 10 | |
| GSE47630 | MAG | 4099 | 9 | 5 | 26 | |
| GSE54993 | MAG | 4099 | 17 | 3 | 50 | |
| GSE54994 | MAG | 4099 | 8 | 9 | 36 | |
| GSE60625 | MAG | 4099 | 9 | 0 | 2 | |
| GSE74703 | MAG | 4099 | 3 | 4 | 29 | |
| GSE74704 | MAG | 4099 | 6 | 1 | 13 | |
| TCGA | MAG | 4099 | 21 | 11 | 64 |
Total number of gains: 136; Total number of losses: 48; Total Number of normals: 304.
Somatic mutations of MAG:
Generating mutation plots.
Highly correlated genes for MAG:
Showing top 20/922 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MAG | C19orf81 | 0.803167 | 3 | 0 | 3 |
| MAG | AOC2 | 0.791933 | 3 | 0 | 3 |
| MAG | TMEM179 | 0.791856 | 4 | 0 | 4 |
| MAG | KATNAL2 | 0.789876 | 3 | 0 | 3 |
| MAG | SP8 | 0.780635 | 3 | 0 | 3 |
| MAG | LCN9 | 0.777343 | 3 | 0 | 3 |
| MAG | DAB1 | 0.772285 | 4 | 0 | 4 |
| MAG | CHST10 | 0.769615 | 3 | 0 | 3 |
| MAG | UFSP1 | 0.76933 | 3 | 0 | 3 |
| MAG | ARMC5 | 0.768258 | 4 | 0 | 4 |
| MAG | ASRGL1 | 0.767616 | 3 | 0 | 3 |
| MAG | PVALB | 0.762104 | 5 | 0 | 5 |
| MAG | ATCAY | 0.759883 | 3 | 0 | 3 |
| MAG | GPHA2 | 0.759395 | 3 | 0 | 3 |
| MAG | CDC34 | 0.754234 | 3 | 0 | 3 |
| MAG | OR5A1 | 0.749233 | 3 | 0 | 3 |
| MAG | TTLL9 | 0.748018 | 4 | 0 | 3 |
| MAG | C10orf91 | 0.74482 | 4 | 0 | 4 |
| MAG | BSX | 0.743989 | 3 | 0 | 3 |
| MAG | RAD52 | 0.738986 | 4 | 0 | 4 |
For details and further investigation, click here
