| Full name: N-acetyltransferase 8B (putative, gene/pseudogene) | Alias Symbol: Hcml2|NAT8BP|CML2 | ||
| Type: protein-coding gene | Cytoband: 2p13.1 | ||
| Entrez ID: 51471 | HGNC ID: HGNC:30235 | Ensembl Gene: ENSG00000204872 | OMIM ID: 608190 |
| Drug and gene relationship at DGIdb | |||
Expression of NAT8B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NAT8B | 51471 | 206964_at | 0.1342 | 0.5844 | |
| GSE20347 | NAT8B | 51471 | 206964_at | 0.0277 | 0.6990 | |
| GSE23400 | NAT8B | 51471 | 206964_at | -0.0995 | 0.0028 | |
| GSE26886 | NAT8B | 51471 | 206964_at | 0.0906 | 0.3748 | |
| GSE29001 | NAT8B | 51471 | 206964_at | 0.1743 | 0.1612 | |
| GSE38129 | NAT8B | 51471 | 206964_at | 0.0569 | 0.5902 | |
| GSE45670 | NAT8B | 51471 | 206964_at | 0.0339 | 0.7630 | |
| GSE63941 | NAT8B | 51471 | 206964_at | -0.0928 | 0.5637 | |
| GSE77861 | NAT8B | 51471 | 206964_at | -0.0374 | 0.8132 | |
| GSE97050 | NAT8B | 51471 | A_24_P308506 | 0.1239 | 0.5830 | |
| TCGA | NAT8B | 51471 | RNAseq | -1.9722 | 0.0030 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by NAT8B expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of NAT8B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NAT8B | 51471 | 10 | 1 | 19 | |
| GSE20123 | NAT8B | 51471 | 10 | 1 | 19 | |
| GSE43470 | NAT8B | 51471 | 4 | 0 | 39 | |
| GSE46452 | NAT8B | 51471 | 2 | 3 | 54 | |
| GSE47630 | NAT8B | 51471 | 7 | 0 | 33 | |
| GSE54993 | NAT8B | 51471 | 0 | 6 | 64 | |
| GSE54994 | NAT8B | 51471 | 11 | 0 | 42 | |
| GSE60625 | NAT8B | 51471 | 0 | 3 | 8 | |
| GSE74703 | NAT8B | 51471 | 4 | 0 | 32 | |
| GSE74704 | NAT8B | 51471 | 8 | 0 | 12 |
Total number of gains: 56; Total number of losses: 14; Total Number of normals: 322.
Somatic mutations of NAT8B:
Generating mutation plots.
Highly correlated genes for NAT8B:
Showing top 20/279 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NAT8B | C19orf81 | 0.846685 | 3 | 0 | 3 |
| NAT8B | SLC26A1 | 0.818938 | 3 | 0 | 3 |
| NAT8B | DGCR6L | 0.789584 | 4 | 0 | 4 |
| NAT8B | CA4 | 0.76664 | 3 | 0 | 3 |
| NAT8B | MBD6 | 0.766396 | 3 | 0 | 3 |
| NAT8B | CPNE9 | 0.761083 | 3 | 0 | 3 |
| NAT8B | ATAD3C | 0.756432 | 3 | 0 | 3 |
| NAT8B | HIVEP2 | 0.753195 | 3 | 0 | 3 |
| NAT8B | PGBD2 | 0.748698 | 3 | 0 | 3 |
| NAT8B | ASPHD1 | 0.747614 | 3 | 0 | 3 |
| NAT8B | GALR2 | 0.739614 | 3 | 0 | 3 |
| NAT8B | RAD52 | 0.739522 | 3 | 0 | 3 |
| NAT8B | DDC | 0.723239 | 3 | 0 | 3 |
| NAT8B | SIGLEC11 | 0.720211 | 3 | 0 | 3 |
| NAT8B | PKLR | 0.719898 | 5 | 0 | 4 |
| NAT8B | FBXO24 | 0.717941 | 3 | 0 | 3 |
| NAT8B | PSPN | 0.713282 | 3 | 0 | 3 |
| NAT8B | DUSP15 | 0.713042 | 3 | 0 | 3 |
| NAT8B | CDHR5 | 0.711152 | 4 | 0 | 3 |
| NAT8B | RGS12 | 0.709664 | 3 | 0 | 3 |
For details and further investigation, click here
