| Full name: WD repeat domain 90 | Alias Symbol: FLJ36483|KIAA1924 | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 197335 | HGNC ID: HGNC:26960 | Ensembl Gene: ENSG00000161996 | OMIM ID: 618290 |
| Drug and gene relationship at DGIdb | |||
Expression of WDR90:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WDR90 | 197335 | 227894_at | 0.5492 | 0.1948 | |
| GSE26886 | WDR90 | 197335 | 227894_at | 0.9147 | 0.0001 | |
| GSE45670 | WDR90 | 197335 | 227894_at | 0.5839 | 0.0084 | |
| GSE53622 | WDR90 | 197335 | 11401 | 0.7201 | 0.0000 | |
| GSE53624 | WDR90 | 197335 | 11401 | 0.9435 | 0.0000 | |
| GSE63941 | WDR90 | 197335 | 227894_at | 0.6222 | 0.0842 | |
| GSE77861 | WDR90 | 197335 | 236049_at | 0.0540 | 0.6813 | |
| GSE97050 | WDR90 | 197335 | A_33_P3415491 | 0.3101 | 0.2092 | |
| SRP007169 | WDR90 | 197335 | RNAseq | 0.7074 | 0.1009 | |
| SRP008496 | WDR90 | 197335 | RNAseq | 0.3793 | 0.3635 | |
| SRP064894 | WDR90 | 197335 | RNAseq | 0.9607 | 0.0003 | |
| SRP133303 | WDR90 | 197335 | RNAseq | 0.5721 | 0.0150 | |
| SRP159526 | WDR90 | 197335 | RNAseq | 1.0299 | 0.0089 | |
| SRP193095 | WDR90 | 197335 | RNAseq | 0.9166 | 0.0000 | |
| SRP219564 | WDR90 | 197335 | RNAseq | 0.6593 | 0.0477 | |
| TCGA | WDR90 | 197335 | RNAseq | 0.1448 | 0.0301 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by WDR90 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WDR90:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WDR90 | 197335 | 5 | 5 | 20 | |
| GSE20123 | WDR90 | 197335 | 5 | 4 | 21 | |
| GSE43470 | WDR90 | 197335 | 4 | 7 | 32 | |
| GSE46452 | WDR90 | 197335 | 38 | 1 | 20 | |
| GSE47630 | WDR90 | 197335 | 13 | 6 | 21 | |
| GSE54993 | WDR90 | 197335 | 3 | 5 | 62 | |
| GSE54994 | WDR90 | 197335 | 4 | 10 | 39 | |
| GSE60625 | WDR90 | 197335 | 4 | 0 | 7 | |
| GSE74703 | WDR90 | 197335 | 4 | 5 | 27 | |
| GSE74704 | WDR90 | 197335 | 3 | 2 | 15 | |
| TCGA | WDR90 | 197335 | 20 | 15 | 61 |
Total number of gains: 103; Total number of losses: 60; Total Number of normals: 325.
Somatic mutations of WDR90:
Generating mutation plots.
Highly correlated genes for WDR90:
Showing top 20/493 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WDR90 | PNMA6A | 0.851624 | 3 | 0 | 3 |
| WDR90 | EVX1 | 0.810616 | 3 | 0 | 3 |
| WDR90 | RIN1 | 0.800075 | 3 | 0 | 3 |
| WDR90 | RASL10B | 0.793868 | 3 | 0 | 3 |
| WDR90 | NPW | 0.770432 | 3 | 0 | 3 |
| WDR90 | GRIN1 | 0.763534 | 3 | 0 | 3 |
| WDR90 | ZNF182 | 0.751667 | 3 | 0 | 3 |
| WDR90 | LIM2 | 0.75139 | 3 | 0 | 3 |
| WDR90 | DBF4B | 0.748039 | 3 | 0 | 3 |
| WDR90 | ZNF646 | 0.738162 | 3 | 0 | 3 |
| WDR90 | FBRSL1 | 0.737506 | 4 | 0 | 4 |
| WDR90 | ZNF341 | 0.735825 | 3 | 0 | 3 |
| WDR90 | C19orf81 | 0.734753 | 3 | 0 | 3 |
| WDR90 | MAG | 0.733818 | 3 | 0 | 3 |
| WDR90 | FUT7 | 0.732988 | 4 | 0 | 4 |
| WDR90 | LRFN4 | 0.731621 | 5 | 0 | 4 |
| WDR90 | TONSL | 0.731532 | 3 | 0 | 3 |
| WDR90 | STAC3 | 0.720982 | 4 | 0 | 3 |
| WDR90 | TMEM59L | 0.713673 | 3 | 0 | 3 |
| WDR90 | TRAIP | 0.713624 | 4 | 0 | 4 |
For details and further investigation, click here
