| Full name: ataxin 7 | Alias Symbol: OPCA3|ADCAII|SGF73 | ||
| Type: protein-coding gene | Cytoband: 3p14.1 | ||
| Entrez ID: 6314 | HGNC ID: HGNC:10560 | Ensembl Gene: ENSG00000163635 | OMIM ID: 607640 |
| Drug and gene relationship at DGIdb | |||
Expression of ATXN7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATXN7 | 6314 | 204516_at | -0.2460 | 0.4767 | |
| GSE20347 | ATXN7 | 6314 | 204516_at | -0.6570 | 0.0035 | |
| GSE23400 | ATXN7 | 6314 | 209964_s_at | -0.4081 | 0.0000 | |
| GSE26886 | ATXN7 | 6314 | 204516_at | -1.5981 | 0.0000 | |
| GSE29001 | ATXN7 | 6314 | 204516_at | -0.5438 | 0.0638 | |
| GSE38129 | ATXN7 | 6314 | 204516_at | -0.7262 | 0.0017 | |
| GSE45670 | ATXN7 | 6314 | 204516_at | -0.4412 | 0.0027 | |
| GSE53622 | ATXN7 | 6314 | 134631 | -0.4546 | 0.0000 | |
| GSE53624 | ATXN7 | 6314 | 27033 | -0.4126 | 0.0000 | |
| GSE63941 | ATXN7 | 6314 | 204516_at | 0.1665 | 0.7489 | |
| GSE77861 | ATXN7 | 6314 | 204516_at | -0.3931 | 0.1505 | |
| GSE97050 | ATXN7 | 6314 | A_33_P3320782 | -0.3715 | 0.1505 | |
| SRP007169 | ATXN7 | 6314 | RNAseq | -0.8674 | 0.0244 | |
| SRP008496 | ATXN7 | 6314 | RNAseq | -0.7878 | 0.0001 | |
| SRP064894 | ATXN7 | 6314 | RNAseq | -0.6031 | 0.0300 | |
| SRP133303 | ATXN7 | 6314 | RNAseq | -0.3891 | 0.0030 | |
| SRP159526 | ATXN7 | 6314 | RNAseq | -0.8027 | 0.0088 | |
| SRP193095 | ATXN7 | 6314 | RNAseq | -0.4616 | 0.0000 | |
| SRP219564 | ATXN7 | 6314 | RNAseq | -0.4953 | 0.1069 | |
| TCGA | ATXN7 | 6314 | RNAseq | -0.2974 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ATXN7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATXN7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATXN7 | 6314 | 0 | 18 | 12 | |
| GSE20123 | ATXN7 | 6314 | 0 | 18 | 12 | |
| GSE43470 | ATXN7 | 6314 | 0 | 19 | 24 | |
| GSE46452 | ATXN7 | 6314 | 2 | 17 | 40 | |
| GSE47630 | ATXN7 | 6314 | 1 | 24 | 15 | |
| GSE54993 | ATXN7 | 6314 | 5 | 2 | 63 | |
| GSE54994 | ATXN7 | 6314 | 1 | 33 | 19 | |
| GSE60625 | ATXN7 | 6314 | 3 | 1 | 7 | |
| GSE74703 | ATXN7 | 6314 | 0 | 15 | 21 | |
| GSE74704 | ATXN7 | 6314 | 0 | 12 | 8 | |
| TCGA | ATXN7 | 6314 | 0 | 77 | 19 |
Total number of gains: 12; Total number of losses: 236; Total Number of normals: 240.
Somatic mutations of ATXN7:
Generating mutation plots.
Highly correlated genes for ATXN7:
Showing top 20/1208 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATXN7 | CRK | 0.772805 | 3 | 0 | 3 |
| ATXN7 | KIAA1143 | 0.75919 | 3 | 0 | 3 |
| ATXN7 | C5orf51 | 0.756745 | 3 | 0 | 3 |
| ATXN7 | TMEM167B | 0.739358 | 3 | 0 | 3 |
| ATXN7 | RSRC2 | 0.736088 | 3 | 0 | 3 |
| ATXN7 | FAM83D | 0.733399 | 3 | 0 | 3 |
| ATXN7 | MALT1 | 0.732963 | 3 | 0 | 3 |
| ATXN7 | ETFA | 0.73188 | 4 | 0 | 3 |
| ATXN7 | ZNF565 | 0.722979 | 3 | 0 | 3 |
| ATXN7 | LYSMD3 | 0.72173 | 3 | 0 | 3 |
| ATXN7 | ZNF354C | 0.718093 | 3 | 0 | 3 |
| ATXN7 | SPA17 | 0.71616 | 3 | 0 | 3 |
| ATXN7 | ZNF92 | 0.714097 | 3 | 0 | 3 |
| ATXN7 | PBRM1 | 0.713169 | 11 | 0 | 9 |
| ATXN7 | DOCK8 | 0.712914 | 5 | 0 | 5 |
| ATXN7 | RPS11 | 0.710696 | 4 | 0 | 4 |
| ATXN7 | BRWD3 | 0.71057 | 3 | 0 | 3 |
| ATXN7 | PSMD6-AS2 | 0.710538 | 6 | 0 | 4 |
| ATXN7 | SS18 | 0.71035 | 5 | 0 | 4 |
| ATXN7 | HDHD2 | 0.708248 | 5 | 0 | 4 |
For details and further investigation, click here
