| Full name: LysM domain containing 3 | Alias Symbol: FLJ13542 | ||
| Type: protein-coding gene | Cytoband: 5q14.3 | ||
| Entrez ID: 116068 | HGNC ID: HGNC:26969 | Ensembl Gene: ENSG00000176018 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LYSMD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LYSMD3 | 116068 | 226321_at | -0.4199 | 0.3166 | |
| GSE26886 | LYSMD3 | 116068 | 226321_at | -1.4676 | 0.0000 | |
| GSE45670 | LYSMD3 | 116068 | 226321_at | -0.1490 | 0.3783 | |
| GSE53622 | LYSMD3 | 116068 | 130036 | -0.4525 | 0.0000 | |
| GSE53624 | LYSMD3 | 116068 | 130036 | -0.6960 | 0.0000 | |
| GSE63941 | LYSMD3 | 116068 | 226321_at | -1.2898 | 0.0011 | |
| GSE77861 | LYSMD3 | 116068 | 226321_at | -0.6447 | 0.0523 | |
| GSE97050 | LYSMD3 | 116068 | A_24_P15658 | 0.0456 | 0.9216 | |
| SRP007169 | LYSMD3 | 116068 | RNAseq | -0.7409 | 0.0936 | |
| SRP008496 | LYSMD3 | 116068 | RNAseq | -0.9180 | 0.0003 | |
| SRP064894 | LYSMD3 | 116068 | RNAseq | -0.5575 | 0.0280 | |
| SRP133303 | LYSMD3 | 116068 | RNAseq | 0.1296 | 0.5398 | |
| SRP159526 | LYSMD3 | 116068 | RNAseq | -0.5794 | 0.0130 | |
| SRP193095 | LYSMD3 | 116068 | RNAseq | -0.8560 | 0.0000 | |
| SRP219564 | LYSMD3 | 116068 | RNAseq | -0.6681 | 0.0658 | |
| TCGA | LYSMD3 | 116068 | RNAseq | -0.1833 | 0.0006 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by LYSMD3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LYSMD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LYSMD3 | 116068 | 1 | 14 | 15 | |
| GSE20123 | LYSMD3 | 116068 | 1 | 14 | 15 | |
| GSE43470 | LYSMD3 | 116068 | 2 | 10 | 31 | |
| GSE46452 | LYSMD3 | 116068 | 0 | 28 | 31 | |
| GSE47630 | LYSMD3 | 116068 | 1 | 20 | 19 | |
| GSE54993 | LYSMD3 | 116068 | 8 | 1 | 61 | |
| GSE54994 | LYSMD3 | 116068 | 1 | 18 | 34 | |
| GSE60625 | LYSMD3 | 116068 | 0 | 0 | 11 | |
| GSE74703 | LYSMD3 | 116068 | 1 | 8 | 27 | |
| GSE74704 | LYSMD3 | 116068 | 1 | 7 | 12 | |
| TCGA | LYSMD3 | 116068 | 2 | 50 | 44 |
Total number of gains: 18; Total number of losses: 170; Total Number of normals: 300.
Somatic mutations of LYSMD3:
Generating mutation plots.
Highly correlated genes for LYSMD3:
Showing top 20/1091 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LYSMD3 | EPG5 | 0.847681 | 4 | 0 | 4 |
| LYSMD3 | IMPACT | 0.825121 | 3 | 0 | 3 |
| LYSMD3 | CRBN | 0.80353 | 3 | 0 | 3 |
| LYSMD3 | PTCD2 | 0.800745 | 3 | 0 | 3 |
| LYSMD3 | FPGT | 0.794309 | 3 | 0 | 3 |
| LYSMD3 | TMEM19 | 0.785022 | 4 | 0 | 4 |
| LYSMD3 | ZNF585A | 0.78096 | 3 | 0 | 3 |
| LYSMD3 | CAMK2D | 0.778899 | 3 | 0 | 3 |
| LYSMD3 | EIF3I | 0.775685 | 3 | 0 | 3 |
| LYSMD3 | ZDHHC21 | 0.774025 | 4 | 0 | 4 |
| LYSMD3 | DPY19L3 | 0.774 | 3 | 0 | 3 |
| LYSMD3 | ANGPTL4 | 0.771803 | 3 | 0 | 3 |
| LYSMD3 | CCNYL1 | 0.771477 | 4 | 0 | 4 |
| LYSMD3 | ZNF844 | 0.771171 | 4 | 0 | 4 |
| LYSMD3 | SEMA6A | 0.76929 | 3 | 0 | 3 |
| LYSMD3 | TRAPPC6B | 0.768919 | 3 | 0 | 3 |
| LYSMD3 | PFKFB2 | 0.768792 | 3 | 0 | 3 |
| LYSMD3 | TET2 | 0.767781 | 3 | 0 | 3 |
| LYSMD3 | KDM5D | 0.76651 | 3 | 0 | 3 |
| LYSMD3 | B3GNT2 | 0.763796 | 4 | 0 | 4 |
For details and further investigation, click here
