| Full name: family with sequence similarity 83 member D | Alias Symbol: dJ616B8.3|CHICA | ||
| Type: protein-coding gene | Cytoband: 20q11.23 | ||
| Entrez ID: 81610 | HGNC ID: HGNC:16122 | Ensembl Gene: ENSG00000101447 | OMIM ID: 618380 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of FAM83D:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM83D | 81610 | 225687_at | -0.8744 | 0.2880 | |
| GSE26886 | FAM83D | 81610 | 225687_at | -2.1036 | 0.0000 | |
| GSE45670 | FAM83D | 81610 | 225687_at | -0.2608 | 0.4516 | |
| GSE53622 | FAM83D | 81610 | 115035 | -0.4990 | 0.0047 | |
| GSE53624 | FAM83D | 81610 | 115035 | -1.0241 | 0.0000 | |
| GSE63941 | FAM83D | 81610 | 225687_at | 3.8463 | 0.0000 | |
| GSE77861 | FAM83D | 81610 | 225687_at | -1.1991 | 0.0046 | |
| GSE97050 | FAM83D | 81610 | A_23_P323751 | -0.7394 | 0.1403 | |
| SRP007169 | FAM83D | 81610 | RNAseq | -0.7980 | 0.0442 | |
| SRP008496 | FAM83D | 81610 | RNAseq | -1.0907 | 0.0001 | |
| SRP064894 | FAM83D | 81610 | RNAseq | -0.3939 | 0.2287 | |
| SRP133303 | FAM83D | 81610 | RNAseq | 0.0795 | 0.8559 | |
| SRP159526 | FAM83D | 81610 | RNAseq | -0.2365 | 0.6057 | |
| SRP193095 | FAM83D | 81610 | RNAseq | -1.2907 | 0.0000 | |
| SRP219564 | FAM83D | 81610 | RNAseq | -0.9281 | 0.2174 | |
| TCGA | FAM83D | 81610 | RNAseq | 0.1779 | 0.0752 |
Upregulated datasets: 1; Downregulated datasets: 5.
Survival by FAM83D expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM83D:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM83D | 81610 | 14 | 2 | 14 | |
| GSE20123 | FAM83D | 81610 | 14 | 2 | 14 | |
| GSE43470 | FAM83D | 81610 | 13 | 0 | 30 | |
| GSE46452 | FAM83D | 81610 | 29 | 0 | 30 | |
| GSE47630 | FAM83D | 81610 | 24 | 0 | 16 | |
| GSE54993 | FAM83D | 81610 | 0 | 17 | 53 | |
| GSE54994 | FAM83D | 81610 | 24 | 0 | 29 | |
| GSE60625 | FAM83D | 81610 | 0 | 0 | 11 | |
| GSE74703 | FAM83D | 81610 | 10 | 0 | 26 | |
| GSE74704 | FAM83D | 81610 | 10 | 1 | 9 | |
| TCGA | FAM83D | 81610 | 47 | 4 | 45 |
Total number of gains: 185; Total number of losses: 26; Total Number of normals: 277.
Somatic mutations of FAM83D:
Generating mutation plots.
Highly correlated genes for FAM83D:
Showing top 20/904 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM83D | LSM11 | 0.849356 | 3 | 0 | 3 |
| FAM83D | UBE2J1 | 0.846347 | 3 | 0 | 3 |
| FAM83D | DCAF10 | 0.825653 | 3 | 0 | 3 |
| FAM83D | NKX6-1 | 0.789509 | 3 | 0 | 3 |
| FAM83D | TYSND1 | 0.78477 | 3 | 0 | 3 |
| FAM83D | OXSM | 0.783617 | 3 | 0 | 3 |
| FAM83D | GLTP | 0.78258 | 4 | 0 | 4 |
| FAM83D | APEH | 0.781299 | 3 | 0 | 3 |
| FAM83D | PNRC2 | 0.77191 | 4 | 0 | 4 |
| FAM83D | METTL9 | 0.767602 | 3 | 0 | 3 |
| FAM83D | ZFAND6 | 0.759315 | 4 | 0 | 4 |
| FAM83D | PKN2 | 0.75886 | 4 | 0 | 4 |
| FAM83D | CAMK2G | 0.75852 | 3 | 0 | 3 |
| FAM83D | SPTLC3 | 0.753454 | 3 | 0 | 3 |
| FAM83D | NAA35 | 0.752791 | 3 | 0 | 3 |
| FAM83D | NGLY1 | 0.752183 | 3 | 0 | 3 |
| FAM83D | ARG2 | 0.750512 | 3 | 0 | 3 |
| FAM83D | SNAPC3 | 0.748218 | 3 | 0 | 3 |
| FAM83D | RAP1A | 0.747067 | 5 | 0 | 5 |
| FAM83D | RASSF3 | 0.743545 | 3 | 0 | 3 |
For details and further investigation, click here
