| Full name: SS18 subunit of BAF chromatin remodeling complex | Alias Symbol: SYT | ||
| Type: protein-coding gene | Cytoband: 18q11.2 | ||
| Entrez ID: 6760 | HGNC ID: HGNC:11340 | Ensembl Gene: | OMIM ID: 600192 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SS18:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SS18 | 6760 | 202816_s_at | -0.2288 | 0.5859 | |
| GSE20347 | SS18 | 6760 | 202816_s_at | -0.3050 | 0.0845 | |
| GSE23400 | SS18 | 6760 | 209954_x_at | -0.0988 | 0.0463 | |
| GSE26886 | SS18 | 6760 | 202816_s_at | -0.8405 | 0.0022 | |
| GSE29001 | SS18 | 6760 | 202816_s_at | -0.5095 | 0.2132 | |
| GSE38129 | SS18 | 6760 | 202816_s_at | 0.2968 | 0.2043 | |
| GSE45670 | SS18 | 6760 | 202817_s_at | -0.1696 | 0.3117 | |
| GSE53622 | SS18 | 6760 | 2439 | 0.0482 | 0.3859 | |
| GSE53624 | SS18 | 6760 | 2439 | -0.0659 | 0.4793 | |
| GSE63941 | SS18 | 6760 | 202816_s_at | -0.2109 | 0.6248 | |
| GSE77861 | SS18 | 6760 | 202816_s_at | 0.3277 | 0.5668 | |
| GSE97050 | SS18 | 6760 | A_23_P141738 | 0.2591 | 0.2239 | |
| SRP007169 | SS18 | 6760 | RNAseq | 0.4485 | 0.2480 | |
| SRP008496 | SS18 | 6760 | RNAseq | 0.4173 | 0.0830 | |
| SRP064894 | SS18 | 6760 | RNAseq | -0.1082 | 0.4764 | |
| SRP133303 | SS18 | 6760 | RNAseq | 0.1384 | 0.4344 | |
| SRP159526 | SS18 | 6760 | RNAseq | -0.1006 | 0.6439 | |
| SRP193095 | SS18 | 6760 | RNAseq | -0.1788 | 0.0712 | |
| SRP219564 | SS18 | 6760 | RNAseq | -0.0942 | 0.5828 | |
| TCGA | SS18 | 6760 | RNAseq | 0.0029 | 0.9500 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SS18 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SS18:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SS18 | 6760 | 1 | 6 | 23 | |
| GSE20123 | SS18 | 6760 | 1 | 6 | 23 | |
| GSE43470 | SS18 | 6760 | 1 | 2 | 40 | |
| GSE46452 | SS18 | 6760 | 1 | 25 | 33 | |
| GSE47630 | SS18 | 6760 | 6 | 19 | 15 | |
| GSE54993 | SS18 | 6760 | 7 | 1 | 62 | |
| GSE54994 | SS18 | 6760 | 3 | 14 | 36 | |
| GSE60625 | SS18 | 6760 | 0 | 4 | 7 | |
| GSE74703 | SS18 | 6760 | 1 | 2 | 33 | |
| GSE74704 | SS18 | 6760 | 1 | 5 | 14 | |
| TCGA | SS18 | 6760 | 15 | 33 | 48 |
Total number of gains: 37; Total number of losses: 117; Total Number of normals: 334.
Somatic mutations of SS18:
Generating mutation plots.
Highly correlated genes for SS18:
Showing top 20/519 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SS18 | AKAP17A | 0.844132 | 3 | 0 | 3 |
| SS18 | PPM1D | 0.792622 | 3 | 0 | 3 |
| SS18 | KIAA1586 | 0.775293 | 3 | 0 | 3 |
| SS18 | TMX3 | 0.76387 | 3 | 0 | 3 |
| SS18 | DMTF1 | 0.761987 | 3 | 0 | 3 |
| SS18 | DPAGT1 | 0.754036 | 3 | 0 | 3 |
| SS18 | BLOC1S2 | 0.752319 | 3 | 0 | 3 |
| SS18 | ANKHD1 | 0.750475 | 3 | 0 | 3 |
| SS18 | ZCCHC10 | 0.750028 | 3 | 0 | 3 |
| SS18 | KLHL20 | 0.749136 | 3 | 0 | 3 |
| SS18 | MCPH1 | 0.748292 | 3 | 0 | 3 |
| SS18 | EZH2 | 0.746621 | 3 | 0 | 3 |
| SS18 | UBQLN1 | 0.746327 | 3 | 0 | 3 |
| SS18 | RINT1 | 0.743535 | 5 | 0 | 5 |
| SS18 | RGS10 | 0.742174 | 3 | 0 | 3 |
| SS18 | RB1CC1 | 0.735466 | 3 | 0 | 3 |
| SS18 | MYL12B | 0.733317 | 3 | 0 | 3 |
| SS18 | UBE2J1 | 0.732911 | 4 | 0 | 4 |
| SS18 | SLC46A2 | 0.731807 | 3 | 0 | 3 |
| SS18 | KRCC1 | 0.730712 | 3 | 0 | 3 |
For details and further investigation, click here
