| Full name: sperm autoantigenic protein 17 | Alias Symbol: SP17|CT22 | ||
| Type: protein-coding gene | Cytoband: 11q24.2 | ||
| Entrez ID: 53340 | HGNC ID: HGNC:11210 | Ensembl Gene: ENSG00000064199 | OMIM ID: 608621 |
| Drug and gene relationship at DGIdb | |||
Expression of SPA17:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SPA17 | 53340 | 205406_s_at | -0.1226 | 0.8436 | |
| GSE20347 | SPA17 | 53340 | 205406_s_at | -0.5069 | 0.0449 | |
| GSE23400 | SPA17 | 53340 | 205406_s_at | -0.0002 | 0.9976 | |
| GSE26886 | SPA17 | 53340 | 205406_s_at | 0.2964 | 0.3973 | |
| GSE29001 | SPA17 | 53340 | 205406_s_at | -0.2597 | 0.3268 | |
| GSE38129 | SPA17 | 53340 | 205406_s_at | -0.1810 | 0.4087 | |
| GSE45670 | SPA17 | 53340 | 205406_s_at | 0.3274 | 0.1304 | |
| GSE53622 | SPA17 | 53340 | 40547 | 0.1510 | 0.0805 | |
| GSE53624 | SPA17 | 53340 | 40547 | -0.0692 | 0.3646 | |
| GSE63941 | SPA17 | 53340 | 205406_s_at | -1.2170 | 0.1886 | |
| GSE77861 | SPA17 | 53340 | 205406_s_at | 0.0959 | 0.7807 | |
| GSE97050 | SPA17 | 53340 | A_23_P104876 | 0.0596 | 0.8236 | |
| SRP064894 | SPA17 | 53340 | RNAseq | -0.0887 | 0.6865 | |
| SRP133303 | SPA17 | 53340 | RNAseq | -0.0528 | 0.8774 | |
| SRP159526 | SPA17 | 53340 | RNAseq | -0.2702 | 0.4052 | |
| SRP193095 | SPA17 | 53340 | RNAseq | -0.4544 | 0.0215 | |
| SRP219564 | SPA17 | 53340 | RNAseq | -0.4867 | 0.1000 | |
| TCGA | SPA17 | 53340 | RNAseq | 0.1389 | 0.2928 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SPA17 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SPA17:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPA17 | 53340 | 0 | 13 | 17 | |
| GSE20123 | SPA17 | 53340 | 0 | 13 | 17 | |
| GSE43470 | SPA17 | 53340 | 2 | 7 | 34 | |
| GSE46452 | SPA17 | 53340 | 3 | 26 | 30 | |
| GSE47630 | SPA17 | 53340 | 2 | 19 | 19 | |
| GSE54993 | SPA17 | 53340 | 10 | 0 | 60 | |
| GSE54994 | SPA17 | 53340 | 5 | 19 | 29 | |
| GSE60625 | SPA17 | 53340 | 0 | 3 | 8 | |
| GSE74703 | SPA17 | 53340 | 1 | 5 | 30 | |
| GSE74704 | SPA17 | 53340 | 0 | 9 | 11 | |
| TCGA | SPA17 | 53340 | 6 | 50 | 40 |
Total number of gains: 29; Total number of losses: 164; Total Number of normals: 295.
Somatic mutations of SPA17:
Generating mutation plots.
Highly correlated genes for SPA17:
Showing top 20/128 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPA17 | TRIM5 | 0.805805 | 3 | 0 | 3 |
| SPA17 | LAMTOR3 | 0.769906 | 3 | 0 | 3 |
| SPA17 | CNOT2 | 0.754015 | 3 | 0 | 3 |
| SPA17 | ZNF140 | 0.739712 | 3 | 0 | 3 |
| SPA17 | CRIM1 | 0.722726 | 3 | 0 | 3 |
| SPA17 | ATXN7 | 0.71616 | 3 | 0 | 3 |
| SPA17 | UFC1 | 0.715961 | 3 | 0 | 3 |
| SPA17 | NR2C2 | 0.715155 | 3 | 0 | 3 |
| SPA17 | MBD2 | 0.709081 | 3 | 0 | 3 |
| SPA17 | DNAJC28 | 0.706426 | 3 | 0 | 3 |
| SPA17 | TRAPPC2L | 0.70193 | 3 | 0 | 3 |
| SPA17 | TMEM181 | 0.701907 | 3 | 0 | 3 |
| SPA17 | ORC5 | 0.700696 | 3 | 0 | 3 |
| SPA17 | MRPL16 | 0.696837 | 4 | 0 | 3 |
| SPA17 | SLC35D2 | 0.694247 | 3 | 0 | 3 |
| SPA17 | CHD1 | 0.693936 | 3 | 0 | 3 |
| SPA17 | CD164 | 0.691028 | 3 | 0 | 3 |
| SPA17 | UBE2L3 | 0.690593 | 3 | 0 | 3 |
| SPA17 | ZNF322 | 0.687057 | 3 | 0 | 3 |
| SPA17 | SYNJ1 | 0.685939 | 3 | 0 | 3 |
For details and further investigation, click here
