C1orf158

 

Full name: chromosome 1 open reading frame 158 Alias Symbol: MGC35194
Type: protein-coding gene Cytoband: 1p36.21
Entrez ID: 93190 HGNC ID: HGNC:28567 Ensembl Gene: ENSG00000157330 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of C1orf158:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 C1orf158 93190 231549_at 0.0985 0.6940
GSE26886 C1orf158 93190 231549_at -0.0345 0.7431
GSE45670 C1orf158 93190 231549_at -0.0192 0.8497
GSE53622 C1orf158 93190 42258 -0.0153 0.8417
GSE53624 C1orf158 93190 42258 0.1710 0.1034
GSE63941 C1orf158 93190 231549_at 0.1636 0.5925
GSE77861 C1orf158 93190 231549_at -0.0297 0.8087
SRP133303 C1orf158 93190 RNAseq -0.0167 0.9058
SRP159526 C1orf158 93190 RNAseq -1.3253 0.0017
SRP193095 C1orf158 93190 RNAseq -0.1958 0.1908
TCGA C1orf158 93190 RNAseq -1.0508 0.6109

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by C1orf158 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of C1orf158:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 C1orf158 93190 0 4 26
GSE20123 C1orf158 93190 0 3 27
GSE43470 C1orf158 93190 2 6 35
GSE46452 C1orf158 93190 7 1 51
GSE47630 C1orf158 93190 8 3 29
GSE54993 C1orf158 93190 3 1 66
GSE54994 C1orf158 93190 11 4 38
GSE60625 C1orf158 93190 0 0 11
GSE74703 C1orf158 93190 2 4 30
GSE74704 C1orf158 93190 0 0 20
TCGA C1orf158 93190 11 21 64

Total number of gains: 44; Total number of losses: 47; Total Number of normals: 397.  


 

Somatic mutations of C1orf158:

 

Generating mutation plots.

 

Highly correlated genes for C1orf158:

 

Showing top 20/55 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
C1orf158OR2H10.680576303
C1orf158SLC32A10.680084303
C1orf158SLC22A60.666319303
C1orf158HOXB80.650786303
C1orf158BPIFC0.643663303
C1orf158ST8SIA6-AS10.640742303
C1orf158LINC010150.638035303
C1orf158HMGXB30.633423303
C1orf158TMEM2350.627672303
C1orf158DEFB1210.622508303
C1orf158LIN28A0.62182303
C1orf158PRLHR0.621356303
C1orf158NPHS20.62094403
C1orf158SEZ6L20.617757403
C1orf158SLC22A140.615316303
C1orf158TMEM1050.615166303
C1orf158SLC6A190.606861403
C1orf158BARHL10.603711303
C1orf158SLC5A80.60291303
C1orf158CBLN40.601514303

For details and further investigation, click here