| Full name: HMG-box containing 3 | Alias Symbol: SMF|KIAA0194 | ||
| Type: protein-coding gene | Cytoband: 5q32 | ||
| Entrez ID: 22993 | HGNC ID: HGNC:28982 | Ensembl Gene: ENSG00000113716 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of HMGXB3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HMGXB3 | 22993 | 212431_at | 0.1593 | 0.5220 | |
| GSE20347 | HMGXB3 | 22993 | 212431_at | 0.2191 | 0.0257 | |
| GSE23400 | HMGXB3 | 22993 | 212431_at | 0.0707 | 0.0514 | |
| GSE26886 | HMGXB3 | 22993 | 212431_at | 0.2240 | 0.0801 | |
| GSE29001 | HMGXB3 | 22993 | 34221_at | 0.1868 | 0.2982 | |
| GSE38129 | HMGXB3 | 22993 | 212431_at | 0.1564 | 0.0873 | |
| GSE45670 | HMGXB3 | 22993 | 212431_at | 0.1655 | 0.0170 | |
| GSE53622 | HMGXB3 | 22993 | 167460 | 0.7433 | 0.0000 | |
| GSE53624 | HMGXB3 | 22993 | 167460 | 0.7697 | 0.0000 | |
| GSE63941 | HMGXB3 | 22993 | 212431_at | 0.1850 | 0.3462 | |
| GSE77861 | HMGXB3 | 22993 | 212431_at | 0.2068 | 0.2239 | |
| GSE97050 | HMGXB3 | 22993 | A_33_P3379941 | 0.3866 | 0.2428 | |
| SRP007169 | HMGXB3 | 22993 | RNAseq | 1.1643 | 0.0015 | |
| SRP008496 | HMGXB3 | 22993 | RNAseq | 1.3492 | 0.0000 | |
| SRP064894 | HMGXB3 | 22993 | RNAseq | 0.7226 | 0.0000 | |
| SRP133303 | HMGXB3 | 22993 | RNAseq | 0.5876 | 0.0014 | |
| SRP159526 | HMGXB3 | 22993 | RNAseq | 0.8136 | 0.0049 | |
| SRP193095 | HMGXB3 | 22993 | RNAseq | 0.6199 | 0.0000 | |
| SRP219564 | HMGXB3 | 22993 | RNAseq | 0.6680 | 0.1103 | |
| TCGA | HMGXB3 | 22993 | RNAseq | -0.0602 | 0.1981 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by HMGXB3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HMGXB3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HMGXB3 | 22993 | 1 | 12 | 17 | |
| GSE20123 | HMGXB3 | 22993 | 1 | 12 | 17 | |
| GSE43470 | HMGXB3 | 22993 | 1 | 10 | 32 | |
| GSE46452 | HMGXB3 | 22993 | 0 | 27 | 32 | |
| GSE47630 | HMGXB3 | 22993 | 0 | 20 | 20 | |
| GSE54993 | HMGXB3 | 22993 | 9 | 1 | 60 | |
| GSE54994 | HMGXB3 | 22993 | 2 | 15 | 36 | |
| GSE60625 | HMGXB3 | 22993 | 0 | 0 | 11 | |
| GSE74703 | HMGXB3 | 22993 | 1 | 7 | 28 | |
| GSE74704 | HMGXB3 | 22993 | 1 | 7 | 12 | |
| TCGA | HMGXB3 | 22993 | 5 | 38 | 53 |
Total number of gains: 21; Total number of losses: 149; Total Number of normals: 318.
Somatic mutations of HMGXB3:
Generating mutation plots.
Highly correlated genes for HMGXB3:
Showing top 20/625 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HMGXB3 | RIMS4 | 0.716912 | 3 | 0 | 3 |
| HMGXB3 | UBTF | 0.697012 | 3 | 0 | 3 |
| HMGXB3 | UTP23 | 0.691862 | 3 | 0 | 3 |
| HMGXB3 | MARCKSL1 | 0.64866 | 5 | 0 | 4 |
| HMGXB3 | SLC45A3 | 0.647891 | 3 | 0 | 3 |
| HMGXB3 | ATP6V0D2 | 0.644667 | 3 | 0 | 3 |
| HMGXB3 | ZNF469 | 0.641425 | 5 | 0 | 4 |
| HMGXB3 | TNFSF18 | 0.639518 | 3 | 0 | 3 |
| HMGXB3 | GML | 0.63539 | 3 | 0 | 3 |
| HMGXB3 | C1orf158 | 0.633423 | 3 | 0 | 3 |
| HMGXB3 | FADS3 | 0.633097 | 8 | 0 | 8 |
| HMGXB3 | PTK7 | 0.631165 | 7 | 0 | 6 |
| HMGXB3 | CYP3A4 | 0.631164 | 4 | 0 | 3 |
| HMGXB3 | LRR1 | 0.630802 | 4 | 0 | 4 |
| HMGXB3 | CMTM3 | 0.628254 | 3 | 0 | 3 |
| HMGXB3 | TTC4 | 0.627309 | 3 | 0 | 3 |
| HMGXB3 | CNTROB | 0.625845 | 6 | 0 | 5 |
| HMGXB3 | ADAMTS6 | 0.625612 | 6 | 0 | 5 |
| HMGXB3 | B3GALT6 | 0.623901 | 3 | 0 | 3 |
| HMGXB3 | CD300LF | 0.622899 | 3 | 0 | 3 |
For details and further investigation, click here
