| Full name: solute carrier family 6 member 19 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 5p15.33 | ||
| Entrez ID: 340024 | HGNC ID: HGNC:27960 | Ensembl Gene: ENSG00000174358 | OMIM ID: 608893 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC6A19:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC6A19 | 340024 | 231021_at | -0.0072 | 0.9801 | |
| GSE26886 | SLC6A19 | 340024 | 231021_at | -0.0433 | 0.6849 | |
| GSE45670 | SLC6A19 | 340024 | 231021_at | 0.1150 | 0.4909 | |
| GSE53622 | SLC6A19 | 340024 | 36732 | -0.1982 | 0.0615 | |
| GSE53624 | SLC6A19 | 340024 | 36732 | -0.5355 | 0.0000 | |
| GSE63941 | SLC6A19 | 340024 | 231021_at | 0.0828 | 0.5974 | |
| GSE77861 | SLC6A19 | 340024 | 231021_at | -0.2294 | 0.0316 | |
| GSE97050 | SLC6A19 | 340024 | A_33_P3220545 | 0.0484 | 0.8375 | |
| TCGA | SLC6A19 | 340024 | RNAseq | -4.0619 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SLC6A19 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC6A19:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC6A19 | 340024 | 13 | 1 | 16 | |
| GSE20123 | SLC6A19 | 340024 | 13 | 1 | 16 | |
| GSE43470 | SLC6A19 | 340024 | 17 | 1 | 25 | |
| GSE46452 | SLC6A19 | 340024 | 6 | 22 | 31 | |
| GSE47630 | SLC6A19 | 340024 | 7 | 11 | 22 | |
| GSE54993 | SLC6A19 | 340024 | 5 | 5 | 60 | |
| GSE54994 | SLC6A19 | 340024 | 29 | 1 | 23 | |
| GSE60625 | SLC6A19 | 340024 | 0 | 0 | 11 | |
| GSE74703 | SLC6A19 | 340024 | 14 | 0 | 22 | |
| GSE74704 | SLC6A19 | 340024 | 11 | 0 | 9 | |
| TCGA | SLC6A19 | 340024 | 61 | 3 | 32 |
Total number of gains: 176; Total number of losses: 45; Total Number of normals: 267.
Somatic mutations of SLC6A19:
Generating mutation plots.
Highly correlated genes for SLC6A19:
Showing top 20/279 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC6A19 | MUC8 | 0.815642 | 3 | 0 | 3 |
| SLC6A19 | RNF180 | 0.754141 | 3 | 0 | 3 |
| SLC6A19 | LRRC71 | 0.738195 | 3 | 0 | 3 |
| SLC6A19 | OR12D3 | 0.73486 | 3 | 0 | 3 |
| SLC6A19 | FAM171A2 | 0.725075 | 3 | 0 | 3 |
| SLC6A19 | CHRNA2 | 0.72206 | 3 | 0 | 3 |
| SLC6A19 | MTUS2-AS1 | 0.721051 | 4 | 0 | 3 |
| SLC6A19 | DLK2 | 0.717371 | 3 | 0 | 3 |
| SLC6A19 | HDGFL1 | 0.709829 | 3 | 0 | 3 |
| SLC6A19 | BTNL8 | 0.709576 | 3 | 0 | 3 |
| SLC6A19 | WFIKKN2 | 0.704975 | 3 | 0 | 3 |
| SLC6A19 | GPR25 | 0.701371 | 3 | 0 | 3 |
| SLC6A19 | TNNI3 | 0.701069 | 3 | 0 | 3 |
| SLC6A19 | IL17RC | 0.696279 | 4 | 0 | 3 |
| SLC6A19 | ASGR2 | 0.695688 | 4 | 0 | 3 |
| SLC6A19 | NXF3 | 0.687658 | 3 | 0 | 3 |
| SLC6A19 | RXFP3 | 0.686425 | 3 | 0 | 3 |
| SLC6A19 | SPINT3 | 0.684706 | 3 | 0 | 3 |
| SLC6A19 | RGS12 | 0.679279 | 3 | 0 | 3 |
| SLC6A19 | ARL5C | 0.673352 | 3 | 0 | 3 |
For details and further investigation, click here
