| Full name: seizure related 6 homolog like 2 | Alias Symbol: PSK-1|FLJ90517 | ||
| Type: protein-coding gene | Cytoband: 16p11.2 | ||
| Entrez ID: 26470 | HGNC ID: HGNC:30844 | Ensembl Gene: ENSG00000174938 | OMIM ID: 616667 |
| Drug and gene relationship at DGIdb | |||
Expression of SEZ6L2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SEZ6L2 | 26470 | 238406_x_at | 0.1502 | 0.4570 | |
| GSE20347 | SEZ6L2 | 26470 | 218720_x_at | 0.4701 | 0.0196 | |
| GSE23400 | SEZ6L2 | 26470 | 218720_x_at | 0.3672 | 0.0001 | |
| GSE26886 | SEZ6L2 | 26470 | 238406_x_at | 0.2948 | 0.0087 | |
| GSE29001 | SEZ6L2 | 26470 | 218720_x_at | 0.3930 | 0.1819 | |
| GSE38129 | SEZ6L2 | 26470 | 218720_x_at | 0.6650 | 0.0039 | |
| GSE45670 | SEZ6L2 | 26470 | 238406_x_at | 0.0101 | 0.9399 | |
| GSE53622 | SEZ6L2 | 26470 | 20741 | 0.6115 | 0.0000 | |
| GSE53624 | SEZ6L2 | 26470 | 20741 | 0.5247 | 0.0000 | |
| GSE63941 | SEZ6L2 | 26470 | 238406_x_at | 0.3610 | 0.0265 | |
| GSE77861 | SEZ6L2 | 26470 | 238404_x_at | -0.1864 | 0.3342 | |
| GSE97050 | SEZ6L2 | 26470 | A_23_P10194 | 0.3485 | 0.5920 | |
| SRP007169 | SEZ6L2 | 26470 | RNAseq | 5.4575 | 0.0003 | |
| SRP064894 | SEZ6L2 | 26470 | RNAseq | 2.2611 | 0.0001 | |
| SRP133303 | SEZ6L2 | 26470 | RNAseq | 2.0226 | 0.0000 | |
| SRP159526 | SEZ6L2 | 26470 | RNAseq | 2.8355 | 0.0006 | |
| SRP193095 | SEZ6L2 | 26470 | RNAseq | 1.2168 | 0.0074 | |
| SRP219564 | SEZ6L2 | 26470 | RNAseq | 3.7444 | 0.0000 | |
| TCGA | SEZ6L2 | 26470 | RNAseq | -0.1690 | 0.3205 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by SEZ6L2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SEZ6L2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SEZ6L2 | 26470 | 5 | 5 | 20 | |
| GSE20123 | SEZ6L2 | 26470 | 5 | 4 | 21 | |
| GSE43470 | SEZ6L2 | 26470 | 3 | 3 | 37 | |
| GSE46452 | SEZ6L2 | 26470 | 38 | 1 | 20 | |
| GSE47630 | SEZ6L2 | 26470 | 11 | 7 | 22 | |
| GSE54993 | SEZ6L2 | 26470 | 3 | 5 | 62 | |
| GSE54994 | SEZ6L2 | 26470 | 5 | 9 | 39 | |
| GSE60625 | SEZ6L2 | 26470 | 4 | 0 | 7 | |
| GSE74703 | SEZ6L2 | 26470 | 3 | 2 | 31 | |
| GSE74704 | SEZ6L2 | 26470 | 3 | 2 | 15 | |
| TCGA | SEZ6L2 | 26470 | 20 | 11 | 65 |
Total number of gains: 100; Total number of losses: 49; Total Number of normals: 339.
Somatic mutations of SEZ6L2:
Generating mutation plots.
Highly correlated genes for SEZ6L2:
Showing top 20/533 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SEZ6L2 | FAM99B | 0.770838 | 3 | 0 | 3 |
| SEZ6L2 | ABI3 | 0.758017 | 3 | 0 | 3 |
| SEZ6L2 | RIN1 | 0.74667 | 3 | 0 | 3 |
| SEZ6L2 | AIRE | 0.739265 | 3 | 0 | 3 |
| SEZ6L2 | TTC9B | 0.719363 | 4 | 0 | 4 |
| SEZ6L2 | LIF | 0.718819 | 4 | 0 | 4 |
| SEZ6L2 | LRRC46 | 0.711306 | 3 | 0 | 3 |
| SEZ6L2 | OPTC | 0.698177 | 3 | 0 | 3 |
| SEZ6L2 | F2 | 0.69094 | 3 | 0 | 3 |
| SEZ6L2 | RHAG | 0.690328 | 4 | 0 | 4 |
| SEZ6L2 | CSHL1 | 0.68895 | 4 | 0 | 4 |
| SEZ6L2 | LINC00608 | 0.683187 | 4 | 0 | 4 |
| SEZ6L2 | CELF4 | 0.682668 | 4 | 0 | 4 |
| SEZ6L2 | JSRP1 | 0.67728 | 5 | 0 | 4 |
| SEZ6L2 | KCNH4 | 0.67569 | 3 | 0 | 3 |
| SEZ6L2 | PTK2B | 0.675685 | 3 | 0 | 3 |
| SEZ6L2 | PCSK4 | 0.671776 | 3 | 0 | 3 |
| SEZ6L2 | ADAMTS7 | 0.667761 | 5 | 0 | 5 |
| SEZ6L2 | MCEMP1 | 0.664779 | 3 | 0 | 3 |
| SEZ6L2 | SLC25A47 | 0.664164 | 3 | 0 | 3 |
For details and further investigation, click here
