| Full name: solute carrier family 5 member 8 | Alias Symbol: AIT | ||
| Type: protein-coding gene | Cytoband: 12q23.1-q23.2 | ||
| Entrez ID: 160728 | HGNC ID: HGNC:19119 | Ensembl Gene: ENSG00000256870 | OMIM ID: 608044 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC5A8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC5A8 | 160728 | 237503_at | 0.0671 | 0.7593 | |
| GSE26886 | SLC5A8 | 160728 | 237503_at | 0.3365 | 0.0046 | |
| GSE45670 | SLC5A8 | 160728 | 237503_at | 0.0378 | 0.7006 | |
| GSE53622 | SLC5A8 | 160728 | 14840 | -0.3332 | 0.0235 | |
| GSE53624 | SLC5A8 | 160728 | 14840 | -0.5545 | 0.0000 | |
| GSE63941 | SLC5A8 | 160728 | 237503_at | 0.2077 | 0.0873 | |
| GSE77861 | SLC5A8 | 160728 | 237503_at | -0.0819 | 0.3746 | |
| SRP133303 | SLC5A8 | 160728 | RNAseq | -0.8016 | 0.0158 | |
| TCGA | SLC5A8 | 160728 | RNAseq | 0.6857 | 0.5575 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SLC5A8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC5A8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC5A8 | 160728 | 2 | 2 | 26 | |
| GSE20123 | SLC5A8 | 160728 | 2 | 2 | 26 | |
| GSE43470 | SLC5A8 | 160728 | 2 | 0 | 41 | |
| GSE46452 | SLC5A8 | 160728 | 9 | 1 | 49 | |
| GSE47630 | SLC5A8 | 160728 | 9 | 1 | 30 | |
| GSE54993 | SLC5A8 | 160728 | 0 | 5 | 65 | |
| GSE54994 | SLC5A8 | 160728 | 4 | 2 | 47 | |
| GSE60625 | SLC5A8 | 160728 | 0 | 0 | 11 | |
| GSE74703 | SLC5A8 | 160728 | 2 | 0 | 34 | |
| GSE74704 | SLC5A8 | 160728 | 1 | 2 | 17 | |
| TCGA | SLC5A8 | 160728 | 19 | 10 | 67 |
Total number of gains: 50; Total number of losses: 25; Total Number of normals: 413.
Somatic mutations of SLC5A8:
Generating mutation plots.
Highly correlated genes for SLC5A8:
Showing top 20/65 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC5A8 | SNAPC1 | 0.751302 | 3 | 0 | 3 |
| SLC5A8 | C11orf97 | 0.680343 | 3 | 0 | 3 |
| SLC5A8 | NCAN | 0.663212 | 3 | 0 | 3 |
| SLC5A8 | IL37 | 0.66064 | 3 | 0 | 3 |
| SLC5A8 | ADAMTS14 | 0.657177 | 3 | 0 | 3 |
| SLC5A8 | CERCAM | 0.652902 | 3 | 0 | 3 |
| SLC5A8 | TNNT1 | 0.648575 | 3 | 0 | 3 |
| SLC5A8 | CPT1C | 0.645311 | 3 | 0 | 3 |
| SLC5A8 | MAPK11 | 0.642864 | 3 | 0 | 3 |
| SLC5A8 | PAGE1 | 0.639944 | 3 | 0 | 3 |
| SLC5A8 | SEMA6B | 0.623061 | 4 | 0 | 3 |
| SLC5A8 | LHX1 | 0.620798 | 4 | 0 | 3 |
| SLC5A8 | C9orf131 | 0.614824 | 4 | 0 | 3 |
| SLC5A8 | SF3A2 | 0.613869 | 3 | 0 | 3 |
| SLC5A8 | SNX8 | 0.608805 | 3 | 0 | 3 |
| SLC5A8 | GTPBP10 | 0.608656 | 3 | 0 | 3 |
| SLC5A8 | MSI1 | 0.606959 | 4 | 0 | 3 |
| SLC5A8 | C1orf158 | 0.60291 | 3 | 0 | 3 |
| SLC5A8 | AUP1 | 0.602416 | 3 | 0 | 3 |
| SLC5A8 | CDCA4 | 0.590227 | 4 | 0 | 3 |
For details and further investigation, click here
