| Full name: catalase | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11p13 | ||
| Entrez ID: 847 | HGNC ID: HGNC:1516 | Ensembl Gene: ENSG00000121691 | OMIM ID: 115500 |
| Drug and gene relationship at DGIdb | |||
CAT involved pathways:
Expression of CAT:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CAT | 847 | 201432_at | -0.3061 | 0.7080 | |
| GSE20347 | CAT | 847 | 201432_at | -0.3807 | 0.1431 | |
| GSE23400 | CAT | 847 | 201432_at | -0.0129 | 0.9238 | |
| GSE26886 | CAT | 847 | 201432_at | 0.2438 | 0.4344 | |
| GSE29001 | CAT | 847 | 201432_at | -0.4803 | 0.2868 | |
| GSE38129 | CAT | 847 | 201432_at | -0.6543 | 0.0046 | |
| GSE45670 | CAT | 847 | 201432_at | -0.8311 | 0.0025 | |
| GSE53622 | CAT | 847 | 9736 | -0.5670 | 0.0000 | |
| GSE53624 | CAT | 847 | 9736 | -0.5689 | 0.0000 | |
| GSE63941 | CAT | 847 | 201432_at | -0.5400 | 0.2868 | |
| GSE77861 | CAT | 847 | 201432_at | -0.3808 | 0.3706 | |
| GSE97050 | CAT | 847 | A_23_P105138 | -0.4251 | 0.1450 | |
| SRP007169 | CAT | 847 | RNAseq | -1.0927 | 0.0512 | |
| SRP008496 | CAT | 847 | RNAseq | -1.0492 | 0.0006 | |
| SRP064894 | CAT | 847 | RNAseq | -0.5642 | 0.0018 | |
| SRP133303 | CAT | 847 | RNAseq | -0.4838 | 0.0166 | |
| SRP159526 | CAT | 847 | RNAseq | -0.3795 | 0.3606 | |
| SRP193095 | CAT | 847 | RNAseq | -0.6068 | 0.0004 | |
| SRP219564 | CAT | 847 | RNAseq | -0.3775 | 0.3777 | |
| TCGA | CAT | 847 | RNAseq | -0.3441 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CAT expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CAT:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CAT | 847 | 1 | 6 | 23 | |
| GSE20123 | CAT | 847 | 1 | 5 | 24 | |
| GSE43470 | CAT | 847 | 3 | 4 | 36 | |
| GSE46452 | CAT | 847 | 7 | 5 | 47 | |
| GSE47630 | CAT | 847 | 3 | 10 | 27 | |
| GSE54993 | CAT | 847 | 3 | 2 | 65 | |
| GSE54994 | CAT | 847 | 3 | 10 | 40 | |
| GSE60625 | CAT | 847 | 0 | 0 | 11 | |
| GSE74703 | CAT | 847 | 3 | 2 | 31 | |
| GSE74704 | CAT | 847 | 0 | 3 | 17 | |
| TCGA | CAT | 847 | 14 | 23 | 59 |
Total number of gains: 38; Total number of losses: 70; Total Number of normals: 380.
Somatic mutations of CAT:
Generating mutation plots.
Highly correlated genes for CAT:
Showing top 20/699 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CAT | ZNF862 | 0.794402 | 3 | 0 | 3 |
| CAT | STK38L | 0.770755 | 4 | 0 | 4 |
| CAT | HDHD2 | 0.748947 | 3 | 0 | 3 |
| CAT | FOXJ2 | 0.729 | 3 | 0 | 3 |
| CAT | AGBL5 | 0.715067 | 3 | 0 | 3 |
| CAT | UBXN10 | 0.713148 | 3 | 0 | 3 |
| CAT | CYP2U1 | 0.705178 | 5 | 0 | 5 |
| CAT | USP24 | 0.702431 | 3 | 0 | 3 |
| CAT | IGSF11 | 0.699106 | 3 | 0 | 3 |
| CAT | PITHD1 | 0.69887 | 3 | 0 | 3 |
| CAT | CLUAP1 | 0.696036 | 3 | 0 | 3 |
| CAT | EPDR1 | 0.694653 | 4 | 0 | 3 |
| CAT | ZBTB16 | 0.693655 | 5 | 0 | 5 |
| CAT | CCDC159 | 0.693184 | 4 | 0 | 3 |
| CAT | CDO1 | 0.6925 | 5 | 0 | 4 |
| CAT | BCAS3 | 0.692188 | 4 | 0 | 3 |
| CAT | ROGDI | 0.69085 | 4 | 0 | 4 |
| CAT | C10orf82 | 0.689238 | 3 | 0 | 3 |
| CAT | ZNF649 | 0.688514 | 3 | 0 | 3 |
| CAT | SLC35D2 | 0.687123 | 3 | 0 | 3 |
For details and further investigation, click here
