| Full name: immunoglobulin superfamily member 11 | Alias Symbol: BT-IgSF|MGC35227|Igsf13|VSIG3|CT119 | ||
| Type: protein-coding gene | Cytoband: 3q13.32 | ||
| Entrez ID: 152404 | HGNC ID: HGNC:16669 | Ensembl Gene: ENSG00000144847 | OMIM ID: 608351 |
| Drug and gene relationship at DGIdb | |||
Expression of IGSF11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IGSF11 | 152404 | 228375_at | 0.0822 | 0.9646 | |
| GSE26886 | IGSF11 | 152404 | 228375_at | 0.2914 | 0.6428 | |
| GSE45670 | IGSF11 | 152404 | 228375_at | -0.0633 | 0.9294 | |
| GSE53622 | IGSF11 | 152404 | 95014 | 0.4425 | 0.0699 | |
| GSE53624 | IGSF11 | 152404 | 95014 | 0.2780 | 0.1417 | |
| GSE63941 | IGSF11 | 152404 | 228375_at | 1.4099 | 0.0494 | |
| GSE77861 | IGSF11 | 152404 | 228375_at | 0.9140 | 0.1368 | |
| GSE97050 | IGSF11 | 152404 | A_23_P398189 | -0.0617 | 0.9153 | |
| SRP007169 | IGSF11 | 152404 | RNAseq | 1.3671 | 0.1011 | |
| SRP008496 | IGSF11 | 152404 | RNAseq | 1.0588 | 0.0624 | |
| SRP064894 | IGSF11 | 152404 | RNAseq | -0.0758 | 0.8557 | |
| SRP133303 | IGSF11 | 152404 | RNAseq | 0.5845 | 0.1497 | |
| SRP159526 | IGSF11 | 152404 | RNAseq | 1.7786 | 0.0001 | |
| SRP193095 | IGSF11 | 152404 | RNAseq | 0.6267 | 0.0247 | |
| SRP219564 | IGSF11 | 152404 | RNAseq | 0.8043 | 0.3422 | |
| TCGA | IGSF11 | 152404 | RNAseq | 0.3243 | 0.2364 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by IGSF11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IGSF11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IGSF11 | 152404 | 17 | 0 | 13 | |
| GSE20123 | IGSF11 | 152404 | 17 | 0 | 13 | |
| GSE43470 | IGSF11 | 152404 | 21 | 1 | 21 | |
| GSE46452 | IGSF11 | 152404 | 14 | 5 | 40 | |
| GSE47630 | IGSF11 | 152404 | 16 | 5 | 19 | |
| GSE54993 | IGSF11 | 152404 | 2 | 6 | 62 | |
| GSE54994 | IGSF11 | 152404 | 30 | 4 | 19 | |
| GSE60625 | IGSF11 | 152404 | 0 | 6 | 5 | |
| GSE74703 | IGSF11 | 152404 | 17 | 1 | 18 | |
| GSE74704 | IGSF11 | 152404 | 13 | 0 | 7 | |
| TCGA | IGSF11 | 152404 | 53 | 7 | 36 |
Total number of gains: 200; Total number of losses: 35; Total Number of normals: 253.
Somatic mutations of IGSF11:
Generating mutation plots.
Highly correlated genes for IGSF11:
Showing top 20/147 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IGSF11 | PAQR3 | 0.830819 | 3 | 0 | 3 |
| IGSF11 | DZIP3 | 0.747795 | 3 | 0 | 3 |
| IGSF11 | DDIT3 | 0.723488 | 3 | 0 | 3 |
| IGSF11 | GOLPH3 | 0.722715 | 3 | 0 | 3 |
| IGSF11 | WDR35 | 0.718544 | 3 | 0 | 3 |
| IGSF11 | CCNT1 | 0.708205 | 3 | 0 | 3 |
| IGSF11 | PHIP | 0.706918 | 3 | 0 | 3 |
| IGSF11 | ANKRD40 | 0.70416 | 4 | 0 | 4 |
| IGSF11 | CUL1 | 0.700384 | 3 | 0 | 3 |
| IGSF11 | CAT | 0.699106 | 3 | 0 | 3 |
| IGSF11 | KLF11 | 0.696934 | 3 | 0 | 3 |
| IGSF11 | PHOSPHO2 | 0.688723 | 4 | 0 | 3 |
| IGSF11 | ZNF512 | 0.688647 | 3 | 0 | 3 |
| IGSF11 | HSF2 | 0.685614 | 5 | 0 | 3 |
| IGSF11 | DEDD | 0.685226 | 3 | 0 | 3 |
| IGSF11 | PPP6R3 | 0.683893 | 3 | 0 | 3 |
| IGSF11 | ARMCX6 | 0.683206 | 3 | 0 | 3 |
| IGSF11 | ZNF747 | 0.681813 | 3 | 0 | 3 |
| IGSF11 | MCPH1 | 0.677307 | 3 | 0 | 3 |
| IGSF11 | MRPL24 | 0.676066 | 3 | 0 | 3 |
For details and further investigation, click here
