| Full name: zinc finger protein 649 | Alias Symbol: FLJ12644 | ||
| Type: protein-coding gene | Cytoband: 19q13.41 | ||
| Entrez ID: 65251 | HGNC ID: HGNC:25741 | Ensembl Gene: ENSG00000198093 | OMIM ID: 611903 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF649:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF649 | 65251 | 223616_at | -0.2331 | 0.8224 | |
| GSE26886 | ZNF649 | 65251 | 223616_at | -0.2502 | 0.1449 | |
| GSE45670 | ZNF649 | 65251 | 223616_at | -0.2394 | 0.0529 | |
| GSE53622 | ZNF649 | 65251 | 53692 | -0.2907 | 0.1261 | |
| GSE53624 | ZNF649 | 65251 | 53692 | -1.0239 | 0.0000 | |
| GSE63941 | ZNF649 | 65251 | 223616_at | -0.1627 | 0.7981 | |
| GSE77861 | ZNF649 | 65251 | 223616_at | -0.1403 | 0.3288 | |
| GSE97050 | ZNF649 | 65251 | A_23_P208208 | 0.0672 | 0.7369 | |
| SRP007169 | ZNF649 | 65251 | RNAseq | -0.2584 | 0.7048 | |
| SRP064894 | ZNF649 | 65251 | RNAseq | -0.5372 | 0.0263 | |
| SRP133303 | ZNF649 | 65251 | RNAseq | -0.1145 | 0.6601 | |
| SRP159526 | ZNF649 | 65251 | RNAseq | -0.5294 | 0.0824 | |
| SRP193095 | ZNF649 | 65251 | RNAseq | -0.2963 | 0.0456 | |
| SRP219564 | ZNF649 | 65251 | RNAseq | -0.4810 | 0.4196 | |
| TCGA | ZNF649 | 65251 | RNAseq | -0.4604 | 0.0006 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ZNF649 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF649:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF649 | 65251 | 3 | 4 | 23 | |
| GSE20123 | ZNF649 | 65251 | 3 | 3 | 24 | |
| GSE43470 | ZNF649 | 65251 | 2 | 12 | 29 | |
| GSE46452 | ZNF649 | 65251 | 45 | 1 | 13 | |
| GSE47630 | ZNF649 | 65251 | 10 | 6 | 24 | |
| GSE54993 | ZNF649 | 65251 | 17 | 4 | 49 | |
| GSE54994 | ZNF649 | 65251 | 4 | 14 | 35 | |
| GSE60625 | ZNF649 | 65251 | 9 | 0 | 2 | |
| GSE74703 | ZNF649 | 65251 | 2 | 8 | 26 | |
| GSE74704 | ZNF649 | 65251 | 3 | 1 | 16 | |
| TCGA | ZNF649 | 65251 | 14 | 20 | 62 |
Total number of gains: 112; Total number of losses: 73; Total Number of normals: 303.
Somatic mutations of ZNF649:
Generating mutation plots.
Highly correlated genes for ZNF649:
Showing top 20/340 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF649 | LYRM1 | 0.778005 | 3 | 0 | 3 |
| ZNF649 | RABL3 | 0.765483 | 3 | 0 | 3 |
| ZNF649 | CTR9 | 0.760439 | 3 | 0 | 3 |
| ZNF649 | NSA2 | 0.756065 | 3 | 0 | 3 |
| ZNF649 | SLC35B3 | 0.755597 | 3 | 0 | 3 |
| ZNF649 | UBE2R2 | 0.754114 | 3 | 0 | 3 |
| ZNF649 | ABHD16A | 0.751015 | 3 | 0 | 3 |
| ZNF649 | RRAGB | 0.750018 | 3 | 0 | 3 |
| ZNF649 | DPH3 | 0.736668 | 3 | 0 | 3 |
| ZNF649 | BACH1 | 0.735675 | 3 | 0 | 3 |
| ZNF649 | MYSM1 | 0.734004 | 3 | 0 | 3 |
| ZNF649 | TWF1 | 0.727704 | 3 | 0 | 3 |
| ZNF649 | FUCA1 | 0.722152 | 3 | 0 | 3 |
| ZNF649 | ZNF790 | 0.719984 | 3 | 0 | 3 |
| ZNF649 | GCC2 | 0.717267 | 3 | 0 | 3 |
| ZNF649 | CREB1 | 0.715525 | 3 | 0 | 3 |
| ZNF649 | RNF6 | 0.713963 | 3 | 0 | 3 |
| ZNF649 | ATG4A | 0.713719 | 3 | 0 | 3 |
| ZNF649 | UBR2 | 0.713513 | 4 | 0 | 3 |
| ZNF649 | NSMCE4A | 0.710768 | 3 | 0 | 3 |
For details and further investigation, click here
