| Full name: cysteine dioxygenase type 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 5q22.3 | ||
| Entrez ID: 1036 | HGNC ID: HGNC:1795 | Ensembl Gene: ENSG00000129596 | OMIM ID: 603943 |
| Drug and gene relationship at DGIdb | |||
Expression of CDO1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDO1 | 1036 | 204154_at | -1.1953 | 0.2260 | |
| GSE20347 | CDO1 | 1036 | 204154_at | 0.0197 | 0.9412 | |
| GSE23400 | CDO1 | 1036 | 204154_at | -0.2172 | 0.0003 | |
| GSE26886 | CDO1 | 1036 | 243706_at | 0.0581 | 0.6604 | |
| GSE29001 | CDO1 | 1036 | 204154_at | 0.1416 | 0.7649 | |
| GSE38129 | CDO1 | 1036 | 204154_at | -0.8331 | 0.0528 | |
| GSE45670 | CDO1 | 1036 | 204154_at | -1.8686 | 0.0092 | |
| GSE53622 | CDO1 | 1036 | 125822 | -1.2108 | 0.0000 | |
| GSE53624 | CDO1 | 1036 | 125822 | -1.2385 | 0.0000 | |
| GSE63941 | CDO1 | 1036 | 243706_at | -0.2586 | 0.1342 | |
| GSE77861 | CDO1 | 1036 | 243706_at | -0.0027 | 0.9799 | |
| GSE97050 | CDO1 | 1036 | A_23_P30294 | -0.3992 | 0.3145 | |
| SRP064894 | CDO1 | 1036 | RNAseq | -1.4043 | 0.0028 | |
| SRP133303 | CDO1 | 1036 | RNAseq | -1.3480 | 0.0125 | |
| SRP219564 | CDO1 | 1036 | RNAseq | -0.9623 | 0.3711 | |
| TCGA | CDO1 | 1036 | RNAseq | -0.9969 | 0.0319 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by CDO1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDO1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDO1 | 1036 | 1 | 13 | 16 | |
| GSE20123 | CDO1 | 1036 | 1 | 13 | 16 | |
| GSE43470 | CDO1 | 1036 | 3 | 8 | 32 | |
| GSE46452 | CDO1 | 1036 | 0 | 28 | 31 | |
| GSE47630 | CDO1 | 1036 | 0 | 21 | 19 | |
| GSE54993 | CDO1 | 1036 | 9 | 1 | 60 | |
| GSE54994 | CDO1 | 1036 | 1 | 15 | 37 | |
| GSE60625 | CDO1 | 1036 | 0 | 0 | 11 | |
| GSE74703 | CDO1 | 1036 | 2 | 6 | 28 | |
| GSE74704 | CDO1 | 1036 | 1 | 7 | 12 | |
| TCGA | CDO1 | 1036 | 2 | 41 | 53 |
Total number of gains: 20; Total number of losses: 153; Total Number of normals: 315.
Somatic mutations of CDO1:
Generating mutation plots.
Highly correlated genes for CDO1:
Showing top 20/910 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDO1 | GDF10 | 0.767665 | 3 | 0 | 3 |
| CDO1 | COMMD6 | 0.743219 | 3 | 0 | 3 |
| CDO1 | C1QTNF7 | 0.729587 | 5 | 0 | 5 |
| CDO1 | LRFN5 | 0.729095 | 4 | 0 | 4 |
| CDO1 | RNASE4 | 0.726553 | 6 | 0 | 5 |
| CDO1 | PDE1A | 0.724667 | 7 | 0 | 7 |
| CDO1 | SLIT2 | 0.724106 | 7 | 0 | 7 |
| CDO1 | P2RY12 | 0.717311 | 5 | 0 | 5 |
| CDO1 | MEOX2 | 0.715391 | 7 | 0 | 7 |
| CDO1 | FIBIN | 0.715119 | 4 | 0 | 3 |
| CDO1 | TCEAL6 | 0.712599 | 3 | 0 | 3 |
| CDO1 | TNFSF12 | 0.712466 | 3 | 0 | 3 |
| CDO1 | FAM98C | 0.71172 | 3 | 0 | 3 |
| CDO1 | MYADM | 0.707911 | 3 | 0 | 3 |
| CDO1 | MFF | 0.70579 | 3 | 0 | 3 |
| CDO1 | PLEKHB1 | 0.704369 | 7 | 0 | 7 |
| CDO1 | CNTLN | 0.704093 | 3 | 0 | 3 |
| CDO1 | RAB9B | 0.702378 | 5 | 0 | 5 |
| CDO1 | BCL2 | 0.701341 | 4 | 0 | 3 |
| CDO1 | BEND5 | 0.69538 | 8 | 0 | 7 |
For details and further investigation, click here
