| Full name: coiled-coil domain containing 60 | Alias Symbol: MGC39827 | ||
| Type: protein-coding gene | Cytoband: 12q24.23 | ||
| Entrez ID: 160777 | HGNC ID: HGNC:28610 | Ensembl Gene: ENSG00000183273 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC60:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC60 | 160777 | 1554117_at | -0.1206 | 0.6603 | |
| GSE26886 | CCDC60 | 160777 | 1554117_at | 0.1660 | 0.2375 | |
| GSE45670 | CCDC60 | 160777 | 1554117_at | 0.1453 | 0.0864 | |
| GSE53622 | CCDC60 | 160777 | 20460 | -0.4477 | 0.0132 | |
| GSE53624 | CCDC60 | 160777 | 20460 | -1.4318 | 0.0000 | |
| GSE63941 | CCDC60 | 160777 | 1554117_at | 0.1646 | 0.4088 | |
| GSE77861 | CCDC60 | 160777 | 1554117_at | -0.0460 | 0.6729 | |
| SRP133303 | CCDC60 | 160777 | RNAseq | -1.6436 | 0.0001 | |
| SRP159526 | CCDC60 | 160777 | RNAseq | -2.3823 | 0.0244 | |
| TCGA | CCDC60 | 160777 | RNAseq | 0.0932 | 0.9285 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by CCDC60 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC60:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC60 | 160777 | 6 | 2 | 22 | |
| GSE20123 | CCDC60 | 160777 | 6 | 2 | 22 | |
| GSE43470 | CCDC60 | 160777 | 2 | 2 | 39 | |
| GSE46452 | CCDC60 | 160777 | 9 | 1 | 49 | |
| GSE47630 | CCDC60 | 160777 | 9 | 3 | 28 | |
| GSE54993 | CCDC60 | 160777 | 0 | 5 | 65 | |
| GSE54994 | CCDC60 | 160777 | 6 | 6 | 41 | |
| GSE60625 | CCDC60 | 160777 | 0 | 0 | 11 | |
| GSE74703 | CCDC60 | 160777 | 2 | 1 | 33 | |
| GSE74704 | CCDC60 | 160777 | 3 | 2 | 15 | |
| TCGA | CCDC60 | 160777 | 22 | 11 | 63 |
Total number of gains: 65; Total number of losses: 35; Total Number of normals: 388.
Somatic mutations of CCDC60:
Generating mutation plots.
Highly correlated genes for CCDC60:
Showing top 20/71 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC60 | CKM | 0.669696 | 3 | 0 | 3 |
| CCDC60 | B4GALNT2 | 0.66372 | 3 | 0 | 3 |
| CCDC60 | NOS1 | 0.654315 | 3 | 0 | 3 |
| CCDC60 | NUTM1 | 0.651323 | 3 | 0 | 3 |
| CCDC60 | KLHL30-AS1 | 0.650555 | 3 | 0 | 3 |
| CCDC60 | FBXL18 | 0.641784 | 3 | 0 | 3 |
| CCDC60 | KIR2DS1 | 0.638371 | 3 | 0 | 3 |
| CCDC60 | TNFRSF13C | 0.632232 | 4 | 0 | 3 |
| CCDC60 | TEX13B | 0.627243 | 4 | 0 | 4 |
| CCDC60 | LINC00928 | 0.622259 | 3 | 0 | 3 |
| CCDC60 | BEST3 | 0.621625 | 3 | 0 | 3 |
| CCDC60 | SLC25A35 | 0.618241 | 3 | 0 | 3 |
| CCDC60 | ZNF582-AS1 | 0.614433 | 3 | 0 | 3 |
| CCDC60 | C10orf71-AS1 | 0.613548 | 3 | 0 | 3 |
| CCDC60 | LCNL1 | 0.613439 | 3 | 0 | 3 |
| CCDC60 | WFIKKN1 | 0.611978 | 4 | 0 | 3 |
| CCDC60 | TAC3 | 0.60836 | 3 | 0 | 3 |
| CCDC60 | DGKK | 0.602985 | 3 | 0 | 3 |
| CCDC60 | RBP5 | 0.59848 | 4 | 0 | 3 |
| CCDC60 | CD300LB | 0.597212 | 3 | 0 | 3 |
For details and further investigation, click here
