| Full name: cytochrome c oxidase subunit 6B1 | Alias Symbol: COXG | ||
| Type: protein-coding gene | Cytoband: 19q13.12 | ||
| Entrez ID: 1340 | HGNC ID: HGNC:2280 | Ensembl Gene: ENSG00000126267 | OMIM ID: 124089 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of COX6B1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COX6B1 | 1340 | 201441_at | -0.2317 | 0.2312 | |
| GSE20347 | COX6B1 | 1340 | 201441_at | -0.4736 | 0.0033 | |
| GSE23400 | COX6B1 | 1340 | 201441_at | -0.3131 | 0.0008 | |
| GSE26886 | COX6B1 | 1340 | 201441_at | -0.3622 | 0.0646 | |
| GSE29001 | COX6B1 | 1340 | 201441_at | -0.6154 | 0.0251 | |
| GSE38129 | COX6B1 | 1340 | 201441_at | -0.2676 | 0.0525 | |
| GSE45670 | COX6B1 | 1340 | 201441_at | -0.1315 | 0.3901 | |
| GSE53622 | COX6B1 | 1340 | 20778 | -0.7028 | 0.0000 | |
| GSE53624 | COX6B1 | 1340 | 20778 | -0.3852 | 0.0000 | |
| GSE63941 | COX6B1 | 1340 | 201441_at | 0.7321 | 0.0948 | |
| GSE77861 | COX6B1 | 1340 | 201441_at | -0.2655 | 0.2573 | |
| GSE97050 | COX6B1 | 1340 | A_23_P108244 | -0.5657 | 0.1057 | |
| SRP007169 | COX6B1 | 1340 | RNAseq | -0.3984 | 0.5304 | |
| SRP008496 | COX6B1 | 1340 | RNAseq | -1.4460 | 0.0000 | |
| SRP064894 | COX6B1 | 1340 | RNAseq | 0.0203 | 0.9560 | |
| SRP133303 | COX6B1 | 1340 | RNAseq | -0.3676 | 0.1340 | |
| SRP159526 | COX6B1 | 1340 | RNAseq | -0.0607 | 0.8408 | |
| SRP193095 | COX6B1 | 1340 | RNAseq | -0.8390 | 0.0000 | |
| SRP219564 | COX6B1 | 1340 | RNAseq | -0.5664 | 0.0219 | |
| TCGA | COX6B1 | 1340 | RNAseq | -0.0290 | 0.6203 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by COX6B1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COX6B1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COX6B1 | 1340 | 6 | 4 | 20 | |
| GSE20123 | COX6B1 | 1340 | 6 | 3 | 21 | |
| GSE43470 | COX6B1 | 1340 | 3 | 7 | 33 | |
| GSE46452 | COX6B1 | 1340 | 48 | 1 | 10 | |
| GSE47630 | COX6B1 | 1340 | 9 | 5 | 26 | |
| GSE54993 | COX6B1 | 1340 | 17 | 3 | 50 | |
| GSE54994 | COX6B1 | 1340 | 7 | 9 | 37 | |
| GSE60625 | COX6B1 | 1340 | 9 | 0 | 2 | |
| GSE74703 | COX6B1 | 1340 | 3 | 4 | 29 | |
| GSE74704 | COX6B1 | 1340 | 6 | 1 | 13 | |
| TCGA | COX6B1 | 1340 | 22 | 10 | 64 |
Total number of gains: 136; Total number of losses: 47; Total Number of normals: 305.
Somatic mutations of COX6B1:
Generating mutation plots.
Highly correlated genes for COX6B1:
Showing top 20/755 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COX6B1 | ARGLU1 | 0.827796 | 3 | 0 | 3 |
| COX6B1 | ZNF44 | 0.750736 | 3 | 0 | 3 |
| COX6B1 | SLTM | 0.746059 | 3 | 0 | 3 |
| COX6B1 | RPL19 | 0.743689 | 3 | 0 | 3 |
| COX6B1 | COMTD1 | 0.739348 | 4 | 0 | 4 |
| COX6B1 | ZNF33B | 0.7281 | 3 | 0 | 3 |
| COX6B1 | EEF2 | 0.723969 | 3 | 0 | 3 |
| COX6B1 | ZNF83 | 0.722162 | 3 | 0 | 3 |
| COX6B1 | COMMD9 | 0.721837 | 3 | 0 | 3 |
| COX6B1 | POLR2I | 0.718797 | 12 | 0 | 11 |
| COX6B1 | ZNF528 | 0.716298 | 3 | 0 | 3 |
| COX6B1 | ACVR2A | 0.713684 | 3 | 0 | 3 |
| COX6B1 | PAN3 | 0.708827 | 3 | 0 | 3 |
| COX6B1 | PRMT6 | 0.70299 | 3 | 0 | 3 |
| COX6B1 | ARF1 | 0.697501 | 3 | 0 | 3 |
| COX6B1 | RNF181 | 0.696777 | 3 | 0 | 3 |
| COX6B1 | EIF3K | 0.688521 | 12 | 0 | 10 |
| COX6B1 | TBCA | 0.687951 | 3 | 0 | 3 |
| COX6B1 | ZNF91 | 0.686709 | 4 | 0 | 3 |
| COX6B1 | TMEM147 | 0.6862 | 13 | 0 | 12 |
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