| Full name: tubulin folding cofactor A | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 5q14.1 | ||
| Entrez ID: 6902 | HGNC ID: HGNC:11579 | Ensembl Gene: ENSG00000171530 | OMIM ID: 610058 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TBCA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TBCA | 6902 | 203667_at | -0.3042 | 0.5784 | |
| GSE20347 | TBCA | 6902 | 203667_at | -0.1997 | 0.1084 | |
| GSE23400 | TBCA | 6902 | 203667_at | -0.0071 | 0.9397 | |
| GSE26886 | TBCA | 6902 | 203667_at | 0.2915 | 0.0821 | |
| GSE29001 | TBCA | 6902 | 203667_at | -0.0213 | 0.9074 | |
| GSE38129 | TBCA | 6902 | 203667_at | -0.0066 | 0.9576 | |
| GSE45670 | TBCA | 6902 | 203667_at | -0.0132 | 0.9201 | |
| GSE53622 | TBCA | 6902 | 36035 | -0.4774 | 0.0000 | |
| GSE53624 | TBCA | 6902 | 36035 | -0.1318 | 0.1130 | |
| GSE63941 | TBCA | 6902 | 203667_at | -0.1271 | 0.6621 | |
| GSE77861 | TBCA | 6902 | 203667_at | -0.0712 | 0.6774 | |
| GSE97050 | TBCA | 6902 | A_33_P3264121 | -0.3343 | 0.2275 | |
| SRP007169 | TBCA | 6902 | RNAseq | 0.7369 | 0.2514 | |
| SRP064894 | TBCA | 6902 | RNAseq | -0.2583 | 0.2445 | |
| SRP133303 | TBCA | 6902 | RNAseq | 0.1594 | 0.4071 | |
| SRP159526 | TBCA | 6902 | RNAseq | -0.2341 | 0.4344 | |
| SRP193095 | TBCA | 6902 | RNAseq | -0.5469 | 0.0000 | |
| SRP219564 | TBCA | 6902 | RNAseq | -0.4993 | 0.0887 | |
| TCGA | TBCA | 6902 | RNAseq | 0.0090 | 0.8639 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TBCA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TBCA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TBCA | 6902 | 1 | 13 | 16 | |
| GSE20123 | TBCA | 6902 | 1 | 13 | 16 | |
| GSE43470 | TBCA | 6902 | 1 | 13 | 29 | |
| GSE46452 | TBCA | 6902 | 0 | 28 | 31 | |
| GSE47630 | TBCA | 6902 | 1 | 19 | 20 | |
| GSE54993 | TBCA | 6902 | 8 | 1 | 61 | |
| GSE54994 | TBCA | 6902 | 1 | 19 | 33 | |
| GSE60625 | TBCA | 6902 | 0 | 0 | 11 | |
| GSE74703 | TBCA | 6902 | 1 | 9 | 26 | |
| GSE74704 | TBCA | 6902 | 1 | 6 | 13 | |
| TCGA | TBCA | 6902 | 5 | 49 | 42 |
Total number of gains: 20; Total number of losses: 170; Total Number of normals: 298.
Somatic mutations of TBCA:
Generating mutation plots.
Highly correlated genes for TBCA:
Showing top 20/397 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TBCA | ANAPC4 | 0.814455 | 3 | 0 | 3 |
| TBCA | AK3 | 0.798496 | 3 | 0 | 3 |
| TBCA | OSBPL2 | 0.747168 | 3 | 0 | 3 |
| TBCA | CEP44 | 0.74575 | 3 | 0 | 3 |
| TBCA | ZSWIM6 | 0.738022 | 4 | 0 | 4 |
| TBCA | HMGN3 | 0.734166 | 3 | 0 | 3 |
| TBCA | ZNF700 | 0.73095 | 3 | 0 | 3 |
| TBCA | PDZD11 | 0.729152 | 4 | 0 | 4 |
| TBCA | OAT | 0.72442 | 3 | 0 | 3 |
| TBCA | RASSF3 | 0.715745 | 3 | 0 | 3 |
| TBCA | FBXO8 | 0.714812 | 3 | 0 | 3 |
| TBCA | HIPK3 | 0.708998 | 4 | 0 | 4 |
| TBCA | APPL1 | 0.708203 | 3 | 0 | 3 |
| TBCA | SSBP1 | 0.707022 | 3 | 0 | 3 |
| TBCA | UFM1 | 0.699455 | 3 | 0 | 3 |
| TBCA | JOSD2 | 0.699405 | 3 | 0 | 3 |
| TBCA | ZNF638 | 0.692719 | 4 | 0 | 4 |
| TBCA | MKNK2 | 0.692665 | 3 | 0 | 3 |
| TBCA | RPL19 | 0.691464 | 3 | 0 | 3 |
| TBCA | COX6B1 | 0.687951 | 3 | 0 | 3 |
For details and further investigation, click here
