| Full name: protein arginine methyltransferase 6 | Alias Symbol: FLJ10559 | ||
| Type: protein-coding gene | Cytoband: 1p13.3 | ||
| Entrez ID: 55170 | HGNC ID: HGNC:18241 | Ensembl Gene: ENSG00000198890 | OMIM ID: 608274 |
| Drug and gene relationship at DGIdb | |||
Expression of PRMT6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRMT6 | 55170 | 223275_at | 0.3240 | 0.7235 | |
| GSE26886 | PRMT6 | 55170 | 223275_at | -0.8453 | 0.0460 | |
| GSE45670 | PRMT6 | 55170 | 223275_at | 0.2364 | 0.3215 | |
| GSE53622 | PRMT6 | 55170 | 54053 | 0.1073 | 0.3749 | |
| GSE53624 | PRMT6 | 55170 | 54053 | 0.0983 | 0.3864 | |
| GSE63941 | PRMT6 | 55170 | 223275_at | -0.3723 | 0.7498 | |
| GSE77861 | PRMT6 | 55170 | 223275_at | -0.2409 | 0.4833 | |
| GSE97050 | PRMT6 | 55170 | A_23_P12336 | 0.3474 | 0.1883 | |
| SRP007169 | PRMT6 | 55170 | RNAseq | 0.8665 | 0.1139 | |
| SRP008496 | PRMT6 | 55170 | RNAseq | 0.7955 | 0.0459 | |
| SRP064894 | PRMT6 | 55170 | RNAseq | -0.0102 | 0.9659 | |
| SRP133303 | PRMT6 | 55170 | RNAseq | 0.2290 | 0.2453 | |
| SRP159526 | PRMT6 | 55170 | RNAseq | 0.0542 | 0.8825 | |
| SRP193095 | PRMT6 | 55170 | RNAseq | -0.0708 | 0.6111 | |
| SRP219564 | PRMT6 | 55170 | RNAseq | -0.1360 | 0.7502 | |
| TCGA | PRMT6 | 55170 | RNAseq | 0.0297 | 0.6888 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PRMT6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRMT6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRMT6 | 55170 | 0 | 11 | 19 | |
| GSE20123 | PRMT6 | 55170 | 0 | 11 | 19 | |
| GSE43470 | PRMT6 | 55170 | 0 | 7 | 36 | |
| GSE46452 | PRMT6 | 55170 | 2 | 2 | 55 | |
| GSE47630 | PRMT6 | 55170 | 9 | 5 | 26 | |
| GSE54993 | PRMT6 | 55170 | 0 | 1 | 69 | |
| GSE54994 | PRMT6 | 55170 | 7 | 4 | 42 | |
| GSE60625 | PRMT6 | 55170 | 0 | 0 | 11 | |
| GSE74703 | PRMT6 | 55170 | 0 | 6 | 30 | |
| GSE74704 | PRMT6 | 55170 | 0 | 7 | 13 | |
| TCGA | PRMT6 | 55170 | 8 | 26 | 62 |
Total number of gains: 26; Total number of losses: 80; Total Number of normals: 382.
Somatic mutations of PRMT6:
Generating mutation plots.
Highly correlated genes for PRMT6:
Showing top 20/306 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRMT6 | C2CD2 | 0.833146 | 3 | 0 | 3 |
| PRMT6 | ARPC1A | 0.786681 | 3 | 0 | 3 |
| PRMT6 | ERI2 | 0.775867 | 3 | 0 | 3 |
| PRMT6 | PEMT | 0.76934 | 3 | 0 | 3 |
| PRMT6 | USP38 | 0.766845 | 3 | 0 | 3 |
| PRMT6 | ZMPSTE24 | 0.765719 | 3 | 0 | 3 |
| PRMT6 | DEXI | 0.762138 | 3 | 0 | 3 |
| PRMT6 | ELAVL1 | 0.755115 | 3 | 0 | 3 |
| PRMT6 | FRS2 | 0.754405 | 3 | 0 | 3 |
| PRMT6 | SCAMP2 | 0.748052 | 3 | 0 | 3 |
| PRMT6 | LAMTOR1 | 0.744939 | 3 | 0 | 3 |
| PRMT6 | PRPF38A | 0.73978 | 3 | 0 | 3 |
| PRMT6 | COPZ1 | 0.732436 | 3 | 0 | 3 |
| PRMT6 | NFXL1 | 0.732281 | 3 | 0 | 3 |
| PRMT6 | FGFR1OP2 | 0.727076 | 3 | 0 | 3 |
| PRMT6 | OXNAD1 | 0.723563 | 3 | 0 | 3 |
| PRMT6 | AQR | 0.720776 | 3 | 0 | 3 |
| PRMT6 | NECAP1 | 0.719513 | 3 | 0 | 3 |
| PRMT6 | ATXN7L3B | 0.716477 | 3 | 0 | 3 |
| PRMT6 | ERI3 | 0.716047 | 3 | 0 | 3 |
For details and further investigation, click here
