| Full name: poly(A) specific ribonuclease subunit PAN3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 13q12.2 | ||
| Entrez ID: 255967 | HGNC ID: HGNC:29991 | Ensembl Gene: ENSG00000152520 | OMIM ID: 617448 |
| Drug and gene relationship at DGIdb | |||
Expression of PAN3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PAN3 | 255967 | 225563_at | -0.1447 | 0.7304 | |
| GSE26886 | PAN3 | 255967 | 225563_at | 0.0630 | 0.8395 | |
| GSE45670 | PAN3 | 255967 | 225563_at | -0.2871 | 0.0406 | |
| GSE53622 | PAN3 | 255967 | 3878 | -0.4851 | 0.0000 | |
| GSE53624 | PAN3 | 255967 | 34345 | -0.3358 | 0.0000 | |
| GSE63941 | PAN3 | 255967 | 225563_at | 0.3133 | 0.3736 | |
| GSE77861 | PAN3 | 255967 | 225563_at | -0.1441 | 0.5898 | |
| GSE97050 | PAN3 | 255967 | A_33_P3259403 | -0.2997 | 0.4259 | |
| SRP007169 | PAN3 | 255967 | RNAseq | -0.4942 | 0.1998 | |
| SRP008496 | PAN3 | 255967 | RNAseq | -0.3336 | 0.0885 | |
| SRP064894 | PAN3 | 255967 | RNAseq | -0.2678 | 0.2486 | |
| SRP133303 | PAN3 | 255967 | RNAseq | -0.2567 | 0.1046 | |
| SRP159526 | PAN3 | 255967 | RNAseq | -0.7793 | 0.0001 | |
| SRP193095 | PAN3 | 255967 | RNAseq | -0.2906 | 0.0110 | |
| SRP219564 | PAN3 | 255967 | RNAseq | -0.5713 | 0.0658 | |
| TCGA | PAN3 | 255967 | RNAseq | -0.0825 | 0.0922 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PAN3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PAN3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PAN3 | 255967 | 1 | 13 | 16 | |
| GSE20123 | PAN3 | 255967 | 1 | 12 | 17 | |
| GSE43470 | PAN3 | 255967 | 2 | 12 | 29 | |
| GSE46452 | PAN3 | 255967 | 0 | 33 | 26 | |
| GSE47630 | PAN3 | 255967 | 3 | 26 | 11 | |
| GSE54993 | PAN3 | 255967 | 11 | 2 | 57 | |
| GSE54994 | PAN3 | 255967 | 2 | 13 | 38 | |
| GSE60625 | PAN3 | 255967 | 0 | 3 | 8 | |
| GSE74703 | PAN3 | 255967 | 2 | 9 | 25 | |
| GSE74704 | PAN3 | 255967 | 0 | 10 | 10 | |
| TCGA | PAN3 | 255967 | 8 | 38 | 50 |
Total number of gains: 30; Total number of losses: 171; Total Number of normals: 287.
Somatic mutations of PAN3:
Generating mutation plots.
Highly correlated genes for PAN3:
Showing top 20/344 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PAN3 | LCOR | 0.793005 | 3 | 0 | 3 |
| PAN3 | ZNF223 | 0.788725 | 3 | 0 | 3 |
| PAN3 | ZNF432 | 0.773941 | 3 | 0 | 3 |
| PAN3 | ZNF227 | 0.770271 | 3 | 0 | 3 |
| PAN3 | ZNF766 | 0.757868 | 3 | 0 | 3 |
| PAN3 | MRPL20 | 0.747553 | 3 | 0 | 3 |
| PAN3 | ZNF800 | 0.745631 | 3 | 0 | 3 |
| PAN3 | DCP1B | 0.741755 | 3 | 0 | 3 |
| PAN3 | PEX14 | 0.739888 | 3 | 0 | 3 |
| PAN3 | GPRC5B | 0.732766 | 3 | 0 | 3 |
| PAN3 | COIL | 0.729535 | 3 | 0 | 3 |
| PAN3 | KDM4B | 0.72905 | 3 | 0 | 3 |
| PAN3 | ZFYVE26 | 0.728153 | 3 | 0 | 3 |
| PAN3 | ZNF506 | 0.725357 | 3 | 0 | 3 |
| PAN3 | BCLAF1 | 0.724984 | 4 | 0 | 4 |
| PAN3 | ZNF93 | 0.724012 | 3 | 0 | 3 |
| PAN3 | FBXL4 | 0.714799 | 3 | 0 | 3 |
| PAN3 | ZNF140 | 0.713223 | 3 | 0 | 3 |
| PAN3 | SUGP2 | 0.712664 | 3 | 0 | 3 |
| PAN3 | COX6B1 | 0.708827 | 3 | 0 | 3 |
For details and further investigation, click here
