| Full name: ring finger protein 181 | Alias Symbol: HSPC238 | ||
| Type: protein-coding gene | Cytoband: 2p11.2 | ||
| Entrez ID: 51255 | HGNC ID: HGNC:28037 | Ensembl Gene: ENSG00000168894 | OMIM ID: 612490 |
| Drug and gene relationship at DGIdb | |||
Expression of RNF181:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNF181 | 51255 | 223064_at | -0.0744 | 0.8228 | |
| GSE26886 | RNF181 | 51255 | 223064_at | 0.0558 | 0.7513 | |
| GSE45670 | RNF181 | 51255 | 223064_at | 0.1661 | 0.3004 | |
| GSE53622 | RNF181 | 51255 | 27550 | 0.1106 | 0.0547 | |
| GSE53624 | RNF181 | 51255 | 27550 | 0.1645 | 0.0004 | |
| GSE63941 | RNF181 | 51255 | 223064_at | 0.6241 | 0.0530 | |
| GSE77861 | RNF181 | 51255 | 223064_at | 0.0773 | 0.7049 | |
| GSE97050 | RNF181 | 51255 | A_23_P108708 | 0.1689 | 0.4236 | |
| SRP007169 | RNF181 | 51255 | RNAseq | -0.9112 | 0.0237 | |
| SRP008496 | RNF181 | 51255 | RNAseq | -0.7159 | 0.0016 | |
| SRP064894 | RNF181 | 51255 | RNAseq | 0.3431 | 0.3159 | |
| SRP133303 | RNF181 | 51255 | RNAseq | 0.2007 | 0.0857 | |
| SRP159526 | RNF181 | 51255 | RNAseq | 0.1231 | 0.5386 | |
| SRP193095 | RNF181 | 51255 | RNAseq | -0.4444 | 0.0012 | |
| SRP219564 | RNF181 | 51255 | RNAseq | -0.0543 | 0.8756 | |
| TCGA | RNF181 | 51255 | RNAseq | 0.0901 | 0.1151 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RNF181 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNF181:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNF181 | 51255 | 9 | 2 | 19 | |
| GSE20123 | RNF181 | 51255 | 9 | 2 | 19 | |
| GSE43470 | RNF181 | 51255 | 6 | 2 | 35 | |
| GSE46452 | RNF181 | 51255 | 2 | 3 | 54 | |
| GSE47630 | RNF181 | 51255 | 7 | 0 | 33 | |
| GSE54993 | RNF181 | 51255 | 0 | 6 | 64 | |
| GSE54994 | RNF181 | 51255 | 10 | 0 | 43 | |
| GSE60625 | RNF181 | 51255 | 0 | 3 | 8 | |
| GSE74703 | RNF181 | 51255 | 5 | 1 | 30 | |
| GSE74704 | RNF181 | 51255 | 7 | 0 | 13 | |
| TCGA | RNF181 | 51255 | 35 | 3 | 58 |
Total number of gains: 90; Total number of losses: 22; Total Number of normals: 376.
Somatic mutations of RNF181:
Generating mutation plots.
Highly correlated genes for RNF181:
Showing top 20/223 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNF181 | LGALSL | 0.79271 | 3 | 0 | 3 |
| RNF181 | AGBL5 | 0.773407 | 3 | 0 | 3 |
| RNF181 | MRPL35 | 0.77025 | 5 | 0 | 5 |
| RNF181 | AP2M1 | 0.747036 | 3 | 0 | 3 |
| RNF181 | EIF3I | 0.734591 | 4 | 0 | 4 |
| RNF181 | RAC1 | 0.729481 | 3 | 0 | 3 |
| RNF181 | PPP6R3 | 0.727448 | 3 | 0 | 3 |
| RNF181 | PTCD3 | 0.725437 | 3 | 0 | 3 |
| RNF181 | MTA3 | 0.724289 | 3 | 0 | 3 |
| RNF181 | ABCB6 | 0.724211 | 3 | 0 | 3 |
| RNF181 | XPO1 | 0.72296 | 3 | 0 | 3 |
| RNF181 | PSMA2 | 0.718919 | 3 | 0 | 3 |
| RNF181 | ADAT1 | 0.708643 | 3 | 0 | 3 |
| RNF181 | NMNAT2 | 0.703765 | 3 | 0 | 3 |
| RNF181 | GAPDH | 0.703544 | 4 | 0 | 4 |
| RNF181 | CD2BP2 | 0.700689 | 5 | 0 | 5 |
| RNF181 | COX6B1 | 0.696777 | 3 | 0 | 3 |
| RNF181 | SLC25A24 | 0.696768 | 3 | 0 | 3 |
| RNF181 | MRPS11 | 0.694862 | 5 | 0 | 5 |
| RNF181 | LRBA | 0.691983 | 3 | 0 | 3 |
For details and further investigation, click here
