| Full name: DEAD-box helicase 43 | Alias Symbol: HAGE|DKFZp434H2114|CT13 | ||
| Type: protein-coding gene | Cytoband: 6q13 | ||
| Entrez ID: 55510 | HGNC ID: HGNC:18677 | Ensembl Gene: ENSG00000080007 | OMIM ID: 606286 |
| Drug and gene relationship at DGIdb | |||
Expression of DDX43:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DDX43 | 55510 | 220004_at | -0.6099 | 0.7034 | |
| GSE20347 | DDX43 | 55510 | 220004_at | 0.0972 | 0.4913 | |
| GSE23400 | DDX43 | 55510 | 220004_at | 0.0564 | 0.2074 | |
| GSE26886 | DDX43 | 55510 | 220004_at | 0.7653 | 0.0635 | |
| GSE29001 | DDX43 | 55510 | 220004_at | 0.1190 | 0.7793 | |
| GSE38129 | DDX43 | 55510 | 220004_at | 0.0426 | 0.7936 | |
| GSE45670 | DDX43 | 55510 | 220004_at | -0.3649 | 0.4316 | |
| GSE53622 | DDX43 | 55510 | 15815 | -0.3614 | 0.1664 | |
| GSE53624 | DDX43 | 55510 | 15815 | -0.2634 | 0.3040 | |
| GSE63941 | DDX43 | 55510 | 220004_at | 0.1692 | 0.9027 | |
| GSE77861 | DDX43 | 55510 | 220004_at | 0.1086 | 0.6833 | |
| GSE97050 | DDX43 | 55510 | A_23_P156445 | -0.0271 | 0.9193 | |
| SRP133303 | DDX43 | 55510 | RNAseq | 0.5855 | 0.2447 | |
| SRP159526 | DDX43 | 55510 | RNAseq | 0.3485 | 0.7267 | |
| SRP219564 | DDX43 | 55510 | RNAseq | -0.4784 | 0.5960 | |
| TCGA | DDX43 | 55510 | RNAseq | 0.0619 | 0.9211 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DDX43 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DDX43:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DDX43 | 55510 | 1 | 3 | 26 | |
| GSE20123 | DDX43 | 55510 | 1 | 2 | 27 | |
| GSE43470 | DDX43 | 55510 | 3 | 0 | 40 | |
| GSE46452 | DDX43 | 55510 | 2 | 11 | 46 | |
| GSE47630 | DDX43 | 55510 | 8 | 4 | 28 | |
| GSE54993 | DDX43 | 55510 | 3 | 2 | 65 | |
| GSE54994 | DDX43 | 55510 | 8 | 9 | 36 | |
| GSE60625 | DDX43 | 55510 | 0 | 1 | 10 | |
| GSE74703 | DDX43 | 55510 | 3 | 0 | 33 | |
| GSE74704 | DDX43 | 55510 | 0 | 1 | 19 | |
| TCGA | DDX43 | 55510 | 10 | 21 | 65 |
Total number of gains: 39; Total number of losses: 54; Total Number of normals: 395.
Somatic mutations of DDX43:
Generating mutation plots.
Highly correlated genes for DDX43:
Showing top 20/24 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DDX43 | RNF215 | 0.669259 | 3 | 0 | 3 |
| DDX43 | MID1 | 0.667329 | 3 | 0 | 3 |
| DDX43 | PAXIP1-AS1 | 0.647933 | 3 | 0 | 3 |
| DDX43 | TKTL1 | 0.635083 | 3 | 0 | 3 |
| DDX43 | USP27X | 0.620307 | 4 | 0 | 3 |
| DDX43 | DACH1 | 0.608953 | 3 | 0 | 3 |
| DDX43 | HPR | 0.608701 | 4 | 0 | 3 |
| DDX43 | OOEP | 0.601537 | 8 | 0 | 6 |
| DDX43 | NRXN1 | 0.597033 | 3 | 0 | 3 |
| DDX43 | UPK1B | 0.592613 | 4 | 0 | 3 |
| DDX43 | ZNF777 | 0.591664 | 3 | 0 | 3 |
| DDX43 | DNAJC16 | 0.589065 | 3 | 0 | 3 |
| DDX43 | CDK16 | 0.586057 | 3 | 0 | 3 |
| DDX43 | BEX1 | 0.583669 | 3 | 0 | 3 |
| DDX43 | CHP2 | 0.576404 | 4 | 0 | 4 |
| DDX43 | HSD11B2 | 0.570418 | 4 | 0 | 3 |
| DDX43 | CCDC24 | 0.549118 | 3 | 0 | 3 |
| DDX43 | TAF5 | 0.547681 | 4 | 0 | 3 |
| DDX43 | RAD51C | 0.546485 | 4 | 0 | 3 |
| DDX43 | TIGD7 | 0.545748 | 3 | 0 | 3 |
For details and further investigation, click here
